Curated Information
Javascript is not enabled on this browser. This site will not work properly without Javascript.
PhosphoSitePlus Homepage PhosphoSitePlus® v6.6.0.2
Powered by Cell Signaling Technology
Home > Curated Information Page > PubMed Id: 29284690
Wang B, et al. (2017) AMPK╬▒2 Protects Against the Development of Heart Failure by Enhancing Mitophagy via PINK1 Phosphorylation. Circ Res 29284690
This page summarizes selected information from the record referenced above and curated into PhosphoSitePlus®, a comprehensive online resource for the study of protein post-translational modifications (NAR, 2015, 43:D512-20). To learn more about the scope of PhosphoSitePlus®, click here.
Click on the protein name to open the protein page, and on the RSD number to open the site page.
Download

S228-p - PINK1 (human)
Modsite: MWNISAGsSSEAILN SwissProt Entrez-Gene
Orthologous residues
PINK1 (human): S228‑p, PINK1 (mouse): S227‑p, PINK1 (rat): S227‑p
Upstream Regulation
Potential in vivo enzymes for site: 
Type Enzyme Evidence Notes
KINASE AMPKA2 (human) transfection of wild-type enzyme, phosphopeptide analysis
KINASE PINK1 (human) phosphopeptide analysis

S284-p - PINK1 (human)
Modsite: VLRAFTSsVPLLPGA SwissProt Entrez-Gene
Orthologous residues
PINK1 (human): S284‑p, PINK1 (mouse): S283‑p, PINK1 (rat): S283‑p
Upstream Regulation
Potential in vivo enzymes for site: 
Type Enzyme Evidence Notes
KINASE AMPKA2 (human) transfection of wild-type enzyme, phosphopeptide analysis

S495-p - PINK1 (human)
Modsite: ALLQREAsKRPSARV SwissProt Entrez-Gene
Orthologous residues
PINK1 (human): S495‑p, PINK1 (mouse): S494‑p, PINK1 (rat): N494‑p
Upstream Regulation
Potential in vivo enzymes for site: 
Type Enzyme Evidence Notes
KINASE AMPKA2 (human) transfection of wild-type enzyme, phosphopeptide analysis