Curated Information
Javascript is not enabled on this browser. This site will not work properly without Javascript.
PhosphoSitePlus Homepage PhosphoSitePlus® v6.6.0.2
Powered by Cell Signaling Technology
Home > Curated Information Page > PubMed Id: 25575814
Ho MY, Liang CM, Liang SM (2015) MIG-7 and phosphorylated prohibitin coordinately regulate lung cancer invasion/metastasis. Oncotarget 6, 381-93 25575814
This page summarizes selected information from the record referenced above and curated into PhosphoSitePlus®, a comprehensive online resource for the study of protein post-translational modifications (NAR, 2015, 43:D512-20). To learn more about the scope of PhosphoSitePlus®, click here.
Click on the protein name to open the protein page, and on the RSD number to open the site page.
Download

S473-p - Akt1 (human)
Modsite: RPHFPQFsysAsGtA SwissProt Entrez-Gene
Orthologous residues
Akt1 (human): S473‑p, Akt1 iso2 (human): S411‑p, Akt1 (mouse): S473‑p, Akt1 (rat): S473‑p, Akt1 (fruit fly): S586‑p, Akt1 (cow): S473‑p
Upstream Regulation
Treatments, proteins and their effect on site modification: 
Treatments Referenced Treatments Manipulated Protein Referenced Protein Effect Notes
EGF increase
HGF increase
IGF-1 increase
PGE2 increase
PIP3 increase
PIP3 Akt1 (human) increase Akt1-DN inhibits

S176-p - IKKA (human)
Modsite: AKDVDQGsLCtsFVG SwissProt Entrez-Gene
Orthologous residues
IKKA (human): S176‑p, IKKA (mouse): S176‑p, IKKA (rat): S176‑p
Upstream Regulation
Treatments, proteins and their effect on site modification: 
Treatments Referenced Treatments Manipulated Protein Referenced Protein Effect Notes
PIP3 increase
PIP3 Akt1 (human) increase Akt1-DN inhibits

S181-p - IKKB (human)
Modsite: DQGsLCtsFVGTLQy SwissProt Entrez-Gene
Orthologous residues
IKKB (human): S181‑p, IKKB (mouse): S181‑p, IKKB (rat): S181‑p
Upstream Regulation
Treatments, proteins and their effect on site modification: 
Treatments Referenced Treatments Manipulated Protein Referenced Protein Effect Notes
PIP3 increase
PIP3 Akt1 (human) increase Akt1-DN inhibits

S536-p - NFkB-p65 (human)
Modsite: sGDEDFSsIADMDFS SwissProt Entrez-Gene
Orthologous residues
NFkB‑p65 (human): S536‑p, NFkB‑p65 (mouse): S534‑p, NFkB‑p65 (rat): S535‑p

T258-p - PHB (human)
Modsite: LSRSRNItyLPAGQs SwissProt Entrez-Gene
Orthologous residues
PHB (human): T258‑p, PHB (mouse): T258‑p, PHB (rat): T258‑p, PHB (pig): T258‑p
Upstream Regulation
Treatments, proteins and their effect on site modification: 
Treatments Referenced Treatments Manipulated Protein Referenced Protein Effect Notes
EGF increase
HGF increase
IGF-1 increase
PGE2 increase

Y259-p - PHB (human)
Modsite: SRSRNItyLPAGQsV SwissProt Entrez-Gene
Orthologous residues
PHB (human): Y259‑p, PHB (mouse): Y259‑p, PHB (rat): Y259‑p, PHB (pig): Y259‑p

S338-p - RAF1 (human)
Modsite: RPRGQRDssyyWEIE SwissProt Entrez-Gene
Orthologous residues
RAF1 (human): S338‑p, RAF1 iso2 (human): S358‑p, RAF1 (mouse): S338‑p, RAF1 (rat): S338‑p, RAF1 (chicken): S338‑p