Curated Information
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Home > Curated Information Page > PubMed Id: 15091337
Sanada K, Gupta A, Tsai LH (2004) Disabled-1-regulated adhesion of migrating neurons to radial glial fiber contributes to neuronal positioning during early corticogenesis. Neuron 42, 197-211 15091337
This page summarizes selected information from the record referenced above and curated into PhosphoSitePlus®, a comprehensive online resource for the study of protein post-translational modifications (NAR, 2015, 43:D512-20). To learn more about the scope of PhosphoSitePlus®, click here.
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Y220-p - DAB1 (mouse)
Modsite: PETEENIyQVPTSQK SwissProt Entrez-Gene
Orthologous residues
DAB1 (human): Y220‑p, DAB1 (mouse): Y220‑p, DAB1 iso2 (mouse): Y220‑p, DAB1 iso3 (mouse): Y220‑p, DAB1 (rat): Y220‑p, DAB1 (pig): Y220‑p, DAB1 iso1 (pig): , DAB1 (chicken): Y220‑p, DAB1 iso2 (chicken):
Characterization
Methods used to characterize site in vivo mutation of modification site
Relevant cell lines - cell types - tissues:  'neuron, cortical'-brain
Cellular systems studied:  primary cells
Species studied:  mouse
Downstream Regulation
Effect of modification (function):  molecular association, regulation
Effect of modification (process):  cell adhesion, altered
Comments:  Y220 and Y232 phosphorylation may regulate DAB1 interaction with alpha3 integrin.

Y232-p - DAB1 (mouse)
Modsite: SQKKEGVyDVPKSQP SwissProt Entrez-Gene
Orthologous residues
DAB1 (human): Y232‑p, DAB1 (mouse): Y232‑p, DAB1 iso2 (mouse): Y232‑p, DAB1 iso3 (mouse): Y232‑p, DAB1 (rat): Y232‑p, DAB1 (pig): Y232‑p, DAB1 iso1 (pig): Y197‑p, DAB1 (chicken): Y232‑p, DAB1 iso2 (chicken): Y197‑p
Characterization
Methods used to characterize site in vivo mutation of modification site
Relevant cell lines - cell types - tissues:  'neuron, cortical'-brain
Cellular systems studied:  primary cells
Species studied:  mouse
Downstream Regulation
Effect of modification (function):  molecular association, regulation
Effect of modification (process):  cell adhesion, altered
Comments:  Y220 and Y232 phosphorylation may regulate DAB1 interaction with alpha3 integrin.