Curated Information
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Home > Curated Information Page > Cst Curation Set #3186
Li Y (2007) CST Curation Set: 3186; Year: 2007; Biosample/Treatment: tissue, colon/untreated; Disease: colorectal cancer; SILAC: -; Specificities of Antibodies Used to Purify Peptides prior to LCMS: pY Antibodies Used to Purify Peptides prior to LCMS: Phospho-Tyrosine Mouse mAb (P-Tyr-100) Cat#: 9411, PTMScan(R) Phospho-Tyr Motif (Y*) Immunoaffinity Beads Cat#: 1991
This page summarizes selected information from the record referenced above and curated into PhosphoSitePlus®, a comprehensive online resource for the study of protein post-translational modifications (NAR, 2015, 43:D512-20). To learn more about the scope of PhosphoSitePlus®, click here.
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Y55-p - ACTA1 (human)
Modsite: GMGQkDsyVGDEAQs SwissProt Entrez-Gene
Orthologous residues
ACTA1 (human): Y55‑p, ACTA1 (mouse): Y55‑p, ACTA1 (rat): Y55‑p, ACTA1 (rabbit): Y55‑p
Characterization
Methods used to characterize site in vivo mass spectrometry
Disease tissue studied:  colorectal cancer
Relevant cell lines - cell types - tissues:  colon
Cellular systems studied:  tissue
Species studied:  human

Y55-p - ACTA2 (human)
Modsite: GMGQkDsyVGDEAQs SwissProt Entrez-Gene
Orthologous residues
ACTA2 (human): Y55‑p, ACTA2 (mouse): Y55‑p, ACTA2 (rat): Y55‑p
Characterization
Methods used to characterize site in vivo mass spectrometry
Disease tissue studied:  colorectal cancer
Relevant cell lines - cell types - tissues:  colon
Cellular systems studied:  tissue
Species studied:  human

Y53-p - ACTB (human)
Modsite: GMGQkDsyVGDEAQs SwissProt Entrez-Gene
Orthologous residues
ACTB (human): Y53‑p, ACTB (mouse): Y53‑p, ACTB (rat): Y53‑p, ACTB (cow): Y53‑p
Characterization
Methods used to characterize site in vivo mass spectrometry
Disease tissue studied:  colorectal cancer
Relevant cell lines - cell types - tissues:  colon
Cellular systems studied:  tissue
Species studied:  human

Y55-p - ACTC1 (human)
Modsite: GMGQkDsyVGDEAQs SwissProt Entrez-Gene
Orthologous residues
ACTC1 (human): Y55‑p, ACTC1 (mouse): Y55‑p, ACTC1 (rat): Y55‑p
Characterization
Methods used to characterize site in vivo mass spectrometry
Disease tissue studied:  colorectal cancer
Relevant cell lines - cell types - tissues:  colon
Cellular systems studied:  tissue
Species studied:  human

Y53-p - ACTG1 (human)
Modsite: GMGQkDsyVGDEAQs SwissProt Entrez-Gene
Orthologous residues
ACTG1 (human): Y53‑p, ACTG1 (mouse): Y53‑p, ACTG1 (rat): Y53‑p
Characterization
Methods used to characterize site in vivo mass spectrometry
Disease tissue studied:  colorectal cancer
Relevant cell lines - cell types - tissues:  colon
Cellular systems studied:  tissue
Species studied:  human

Y54-p - ACTG2 (human)
Modsite: GMGQkDsyVGDEAQs SwissProt Entrez-Gene
Orthologous residues
ACTG2 (human): Y54‑p, ACTG2 (mouse): Y54‑p, ACTG2 (rat): Y54‑p
Characterization
Methods used to characterize site in vivo mass spectrometry
Disease tissue studied:  colorectal cancer
Relevant cell lines - cell types - tissues:  colon
Cellular systems studied:  tissue
Species studied:  human

T14-p - CDK1 (human)
Modsite: IEkIGEGtyGVVykG SwissProt Entrez-Gene
Orthologous residues
CDK1 (human): T14‑p, CDK1 iso2 (human): T14‑p, CDK1 (mouse): T14‑p, CDK1 (rat): T14‑p, CDK1 (chicken): T14‑p, CDK1 (fruit fly): T14‑p
Characterization
Methods used to characterize site in vivo mass spectrometry
Disease tissue studied:  colorectal cancer
Relevant cell lines - cell types - tissues:  colon
Cellular systems studied:  tissue
Species studied:  human

Y15-p - CDK1 (human)
Modsite: EkIGEGtyGVVykGR SwissProt Entrez-Gene
Orthologous residues
CDK1 (human): Y15‑p, CDK1 iso2 (human): Y15‑p, CDK1 (mouse): Y15‑p, CDK1 (rat): Y15‑p, CDK1 (chicken): Y15‑p, CDK1 (fruit fly): Y15‑p
Characterization
Methods used to characterize site in vivo mass spectrometry
Disease tissue studied:  colorectal cancer
Relevant cell lines - cell types - tissues:  colon
Cellular systems studied:  tissue
Species studied:  human

T14-p - CDK2 (human)
Modsite: VEkIGEGtyGVVykA SwissProt Entrez-Gene
Orthologous residues
CDK2 (human): T14‑p, CDK2 iso2 (human): T14‑p, CDK2 (mouse): T14‑p, CDK2 (rat): T14‑p
Characterization
Methods used to characterize site in vivo mass spectrometry
Disease tissue studied:  colorectal cancer
Relevant cell lines - cell types - tissues:  colon
Cellular systems studied:  tissue
Species studied:  human

Y15-p - CDK2 (human)
Modsite: EkIGEGtyGVVykAR SwissProt Entrez-Gene
Orthologous residues
CDK2 (human): Y15‑p, CDK2 iso2 (human): Y15‑p, CDK2 (mouse): Y15‑p, CDK2 (rat): Y15‑p
Characterization
Methods used to characterize site in vivo mass spectrometry
Disease tissue studied:  colorectal cancer
Relevant cell lines - cell types - tissues:  colon
Cellular systems studied:  tissue
Species studied:  human

T14-p - CDK3 (human)
Modsite: VEkIGEGtyGVVyKA SwissProt Entrez-Gene
Orthologous residues
CDK3 (human): T14‑p, CDK3 (mouse): T14‑p, CDK3 (cow): T14‑p
Characterization
Methods used to characterize site in vivo mass spectrometry
Disease tissue studied:  colorectal cancer
Relevant cell lines - cell types - tissues:  colon
Cellular systems studied:  tissue
Species studied:  human

Y15-p - CDK3 (human)
Modsite: EkIGEGtyGVVyKAK SwissProt Entrez-Gene
Orthologous residues
CDK3 (human): Y15‑p, CDK3 (mouse): Y15‑p, CDK3 (cow): Y15‑p
Characterization
Methods used to characterize site in vivo mass spectrometry
Disease tissue studied:  colorectal cancer
Relevant cell lines - cell types - tissues:  colon
Cellular systems studied:  tissue
Species studied:  human

Y198-p - Claudin-3 (human)
Modsite: ytAtkVVysAPRstG SwissProt Entrez-Gene
Orthologous residues
Claudin‑3 (human): Y198‑p, Claudin‑3 (mouse): Y197‑p, Claudin‑3 (rat): Y197‑p
Characterization
Methods used to characterize site in vivo mass spectrometry
Disease tissue studied:  colorectal cancer
Relevant cell lines - cell types - tissues:  colon
Cellular systems studied:  tissue
Species studied:  human

Y792-p - DDR1 (human)
Modsite: FGMsRNLyAGDyyRV SwissProt Entrez-Gene
Orthologous residues
DDR1 (human): Y792‑p, DDR1 iso2 (human): Y755‑p, DDR1 iso5 (human): Y798‑p, DDR1 (mouse): Y790‑p, DDR1 (rat): Y789‑p
Characterization
Methods used to characterize site in vivo mass spectrometry
Disease tissue studied:  colorectal cancer
Relevant cell lines - cell types - tissues:  colon
Cellular systems studied:  tissue
Species studied:  human

Y796-p - DDR1 (human)
Modsite: RNLyAGDyyRVQGRA SwissProt Entrez-Gene
Orthologous residues
DDR1 (human): Y796‑p, DDR1 iso2 (human): Y759‑p, DDR1 iso5 (human): Y802‑p, DDR1 (mouse): Y794‑p, DDR1 (rat): Y793‑p
Characterization
Methods used to characterize site in vivo mass spectrometry
Disease tissue studied:  colorectal cancer
Relevant cell lines - cell types - tissues:  colon
Cellular systems studied:  tissue
Species studied:  human

T202-p - ERK1 (human)
Modsite: HDHtGFLtEyVAtRW SwissProt Entrez-Gene
Orthologous residues
ERK1 (human): T202‑p, ERK1 iso2 (human): T202‑p, ERK1 iso3 (human): T202‑p, ERK1 (mouse): T203‑p, ERK1 (rat): T203‑p, ERK1 (hamster): T192‑p
Characterization
Methods used to characterize site in vivo mass spectrometry
Disease tissue studied:  colorectal cancer
Relevant cell lines - cell types - tissues:  colon
Cellular systems studied:  tissue
Species studied:  human

Y204-p - ERK1 (human)
Modsite: HtGFLtEyVAtRWyr SwissProt Entrez-Gene
Orthologous residues
ERK1 (human): Y204‑p, ERK1 iso2 (human): Y204‑p, ERK1 iso3 (human): Y204‑p, ERK1 (mouse): Y205‑p, ERK1 (rat): Y205‑p, ERK1 (hamster): Y194‑p
Characterization
Methods used to characterize site in vivo mass spectrometry
Disease tissue studied:  colorectal cancer
Relevant cell lines - cell types - tissues:  colon
Cellular systems studied:  tissue
Species studied:  human

Y822-p - ESYT1 (human)
Modsite: GTkHLsPyAtLtVGD SwissProt Entrez-Gene
Orthologous residues
ESYT1 (human): Y822‑p, ESYT1 iso2 (human): Y832‑p, ESYT1 (mouse): Y809‑p, ESYT1 (rat): Y811‑p
Characterization
Methods used to characterize site in vivo mass spectrometry
Disease tissue studied:  colorectal cancer
Relevant cell lines - cell types - tissues:  colon
Cellular systems studied:  tissue
Species studied:  human

S138-p - FETUA (human)
Modsite: kCDssPDsAEDVrkV SwissProt Entrez-Gene
Orthologous residues
FETUA (human): S138‑p, FETUA (mouse): S138‑p, FETUA (rat): S138‑p, FETUA (cow): S138‑p
Characterization
Methods used to characterize site in vivo mass spectrometry
Disease tissue studied:  colorectal cancer
Relevant cell lines - cell types - tissues:  colon
Cellular systems studied:  tissue
Species studied:  human

Y420-p - Fyn (human)
Modsite: RLIEDNEytARQGAk SwissProt Entrez-Gene
Orthologous residues
Fyn (human): Y420‑p, Fyn iso2 (human): Y417‑p, Fyn iso3 (human): Y365‑p, Fyn (mouse): Y420‑p, Fyn (rat): Y420‑p
Characterization
Methods used to characterize site in vivo mass spectrometry
Disease tissue studied:  colorectal cancer
Relevant cell lines - cell types - tissues:  colon
Cellular systems studied:  tissue
Species studied:  human

Y1105-p - GRF-1 (human)
Modsite: RNEEENIysVPHDst SwissProt Entrez-Gene
Orthologous residues
GRF‑1 (human): Y1105‑p, GRF‑1 (mouse): Y1105‑p, GRF‑1 (rat): Y1105‑p
Characterization
Methods used to characterize site in vivo mass spectrometry
Disease tissue studied:  colorectal cancer
Relevant cell lines - cell types - tissues:  colon
Cellular systems studied:  tissue
Species studied:  human

Y279-p - GSK3A (human)
Modsite: RGEPNVsyICsRyyR SwissProt Entrez-Gene
Orthologous residues
GSK3A (human): Y279‑p, GSK3A (mouse): Y279‑p, GSK3A (rat): Y279‑p, GSK3A (cow): Y279‑p
Characterization
Methods used to characterize site in vivo mass spectrometry
Disease tissue studied:  colorectal cancer
Relevant cell lines - cell types - tissues:  colon
Cellular systems studied:  tissue
Species studied:  human

S282-p - GSK3A (human)
Modsite: PNVsyICsRyyRAPE SwissProt Entrez-Gene
Orthologous residues
GSK3A (human): S282‑p, GSK3A (mouse): S282‑p, GSK3A (rat): S282‑p, GSK3A (cow): S282‑p
Characterization
Methods used to characterize site in vivo mass spectrometry
Disease tissue studied:  colorectal cancer
Relevant cell lines - cell types - tissues:  colon
Cellular systems studied:  tissue
Species studied:  human

Y216-p - GSK3B (human)
Modsite: RGEPNVsyICsRyyR SwissProt Entrez-Gene
Orthologous residues
GSK3B (human): Y216‑p, GSK3B iso2 (human): Y216‑p, GSK3B (mouse): Y216‑p, GSK3B (rat): Y216‑p, GSK3B (rabbit): Y216‑p
Characterization
Methods used to characterize site in vivo mass spectrometry
Disease tissue studied:  colorectal cancer
Relevant cell lines - cell types - tissues:  colon
Cellular systems studied:  tissue
Species studied:  human

S219-p - GSK3B (human)
Modsite: PNVsyICsRyyRAPE SwissProt Entrez-Gene
Orthologous residues
GSK3B (human): S219‑p, GSK3B iso2 (human): S219‑p, GSK3B (mouse): S219‑p, GSK3B (rat): S219‑p, GSK3B (rabbit): S219‑p
Characterization
Methods used to characterize site in vivo mass spectrometry
Disease tissue studied:  colorectal cancer
Relevant cell lines - cell types - tissues:  colon
Cellular systems studied:  tissue
Species studied:  human

Y411-p - Hck (human)
Modsite: RVIEDNEytAREGAk SwissProt Entrez-Gene
Orthologous residues
Hck (human): Y411‑p, Hck iso2 (human): Y390‑p, Hck iso3 (human): Y389‑p, Hck iso4 (human): Y410‑p, Hck (mouse): Y409‑p, Hck (rat): Y409‑p
Characterization
Methods used to characterize site in vivo mass spectrometry
Disease tissue studied:  colorectal cancer
Relevant cell lines - cell types - tissues:  colon
Cellular systems studied:  tissue
Species studied:  human

Y359-p - HIPK3 (human)
Modsite: SkTVCstyLQsRYYR SwissProt Entrez-Gene
Orthologous residues
HIPK3 (human): Y359‑p, HIPK3 iso2 (human): Y359‑p, HIPK3 (mouse): Y359‑p, HIPK3 (rat): Y359‑p
Characterization
Methods used to characterize site in vivo mass spectrometry
Disease tissue studied:  colorectal cancer
Relevant cell lines - cell types - tissues:  colon
Cellular systems studied:  tissue
Species studied:  human

Y394-p - Lck (human)
Modsite: RLIEDNEytAREGAk SwissProt Entrez-Gene
Orthologous residues
Lck (human): Y394‑p, Lck iso3 (human): Y424‑p, Lck (mouse): Y394‑p, Lck (rat): Y394‑p
Characterization
Methods used to characterize site in vivo mass spectrometry
Disease tissue studied:  colorectal cancer
Relevant cell lines - cell types - tissues:  colon
Cellular systems studied:  tissue
Species studied:  human

Y397-p - LYN (human)
Modsite: RVIEDNEytAREGAk SwissProt Entrez-Gene
Orthologous residues
LYN (human): Y397‑p, LYN iso2 (human): Y376‑p, LYN (mouse): Y397‑p, LYN iso2 (mouse): Y376‑p, LYN (rat): Y397‑p
Characterization
Methods used to characterize site in vivo mass spectrometry
Disease tissue studied:  colorectal cancer
Relevant cell lines - cell types - tissues:  colon
Cellular systems studied:  tissue
Species studied:  human

S1954-p - MYH11 (human)
Modsite: VIENADGsEEEtDtR SwissProt Entrez-Gene
Orthologous residues
MYH11 (human): S1954‑p, MYH11 iso2 (human): S1961‑p, MYH11 iso3 (human): , MYH11 iso4 (human): , MYH11 (mouse): S1954‑p, MYH11 (rat): S1954‑p
Characterization
Methods used to characterize site in vivo mass spectrometry
Disease tissue studied:  colorectal cancer
Relevant cell lines - cell types - tissues:  colon
Cellular systems studied:  tissue
Species studied:  human

T180-p - P38A (human)
Modsite: RHtDDEMtGyVAtRW SwissProt Entrez-Gene
Orthologous residues
P38A (human): T180‑p, P38A iso2 (human): T180‑p, P38A (mouse): T180‑p, P38A iso3 (mouse): T180‑p, P38A (rat): T180‑p, P38A (salmonid): T181‑p
Characterization
Methods used to characterize site in vivo mass spectrometry
Disease tissue studied:  colorectal cancer
Relevant cell lines - cell types - tissues:  colon
Cellular systems studied:  tissue
Species studied:  human

Y182-p - P38A (human)
Modsite: tDDEMtGyVAtRWYR SwissProt Entrez-Gene
Orthologous residues
P38A (human): Y182‑p, P38A iso2 (human): Y182‑p, P38A (mouse): Y182‑p, P38A iso3 (mouse): Y182‑p, P38A (rat): Y182‑p, P38A (salmonid): Y183‑p
Characterization
Methods used to characterize site in vivo mass spectrometry
Disease tissue studied:  colorectal cancer
Relevant cell lines - cell types - tissues:  colon
Cellular systems studied:  tissue
Species studied:  human

Y334-p - PPP2R3A (human)
Modsite: GTEQPPKyEDVVQLs SwissProt Entrez-Gene
Orthologous residues
PPP2R3A (human): Y334‑p, PPP2R3A iso2 (human): , PPP2R3A (mouse): Y333‑p, PPP2R3A (rat): Y333‑p
Characterization
Methods used to characterize site in vivo mass spectrometry
Disease tissue studied:  colorectal cancer
Relevant cell lines - cell types - tissues:  colon
Cellular systems studied:  tissue
Species studied:  human

S341-p - PPP2R3A (human)
Modsite: yEDVVQLsAsDsGRF SwissProt Entrez-Gene
Orthologous residues
PPP2R3A (human): S341‑p, PPP2R3A iso2 (human): , PPP2R3A (mouse): S340‑p, PPP2R3A (rat): S340‑p
Characterization
Methods used to characterize site in vivo mass spectrometry
Disease tissue studied:  colorectal cancer
Relevant cell lines - cell types - tissues:  colon
Cellular systems studied:  tissue
Species studied:  human

S343-p - PPP2R3A (human)
Modsite: DVVQLsAsDsGRFQT SwissProt Entrez-Gene
Orthologous residues
PPP2R3A (human): S343‑p, PPP2R3A iso2 (human): , PPP2R3A (mouse): L342‑p, PPP2R3A (rat): L342‑p
Characterization
Methods used to characterize site in vivo mass spectrometry
Disease tissue studied:  colorectal cancer
Relevant cell lines - cell types - tissues:  colon
Cellular systems studied:  tissue
Species studied:  human

S345-p - PPP2R3A (human)
Modsite: VQLsAsDsGRFQTIE SwissProt Entrez-Gene
Orthologous residues
PPP2R3A (human): S345‑p, PPP2R3A iso2 (human): , PPP2R3A (mouse): S344‑p, PPP2R3A (rat): S344‑p
Characterization
Methods used to characterize site in vivo mass spectrometry
Disease tissue studied:  colorectal cancer
Relevant cell lines - cell types - tissues:  colon
Cellular systems studied:  tissue
Species studied:  human

Y849-p - PRP4 (human)
Modsite: ADNDItPyLVsRFyR SwissProt Entrez-Gene
Orthologous residues
PRP4 (human): Y849‑p, PRP4 (mouse): Y849‑p, PRP4 (rat): Y849‑p
Characterization
Methods used to characterize site in vivo mass spectrometry
Disease tissue studied:  colorectal cancer
Relevant cell lines - cell types - tissues:  colon
Cellular systems studied:  tissue
Species studied:  human

S250-p - PSMA3 (human)
Modsite: sLkEEDEsDDDNM__ SwissProt Entrez-Gene
Orthologous residues
PSMA3 (human): S250‑p, PSMA3 iso2 (human): S243‑p, PSMA3 (mouse): S250‑p, PSMA3 (rat): S250‑p
Characterization
Methods used to characterize site in vivo mass spectrometry
Disease tissue studied:  colorectal cancer
Relevant cell lines - cell types - tissues:  colon
Cellular systems studied:  tissue
Species studied:  human

S189-p - SPAG6 (human)
Modsite: ALKRIAAsALSDIAK SwissProt Entrez-Gene
Orthologous residues
SPAG6 (human): S189‑p, SPAG6 (mouse): S189‑p, SPAG6 (rat): S189‑p
Characterization
Methods used to characterize site in vivo mass spectrometry
Disease tissue studied:  colorectal cancer
Relevant cell lines - cell types - tissues:  colon
Cellular systems studied:  tissue
Species studied:  human

Y419-p - Src (human)
Modsite: RLIEDNEytARQGAk SwissProt Entrez-Gene
Orthologous residues
Src (human): Y419‑p, Src iso2 (human): Y425‑p, Src (mouse): Y418‑p, Src iso1 (mouse): Y424‑p, Src (rat): Y419‑p, Src (chicken): Y416‑p
Characterization
Methods used to characterize site in vivo mass spectrometry
Disease tissue studied:  colorectal cancer
Relevant cell lines - cell types - tissues:  colon
Cellular systems studied:  tissue
Species studied:  human

Y705-p - STAT3 (human)
Modsite: DPGsAAPyLktkFIC SwissProt Entrez-Gene
Orthologous residues
STAT3 (human): Y705‑p, STAT3 iso2 (human): Y704‑p, STAT3 iso3 (human): Y705‑p, STAT3 (mouse): Y705‑p, STAT3 iso2 (mouse): Y705‑p, STAT3 iso3 (mouse): Y704‑p, STAT3 (rat): Y705‑p, STAT3 (cow): Y705‑p
Characterization
Methods used to characterize site in vivo mass spectrometry
Disease tissue studied:  colorectal cancer
Relevant cell lines - cell types - tissues:  colon
Cellular systems studied:  tissue
Species studied:  human

Y822-p - Vinculin (human)
Modsite: ksFLDsGyRILGAVA SwissProt Entrez-Gene
Orthologous residues
Vinculin (human): Y822‑p, Vinculin iso2 (human): Y822‑p, Vinculin (mouse): Y822‑p, Vinculin (rat): Y822‑p, Vinculin (chicken): Y822‑p, Vinculin (dog): Y822‑p, Vinculin (cow): Y822‑p
Characterization
Methods used to characterize site in vivo mass spectrometry
Disease tissue studied:  colorectal cancer
Relevant cell lines - cell types - tissues:  colon
Cellular systems studied:  tissue
Species studied:  human

Y426-p - Yes (human)
Modsite: RLIEDNEytARQGAk SwissProt Entrez-Gene
Orthologous residues
Yes (human): Y426‑p, Yes (mouse): Y424‑p, Yes (rat): Y424‑p
Characterization
Methods used to characterize site in vivo mass spectrometry
Disease tissue studied:  colorectal cancer
Relevant cell lines - cell types - tissues:  colon
Cellular systems studied:  tissue
Species studied:  human