Joughin BA, et al. (2009) An integrated comparative phosphoproteomic and bioinformatic approach reveals a novel class of MPM-2 motifs upregulated in EGFRvIII-expressing glioblastoma cells. Mol Biosyst 5, 59-67 19081932

This page summarizes selected information from the record referenced above and curated into PhosphoSitePlus®, a comprehensive online resource for the study of protein post-translational modifications (NAR, 2015, 43:D512-20). To learn more about the scope of PhosphoSitePlus®, click here.

Click on the protein name to open the protein page, and on the RSD number to open the site page.

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T37-p - 4E-BP1 (human) ▲

Modsite: PPGDysttPGGtLFs SwissProt Entrez-Gene Orthologous residues 4E‑BP1 (human): T37‑p, 4E‑BP1 (mouse): T36‑p, 4E‑BP1 (rat): T36‑p, 4E‑BP1 (fruit fly): T37‑p, 4E‑BP1 (cow): T37‑p Characterization Methods used to characterize site in vivo:  mass spectrometry Disease tissue studied:  brain cancer, glioblastoma, glioma Relevant cell lines - cell types - tissues:  U87MG (glial) Cellular systems studied:  cell lines Species studied:  human

T45-p - 4E-BP1 (human) ▲

Modsite: PGGtLFsttPGGtRI SwissProt Entrez-Gene Orthologous residues 4E‑BP1 (human): T45‑p, 4E‑BP1 (mouse): T44‑p, 4E‑BP1 (rat): T44‑p, 4E‑BP1 (fruit fly): T45‑p, 4E‑BP1 (cow): T45‑p Characterization Methods used to characterize site in vivo:  mass spectrometry Disease tissue studied:  brain cancer, glioblastoma, glioma Relevant cell lines - cell types - tissues:  U87MG (glial) Cellular systems studied:  cell lines Species studied:  human

T46-p - 4E-BP1 (human) ▲

Modsite: GGtLFsttPGGtRII SwissProt Entrez-Gene Orthologous residues 4E‑BP1 (human): T46‑p, 4E‑BP1 (mouse): T45‑p, 4E‑BP1 (rat): T45‑p, 4E‑BP1 (fruit fly): T46‑p, 4E‑BP1 (cow): T46‑p Characterization Methods used to characterize site in vivo:  mass spectrometry Disease tissue studied:  brain cancer, glioblastoma, glioma Relevant cell lines - cell types - tissues:  U87MG (glial) Cellular systems studied:  cell lines Species studied:  human

T37-p - 4E-BP2 (human) ▲
Modsite: LPHDyCttPGGtLFs SwissProt Entrez-Gene Orthologous residues 4E‑BP2 (human): T37‑p, 4E‑BP2 (mouse): T37‑p, 4E‑BP2 (rat): T37‑p Characterization Methods used to characterize site in vivo:  mass spectrometry Disease tissue studied:  brain cancer, glioblastoma, glioma Relevant cell lines - cell types - tissues:  U87MG (glial) Cellular systems studied:  cell lines Species studied:  human

T46-p - 4E-BP2 (human) ▲
Modsite: GGtLFsttPGGtRII SwissProt Entrez-Gene Orthologous residues 4E‑BP2 (human): T46‑p, 4E‑BP2 (mouse): T46‑p, 4E‑BP2 (rat): T46‑p Characterization Methods used to characterize site in vivo:  mass spectrometry Disease tissue studied:  brain cancer, glioblastoma, glioma Relevant cell lines - cell types - tissues:  U87MG (glial) Cellular systems studied:  cell lines Species studied:  human

S456-p - AKAP11 (human) ▲
Modsite: PIRSSAFsPLGGCTP SwissProt Entrez-Gene Orthologous residues AKAP11 (human): S456‑p, AKAP11 (mouse): S456‑p, AKAP11 (rat): S456‑p Characterization Methods used to characterize site in vivo:  mass spectrometry Disease tissue studied:  brain cancer, glioblastoma, glioma Relevant cell lines - cell types - tissues:  U87MG (glial) Cellular systems studied:  cell lines Species studied:  human

T135-p - ARF GAP1 (human) ▲

Modsite: ssPAQNWtPPQPRtL SwissProt Entrez-Gene Orthologous residues ARF GAP1 (human): T135‑p, ARF GAP1 iso2 (human): T135‑p, ARF GAP1 (mouse): T135‑p, ARF GAP1 (rat): T135‑p Characterization Methods used to characterize site in vivo:  mass spectrometry Disease tissue studied:  brain cancer, glioblastoma, glioma Relevant cell lines - cell types - tissues:  U87MG (glial) Cellular systems studied:  cell lines Species studied:  human

S112-p - ATF-2 (human) ▲
Modsite: kKMPLDLsPLAtPII SwissProt Entrez-Gene Orthologous residues ATF‑2 (human): S112‑p, ATF‑2 (mouse): S94‑p, ATF‑2 (rat): S94‑p Characterization Methods used to characterize site in vivo:  mass spectrometry Disease tissue studied:  brain cancer, glioblastoma, glioma Relevant cell lines - cell types - tissues:  U87MG (glial) Cellular systems studied:  cell lines Species studied:  human

S385-p - BCLAF1 (human) ▲

Modsite: QEALDyFsDKEsGKQ SwissProt Entrez-Gene Orthologous residues BCLAF1 (human): S385‑p, BCLAF1 iso2 (human): S383‑p, BCLAF1 iso3 (human): S383‑p, BCLAF1 iso4 (human): ‑, BCLAF1 (mouse): S383‑p, BCLAF1 (rat): S385‑p, BCLAF1 iso3 (rat): S526‑p, BCLAF1 (cow): S385‑p Characterization Methods used to characterize site in vivo:  mass spectrometry Disease tissue studied:  brain cancer, glioblastoma, glioma Relevant cell lines - cell types - tissues:  U87MG (glial) Cellular systems studied:  cell lines Species studied:  human

S1420-p - CHD-8 (human) ▲

Modsite: DDDLVEFsDLEsEDD SwissProt Entrez-Gene Orthologous residues CHD‑8 (human): S1420‑p, CHD‑8 iso2 (human): S1141‑p, CHD‑8 (mouse): S1422‑p, CHD‑8 iso2 (mouse): ‑, CHD‑8 (rat): S1420‑p Characterization Methods used to characterize site in vivo:  mass spectrometry Disease tissue studied:  brain cancer, glioblastoma, glioma Relevant cell lines - cell types - tissues:  U87MG (glial) Cellular systems studied:  cell lines Species studied:  human Upstream Regulation Treatments, proteins and their effect on site modification:  Treatments Referenced Treatments Manipulated Protein Referenced Protein Effect Notes EGFR (human) increase increased in cells expressing high levels of EGFR vs. kinase-dead EGFR

S1424-p - CHD-8 (human) ▲

Modsite: VEFsDLEsEDDERPR SwissProt Entrez-Gene Orthologous residues CHD‑8 (human): S1424‑p, CHD‑8 iso2 (human): S1145‑p, CHD‑8 (mouse): S1426‑p, CHD‑8 iso2 (mouse): ‑, CHD‑8 (rat): S1424‑p Characterization Methods used to characterize site in vivo:  mass spectrometry Disease tissue studied:  brain cancer, glioblastoma, glioma Relevant cell lines - cell types - tissues:  U87MG (glial) Cellular systems studied:  cell lines Species studied:  human Upstream Regulation Treatments, proteins and their effect on site modification:  Treatments Referenced Treatments Manipulated Protein Referenced Protein Effect Notes EGFR (human) increase increased in cells expressing high levels of EGFR vs. kinase-dead EGFR

S456-p - EHD1 (human) ▲
Modsite: DEIFytLsPVNGKIT SwissProt Entrez-Gene Orthologous residues EHD1 (human): S456‑p, EHD1 (mouse): S456‑p, EHD1 (rat): S456‑p Characterization Methods used to characterize site in vivo:  mass spectrometry Disease tissue studied:  brain cancer, glioblastoma, glioma Relevant cell lines - cell types - tissues:  U87MG (glial) Cellular systems studied:  cell lines Species studied:  human

S459-p - EHD4 (human) ▲
Modsite: DELFytLsPINGKIS SwissProt Entrez-Gene Orthologous residues EHD4 (human): S459‑p, EHD4 (mouse): S459‑p, EHD4 (rat): S459‑p Characterization Methods used to characterize site in vivo:  mass spectrometry Disease tissue studied:  brain cancer, glioblastoma, glioma Relevant cell lines - cell types - tissues:  U87MG (glial) Cellular systems studied:  cell lines Species studied:  human

S39-p - EIF3C (human) ▲
Modsite: GKQPLLLsEDEEDtK SwissProt Entrez-Gene Orthologous residues EIF3C (human): S39‑p, EIF3C (mouse): S39‑p, EIF3C (rat): S39‑p Characterization Methods used to characterize site in vivo:  mass spectrometry Disease tissue studied:  brain cancer, glioblastoma, glioma Relevant cell lines - cell types - tissues:  U87MG (glial) Cellular systems studied:  cell lines Species studied:  human

S39-p - EIF3CL (human) ▲
Modsite: GKQPLLLsEDEEDtK SwissProt Entrez-Gene Orthologous residues EIF3CL (human): S39‑p Characterization Methods used to characterize site in vivo:  mass spectrometry Disease tissue studied:  brain cancer, glioblastoma, glioma Relevant cell lines - cell types - tissues:  U87MG (glial) Cellular systems studied:  cell lines Species studied:  human

S429-p - ERCC6 (human) ▲
Modsite: IDDDFFPssGEEAEA SwissProt Entrez-Gene Orthologous residues ERCC6 (human): S429‑p, ERCC6 (mouse): S428‑p, ERCC6 (rat): S405‑p Characterization Methods used to characterize site in vivo:  mass spectrometry Disease tissue studied:  brain cancer, glioblastoma, glioma Relevant cell lines - cell types - tissues:  U87MG (glial) Cellular systems studied:  cell lines Species studied:  human

S430-p - ERCC6 (human) ▲
Modsite: DDDFFPssGEEAEAA SwissProt Entrez-Gene Orthologous residues ERCC6 (human): S430‑p, ERCC6 (mouse): S429‑p, ERCC6 (rat): S406‑p Characterization Methods used to characterize site in vivo:  mass spectrometry Disease tissue studied:  brain cancer, glioblastoma, glioma Relevant cell lines - cell types - tissues:  U87MG (glial) Cellular systems studied:  cell lines Species studied:  human

S788-p - FAM40B (human) ▲
Modsite: RPQDSEFsPVDNCLQ SwissProt Entrez-Gene Orthologous residues FAM40B (human): S788‑p, FAM40B (mouse): S798‑p, FAM40B (rat): S793‑p Characterization Methods used to characterize site in vivo:  mass spectrometry Disease tissue studied:  brain cancer, glioblastoma, glioma Relevant cell lines - cell types - tissues:  U87MG (glial) Cellular systems studied:  cell lines Species studied:  human

T2204-p - FASN (human) ▲

Modsite: AsELACPtPkEDGLA SwissProt Entrez-Gene Orthologous residues FASN (human): T2204‑p, FASN (mouse): K2198‑p, FASN (rat): K2199‑p, FASN (cow): T2206‑p Characterization Methods used to characterize site in vivo:  mass spectrometry Disease tissue studied:  brain cancer, glioblastoma, glioma Relevant cell lines - cell types - tissues:  U87MG (glial) Cellular systems studied:  cell lines Species studied:  human

S138-p - FZR1 (human) ▲

Modsite: sLsTkRssPDDGNDV SwissProt Entrez-Gene Orthologous residues FZR1 (human): S138‑p, FZR1 iso2 (human): S138‑p, FZR1 (mouse): S138‑p, FZR1 (rat): S138‑p Characterization Methods used to characterize site in vivo:  mass spectrometry Disease tissue studied:  brain cancer, glioblastoma, glioma Relevant cell lines - cell types - tissues:  U87MG (glial) Cellular systems studied:  cell lines Species studied:  human Upstream Regulation Treatments, proteins and their effect on site modification:  Treatments Referenced Treatments Manipulated Protein Referenced Protein Effect Notes EGFR (human) increase increased in cells expressing high levels of EGFR vs. kinase-dead EGFR

S151-p - FZR1 (human) ▲

Modsite: DVsPYSLsPVsNkSQ SwissProt Entrez-Gene Orthologous residues FZR1 (human): S151‑p, FZR1 iso2 (human): S151‑p, FZR1 (mouse): S151‑p, FZR1 (rat): S151‑p Characterization Methods used to characterize site in vivo:  mass spectrometry Disease tissue studied:  brain cancer, glioblastoma, glioma Relevant cell lines - cell types - tissues:  U87MG (glial) Cellular systems studied:  cell lines Species studied:  human Upstream Regulation Treatments, proteins and their effect on site modification:  Treatments Referenced Treatments Manipulated Protein Referenced Protein Effect Notes EGFR (human) increase increased in cells expressing high levels of EGFR vs. kinase-dead EGFR

S1328-p - HERC1 (human) ▲

Modsite: SSRDRWIsENQDsAD SwissProt Entrez-Gene Orthologous residues HERC1 (human): S1328‑p, HERC1 (mouse): T1328‑p, HERC1 (rat): S1328‑p Characterization Methods used to characterize site in vivo:  mass spectrometry Disease tissue studied:  brain cancer, glioblastoma, glioma Relevant cell lines - cell types - tissues:  U87MG (glial) Cellular systems studied:  cell lines Species studied:  human Upstream Regulation Treatments, proteins and their effect on site modification:  Treatments Referenced Treatments Manipulated Protein Referenced Protein Effect Notes EGFR (human) increase increased in cells expressing high levels of EGFR vs. kinase-dead EGFR

S310-p - hnRNP F (human) ▲
Modsite: NDIyNFFsPLNPVRV SwissProt Entrez-Gene Orthologous residues hnRNP F (human): S310‑p, hnRNP F (mouse): S310‑p, hnRNP F (rat): S310‑p Characterization Methods used to characterize site in vivo:  mass spectrometry Disease tissue studied:  brain cancer, glioblastoma, glioma Relevant cell lines - cell types - tissues:  U87MG (glial) Cellular systems studied:  cell lines Species studied:  human

S310-p - hnRNP H1 (human) ▲

Modsite: NDIyNFFsPLNPVRV SwissProt Entrez-Gene Orthologous residues hnRNP H1 (human): S310‑p, hnRNP H1 (mouse): S310‑p, hnRNP H1 (rat): S310‑p Characterization Methods used to characterize site in vivo:  mass spectrometry Disease tissue studied:  brain cancer, glioblastoma, glioma Relevant cell lines - cell types - tissues:  U87MG (glial) Cellular systems studied:  cell lines Species studied:  human

T1923-p - KI-67 (human) ▲

Modsite: DINtFVGtPVEkLDL SwissProt Entrez-Gene Orthologous residues KI‑67 (human): T1923‑p, KI‑67 iso2 (human): T1563‑p, KI‑67 (mouse): T1884‑p, KI‑67 (rat): T1903‑p, KI‑67 iso4 (rat): T1903‑p Characterization Methods used to characterize site in vivo:  mass spectrometry Disease tissue studied:  brain cancer, glioblastoma, glioma Relevant cell lines - cell types - tissues:  U87MG (glial) Cellular systems studied:  cell lines Species studied:  human

T993-p - KNL2 (human) ▲
Modsite: HDDFFSttPLQHQRI SwissProt Entrez-Gene Orthologous residues KNL2 (human): T993‑p, KNL2 (mouse): T857‑p, KNL2 (rat): T849‑p Characterization Methods used to characterize site in vivo:  mass spectrometry Disease tissue studied:  brain cancer, glioblastoma, glioma Relevant cell lines - cell types - tissues:  U87MG (glial) Cellular systems studied:  cell lines Species studied:  human

T732-p - LRIF1 (human) ▲
Modsite: TEDIFPVtPPELEET SwissProt Entrez-Gene Orthologous residues LRIF1 (human): T732‑p, LRIF1 (mouse): T717‑p, LRIF1 (rat): T710‑p Characterization Methods used to characterize site in vivo:  mass spectrometry Disease tissue studied:  brain cancer, glioblastoma, glioma Relevant cell lines - cell types - tissues:  U87MG (glial) Cellular systems studied:  cell lines Species studied:  human

S526-p - MAP1A (human) ▲

Modsite: GHRELVLssPEDLtQ SwissProt Entrez-Gene Orthologous residues MAP1A (human): S526‑p, MAP1A iso2 (human): S526‑p, MAP1A (mouse): S526‑p, MAP1A (rat): S526‑p Characterization Methods used to characterize site in vivo:  mass spectrometry Disease tissue studied:  brain cancer, glioblastoma, glioma Relevant cell lines - cell types - tissues:  U87MG (glial) Cellular systems studied:  cell lines Species studied:  human

S527-p - MAP1A (human) ▲

Modsite: HRELVLssPEDLtQD SwissProt Entrez-Gene Orthologous residues MAP1A (human): S527‑p, MAP1A iso2 (human): S527‑p, MAP1A (mouse): S527‑p, MAP1A (rat): S527‑p Characterization Methods used to characterize site in vivo:  mass spectrometry Disease tissue studied:  brain cancer, glioblastoma, glioma Relevant cell lines - cell types - tissues:  U87MG (glial) Cellular systems studied:  cell lines Species studied:  human

T1067-p - MAP1B (human) ▲

Modsite: EQyGFLttPtKQLGA SwissProt Entrez-Gene Orthologous residues MAP1B (human): T1067‑p, MAP1B (mouse): T1064‑p, MAP1B (rat): T1061‑p, MAP1B (cow): M1059‑p Characterization Methods used to characterize site in vivo:  mass spectrometry Disease tissue studied:  brain cancer, glioblastoma, glioma Relevant cell lines - cell types - tissues:  U87MG (glial) Cellular systems studied:  cell lines Species studied:  human

T1282-p - MAP1B (human) ▲

Modsite: RsVNFsLtPNEIKVS SwissProt Entrez-Gene Orthologous residues MAP1B (human): T1282‑p, MAP1B (mouse): T1277‑p, MAP1B (rat): T1274‑p, MAP1B (cow): T1276‑p Characterization Methods used to characterize site in vivo:  mass spectrometry Disease tissue studied:  brain cancer, glioblastoma, glioma Relevant cell lines - cell types - tissues:  U87MG (glial) Cellular systems studied:  cell lines Species studied:  human

T1788-p - MAP1B (human) ▲

Modsite: KsDIsPLtPREssPL SwissProt Entrez-Gene Orthologous residues MAP1B (human): T1788‑p, MAP1B (mouse): T1784‑p, MAP1B (rat): T1781‑p, MAP1B (cow): T1783‑p Characterization Methods used to characterize site in vivo:  mass spectrometry Disease tissue studied:  brain cancer, glioblastoma, glioma Relevant cell lines - cell types - tissues:  U87MG (glial) Cellular systems studied:  cell lines Species studied:  human

S1793-p - MAP1B (human) ▲

Modsite: PLtPREssPLysPtF SwissProt Entrez-Gene Orthologous residues MAP1B (human): S1793‑p, MAP1B (mouse): S1789‑p, MAP1B (rat): S1786‑p, MAP1B (cow): S1788‑p Characterization Methods used to characterize site in vivo:  mass spectrometry Disease tissue studied:  brain cancer, glioblastoma, glioma Relevant cell lines - cell types - tissues:  U87MG (glial) Cellular systems studied:  cell lines Species studied:  human

S694-p - MCEF (human) ▲

Modsite: FFRQRMFsPMEEKEL SwissProt Entrez-Gene Orthologous residues MCEF (human): S694‑p, MCEF iso2 (human): S694‑p, MCEF (mouse): S689‑p, MCEF (rat): S681‑p Characterization Methods used to characterize site in vivo:  mass spectrometry Disease tissue studied:  brain cancer, glioblastoma, glioma Relevant cell lines - cell types - tissues:  U87MG (glial) Cellular systems studied:  cell lines Species studied:  human Upstream Regulation Treatments, proteins and their effect on site modification:  Treatments Referenced Treatments Manipulated Protein Referenced Protein Effect Notes EGFR (human) increase increased in cells expressing high levels of EGFR vs. kinase-dead EGFR

T722-p - MCM3 (human) ▲

Modsite: EEMPQVHtPKtADsQ SwissProt Entrez-Gene Orthologous residues MCM3 (human): T722‑p, MCM3 iso2 (human): T767‑p, MCM3 (mouse): T719‑p, MCM3 (rat): T721‑p Characterization Methods used to characterize site in vivo:  mass spectrometry Disease tissue studied:  brain cancer, glioblastoma, glioma Relevant cell lines - cell types - tissues:  U87MG (glial) Cellular systems studied:  cell lines Species studied:  human Upstream Regulation Treatments, proteins and their effect on site modification:  Treatments Referenced Treatments Manipulated Protein Referenced Protein Effect Notes EGFR (human) increase increased in cells expressing high levels of EGFR vs. kinase-dead EGFR

S98-p - MEF2A (human) ▲

Modsite: KEHRGCDsPDPDtsy SwissProt Entrez-Gene Orthologous residues MEF2A (human): S98‑p, MEF2A iso2 (human): ‑, MEF2A (mouse): ‑, MEF2A iso3 (mouse): S98‑p, MEF2A (rat): S98‑p Characterization Methods used to characterize site in vivo:  mass spectrometry Disease tissue studied:  brain cancer, glioblastoma, glioma Relevant cell lines - cell types - tissues:  U87MG (glial) Cellular systems studied:  cell lines Species studied:  human Upstream Regulation Treatments, proteins and their effect on site modification:  Treatments Referenced Treatments Manipulated Protein Referenced Protein Effect Notes EGFR (human) increase increased in cells expressing high levels of EGFR vs. kinase-dead EGFR

T108-p - MEF2A (human) ▲

Modsite: PDtsyVLtPHtEEKy SwissProt Entrez-Gene Orthologous residues MEF2A (human): T108‑p, MEF2A iso2 (human): ‑, MEF2A (mouse): ‑, MEF2A iso3 (mouse): T108‑p, MEF2A (rat): T108‑p Characterization Methods used to characterize site in vivo:  mass spectrometry Disease tissue studied:  brain cancer, glioblastoma, glioma Relevant cell lines - cell types - tissues:  U87MG (glial) Cellular systems studied:  cell lines Species studied:  human Upstream Regulation Treatments, proteins and their effect on site modification:  Treatments Referenced Treatments Manipulated Protein Referenced Protein Effect Notes EGFR (human) increase increased in cells expressing high levels of EGFR vs. kinase-dead EGFR

S517-p - MIA2 iso7 (human) ▲

Modsite: tAFGREHsPyGPsPL SwissProt Entrez-Gene Orthologous residues MIA2 (human): S1125‑p, MIA2 iso2 (human): ‑, MIA2 iso7 (human): S517‑p, MIA2 iso8 (human): ‑, MIA2 iso9 (human): S488‑p, MIA2 iso10 (human): S517‑p, MIA2 (mouse): S1112‑p, MIA2 iso3 (mouse): S493‑p, MIA2 (rat): S1121‑p, MIA2 iso2 (rat): S479‑p Characterization Methods used to characterize site in vivo:  mass spectrometry Disease tissue studied:  brain cancer, glioblastoma, glioma Relevant cell lines - cell types - tissues:  U87MG (glial) Cellular systems studied:  cell lines Species studied:  human Upstream Regulation Treatments, proteins and their effect on site modification:  Treatments Referenced Treatments Manipulated Protein Referenced Protein Effect Notes EGFR (human) increase increased in cells expressing high levels of EGFR vs. kinase-dead EGFR

S522-p - MIA2 iso7 (human) ▲

Modsite: EHsPyGPsPLGWPSS SwissProt Entrez-Gene Orthologous residues MIA2 (human): S1130‑p, MIA2 iso2 (human): ‑, MIA2 iso7 (human): S522‑p, MIA2 iso8 (human): ‑, MIA2 iso9 (human): S493‑p, MIA2 iso10 (human): S522‑p, MIA2 (mouse): S1117‑p, MIA2 iso3 (mouse): S498‑p, MIA2 (rat): S1126‑p, MIA2 iso2 (rat): S484‑p Characterization Methods used to characterize site in vivo:  mass spectrometry Disease tissue studied:  brain cancer, glioblastoma, glioma Relevant cell lines - cell types - tissues:  U87MG (glial) Cellular systems studied:  cell lines Species studied:  human Upstream Regulation Treatments, proteins and their effect on site modification:  Treatments Referenced Treatments Manipulated Protein Referenced Protein Effect Notes EGFR (human) increase increased in cells expressing high levels of EGFR vs. kinase-dead EGFR

S163-p - MPHOSPH10 (human) ▲

Modsite: SKsDLRKsPVFsDED SwissProt Entrez-Gene Orthologous residues MPHOSPH10 (human): S163‑p, MPHOSPH10 (mouse): S164‑p, MPHOSPH10 (rat): S164‑p Characterization Methods used to characterize site in vivo:  mass spectrometry Disease tissue studied:  brain cancer, glioblastoma, glioma Relevant cell lines - cell types - tissues:  U87MG (glial) Cellular systems studied:  cell lines Species studied:  human Upstream Regulation Treatments, proteins and their effect on site modification:  Treatments Referenced Treatments Manipulated Protein Referenced Protein Effect Notes EGFR (human) increase increased in cells expressing high levels of EGFR vs. kinase-dead EGFR

S167-p - MPHOSPH10 (human) ▲

Modsite: LRKsPVFsDEDsDLD SwissProt Entrez-Gene Orthologous residues MPHOSPH10 (human): S167‑p, MPHOSPH10 (mouse): S168‑p, MPHOSPH10 (rat): S168‑p Characterization Methods used to characterize site in vivo:  mass spectrometry Disease tissue studied:  brain cancer, glioblastoma, glioma Relevant cell lines - cell types - tissues:  U87MG (glial) Cellular systems studied:  cell lines Species studied:  human Upstream Regulation Treatments, proteins and their effect on site modification:  Treatments Referenced Treatments Manipulated Protein Referenced Protein Effect Notes EGFR (human) increase increased in cells expressing high levels of EGFR vs. kinase-dead EGFR

S171-p - MPHOSPH10 (human) ▲

Modsite: PVFsDEDsDLDFDIS SwissProt Entrez-Gene Orthologous residues MPHOSPH10 (human): S171‑p, MPHOSPH10 (mouse): S172‑p, MPHOSPH10 (rat): S172‑p Characterization Methods used to characterize site in vivo:  mass spectrometry Disease tissue studied:  brain cancer, glioblastoma, glioma Relevant cell lines - cell types - tissues:  U87MG (glial) Cellular systems studied:  cell lines Species studied:  human Upstream Regulation Treatments, proteins and their effect on site modification:  Treatments Referenced Treatments Manipulated Protein Referenced Protein Effect Notes EGFR (human) increase increased in cells expressing high levels of EGFR vs. kinase-dead EGFR

T147-p - MPHOSPH6 (human) ▲

Modsite: EDENGDItPIkAKkM SwissProt Entrez-Gene Orthologous residues MPHOSPH6 (human): T147‑p, MPHOSPH6 (mouse): K148‑p, MPHOSPH6 (rat): K147‑p Characterization Methods used to characterize site in vivo:  mass spectrometry Disease tissue studied:  brain cancer, glioblastoma, glioma Relevant cell lines - cell types - tissues:  U87MG (glial) Cellular systems studied:  cell lines Species studied:  human Upstream Regulation Treatments, proteins and their effect on site modification:  Treatments Referenced Treatments Manipulated Protein Referenced Protein Effect Notes EGFR (human) increase increased in cells expressing high levels of EGFR vs. kinase-dead EGFR

S149-p - NKAP (human) ▲
Modsite: APEVWGLsPkNPEPD SwissProt Entrez-Gene Orthologous residues NKAP (human): S149‑p, NKAP (mouse): S147‑p, NKAP (rat): S147‑p Characterization Methods used to characterize site in vivo:  mass spectrometry Disease tissue studied:  brain cancer, glioblastoma, glioma Relevant cell lines - cell types - tissues:  U87MG (glial) Cellular systems studied:  cell lines Species studied:  human

S1769-p - NuMA-1 (human) ▲

Modsite: RLPPkVEsLEsLyFt SwissProt Entrez-Gene Orthologous residues NuMA‑1 (human): S1769‑p, NuMA‑1 iso2 (human): S1755‑p, NuMA‑1 iso4 (human): ‑, NuMA‑1 (mouse): S1751‑p, NuMA‑1 (rat): S1735‑p Characterization Methods used to characterize site in vivo:  mass spectrometry Disease tissue studied:  brain cancer, glioblastoma, glioma Relevant cell lines - cell types - tissues:  U87MG (glial) Cellular systems studied:  cell lines Species studied:  human

T1776-p - NuMA-1 (human) ▲

Modsite: sLEsLyFtPIPARsQ SwissProt Entrez-Gene Orthologous residues NuMA‑1 (human): T1776‑p, NuMA‑1 iso2 (human): T1762‑p, NuMA‑1 iso4 (human): ‑, NuMA‑1 (mouse): T1758‑p, NuMA‑1 (rat): T1742‑p Characterization Methods used to characterize site in vivo:  mass spectrometry Disease tissue studied:  brain cancer, glioblastoma, glioma Relevant cell lines - cell types - tissues:  U87MG (glial) Cellular systems studied:  cell lines Species studied:  human

S612-p - NUP98 (human) ▲

Modsite: LNNsNLFsPVNRDsE SwissProt Entrez-Gene Orthologous residues NUP98 (human): S612‑p, NUP98 iso2 (human): S595‑p, NUP98 iso5 (human): S595‑p, NUP98 iso6 (human): S612‑p, NUP98 (mouse): S612‑p, NUP98 (rat): S612‑p Characterization Methods used to characterize site in vivo:  mass spectrometry Disease tissue studied:  brain cancer, glioblastoma, glioma Relevant cell lines - cell types - tissues:  U87MG (glial) Cellular systems studied:  cell lines Species studied:  human

S623-p - NUP98 (human) ▲

Modsite: RDsENLAsPsEyPEN SwissProt Entrez-Gene Orthologous residues NUP98 (human): S623‑p, NUP98 iso2 (human): S606‑p, NUP98 iso5 (human): S606‑p, NUP98 iso6 (human): S623‑p, NUP98 (mouse): S623‑p, NUP98 (rat): S623‑p Characterization Methods used to characterize site in vivo:  mass spectrometry Disease tissue studied:  brain cancer, glioblastoma, glioma Relevant cell lines - cell types - tissues:  U87MG (glial) Cellular systems studied:  cell lines Species studied:  human

T137-p - PDE5A (human) ▲

Modsite: KKEQMPLtPPRFDHD SwissProt Entrez-Gene Orthologous residues PDE5A (human): T137‑p, PDE5A (mouse): T127‑p, PDE5A (rat): T95‑p, PDE5A (cow): T127‑p Characterization Methods used to characterize site in vivo:  mass spectrometry Disease tissue studied:  brain cancer, glioblastoma, glioma Relevant cell lines - cell types - tissues:  U87MG (glial) Cellular systems studied:  cell lines Species studied:  human

S181-p - PGRMC1 (human) ▲

Modsite: GEEPtVysDEEEPkD SwissProt Entrez-Gene Orthologous residues PGRMC1 (human): S181‑p, PGRMC1 (mouse): S181‑p, PGRMC1 (rat): S181‑p, PGRMC1 (pig): S180‑p Characterization Methods used to characterize site in vivo:  mass spectrometry Disease tissue studied:  brain cancer, glioblastoma, glioma Relevant cell lines - cell types - tissues:  U87MG (glial) Cellular systems studied:  cell lines Species studied:  human

T211-p - PGRMC2 (human) ▲

Modsite: GEEPsEytDEEDtKD SwissProt Entrez-Gene Orthologous residues PGRMC2 (human): T211‑p, PGRMC2 iso2 (human): T235‑p, PGRMC2 (mouse): T205‑p, PGRMC2 (rat): T205‑p Characterization Methods used to characterize site in vivo:  mass spectrometry Disease tissue studied:  brain cancer, glioblastoma, glioma Relevant cell lines - cell types - tissues:  U87MG (glial) Cellular systems studied:  cell lines Species studied:  human

S450-p - PRPF31 (human) ▲

Modsite: DRssGtAssVAFtPL SwissProt Entrez-Gene Orthologous residues PRPF31 (human): S450‑p, PRPF31 iso2 (human): ‑, PRPF31 iso3 (human): ‑, PRPF31 (mouse): S450‑p, PRPF31 (rat): S450‑p Characterization Methods used to characterize site in vivo:  mass spectrometry Disease tissue studied:  brain cancer, glioblastoma, glioma Relevant cell lines - cell types - tissues:  U87MG (glial) Cellular systems studied:  cell lines Species studied:  human

T455-p - PRPF31 (human) ▲

Modsite: tAssVAFtPLQGLEI SwissProt Entrez-Gene Orthologous residues PRPF31 (human): T455‑p, PRPF31 iso2 (human): ‑, PRPF31 iso3 (human): ‑, PRPF31 (mouse): T455‑p, PRPF31 (rat): T455‑p Characterization Methods used to characterize site in vivo:  mass spectrometry Disease tissue studied:  brain cancer, glioblastoma, glioma Relevant cell lines - cell types - tissues:  U87MG (glial) Cellular systems studied:  cell lines Species studied:  human

T2639-p - RANBP2 (human) ▲

Modsite: VLIVYELtPtAEQKA SwissProt Entrez-Gene Orthologous residues RANBP2 (human): T2639‑p, RANBP2 (mouse): T2476‑p, RANBP2 (rat): T2511‑p, RANBP2 (cow): T2455‑p Characterization Methods used to characterize site in vivo:  mass spectrometry Disease tissue studied:  brain cancer, glioblastoma, glioma Relevant cell lines - cell types - tissues:  U87MG (glial) Cellular systems studied:  cell lines Species studied:  human

S608-p - Rb (human) ▲

Modsite: tAADMyLsPVRsPKK SwissProt Entrez-Gene Orthologous residues Rb (human): S608‑p, Rb (mouse): S601‑p, Rb (rat): S600‑p Characterization Methods used to characterize site in vivo:  mass spectrometry Disease tissue studied:  brain cancer, glioblastoma, glioma Relevant cell lines - cell types - tissues:  U87MG (glial) Cellular systems studied:  cell lines Species studied:  human Upstream Regulation Treatments, proteins and their effect on site modification:  Treatments Referenced Treatments Manipulated Protein Referenced Protein Effect Notes EGFR (human) increase increased in cells expressing high levels of EGFR vs. kinase-dead EGFR

S612-p - Rb (human) ▲

Modsite: MyLsPVRsPKKKGsT SwissProt Entrez-Gene Orthologous residues Rb (human): S612‑p, Rb (mouse): S605‑p, Rb (rat): S604‑p Characterization Methods used to characterize site in vivo:  mass spectrometry Disease tissue studied:  brain cancer, glioblastoma, glioma Relevant cell lines - cell types - tissues:  U87MG (glial) Cellular systems studied:  cell lines Species studied:  human Upstream Regulation Treatments, proteins and their effect on site modification:  Treatments Referenced Treatments Manipulated Protein Referenced Protein Effect Notes EGFR (human) increase increased in cells expressing high levels of EGFR vs. kinase-dead EGFR

T385-p - Rb-like 1 (human) ▲

Modsite: REKEAVItPVAsATQ SwissProt Entrez-Gene Orthologous residues Rb‑like 1 (human): T385‑p, Rb‑like 1 iso2 (human): T385‑p, Rb‑like 1 (mouse): T385‑p, Rb‑like 1 (rat): T385‑p Characterization Methods used to characterize site in vivo:  mass spectrometry Disease tissue studied:  brain cancer, glioblastoma, glioma Relevant cell lines - cell types - tissues:  U87MG (glial) Cellular systems studied:  cell lines Species studied:  human Upstream Regulation Treatments, proteins and their effect on site modification:  Treatments Referenced Treatments Manipulated Protein Referenced Protein Effect Notes EGFR (human) increase increased in cells expressing high levels of EGFR vs. kinase-dead EGFR

S163-p - RCAN1 (human) ▲

Modsite: PDKQFLIsPPAsPPV SwissProt Entrez-Gene Orthologous residues RCAN1 (human): S163‑p, RCAN1 iso2 (human): S108‑p, RCAN1 iso3 (human): S82‑p, RCAN1 (mouse): S161‑p, RCAN1 (rat): S108‑p Characterization Methods used to characterize site in vivo:  mass spectrometry Disease tissue studied:  brain cancer, glioblastoma, glioma Relevant cell lines - cell types - tissues:  U87MG (glial) Cellular systems studied:  cell lines Species studied:  human

S167-p - RCAN1 (human) ▲

Modsite: FLIsPPAsPPVGWKQ SwissProt Entrez-Gene Orthologous residues RCAN1 (human): S167‑p, RCAN1 iso2 (human): S112‑p, RCAN1 iso3 (human): S86‑p, RCAN1 (mouse): S165‑p, RCAN1 (rat): S112‑p Characterization Methods used to characterize site in vivo:  mass spectrometry Disease tissue studied:  brain cancer, glioblastoma, glioma Relevant cell lines - cell types - tissues:  U87MG (glial) Cellular systems studied:  cell lines Species studied:  human

S148-p - RCAN3 (human) ▲
Modsite: PVKQFLIsPPAsPPV SwissProt Entrez-Gene Orthologous residues RCAN3 (human): S148‑p, RCAN3 (mouse): S148‑p, RCAN3 (rat): S165‑p Characterization Methods used to characterize site in vivo:  mass spectrometry Disease tissue studied:  brain cancer, glioblastoma, glioma Relevant cell lines - cell types - tissues:  U87MG (glial) Cellular systems studied:  cell lines Species studied:  human

S152-p - RCAN3 (human) ▲
Modsite: FLIsPPAsPPVGWKQ SwissProt Entrez-Gene Orthologous residues RCAN3 (human): S152‑p, RCAN3 (mouse): S152‑p, RCAN3 (rat): S169‑p Characterization Methods used to characterize site in vivo:  mass spectrometry Disease tissue studied:  brain cancer, glioblastoma, glioma Relevant cell lines - cell types - tissues:  U87MG (glial) Cellular systems studied:  cell lines Species studied:  human

S374-p - RPRD2 (human) ▲

Modsite: DVEDMELsDVEDDGS SwissProt Entrez-Gene Orthologous residues RPRD2 (human): S374‑p, RPRD2 iso2 (human): S337‑p, RPRD2 iso3 (human): S348‑p, RPRD2 iso5 (human): S348‑p, RPRD2 (mouse): S392‑p, RPRD2 iso2 (mouse): S348‑p, RPRD2 (rat): S263‑p, RPRD2 (cow): S374‑p Characterization Methods used to characterize site in vivo:  mass spectrometry Disease tissue studied:  brain cancer, glioblastoma, glioma Relevant cell lines - cell types - tissues:  U87MG (glial) Cellular systems studied:  cell lines Species studied:  human

T221-p - RPS3 (human) ▲
Modsite: kDEILPttPIsEQkG SwissProt Entrez-Gene Orthologous residues RPS3 (human): T221‑p, RPS3 (mouse): T221‑p, RPS3 (rat): T221‑p Characterization Methods used to characterize site in vivo:  mass spectrometry Disease tissue studied:  brain cancer, glioblastoma, glioma Relevant cell lines - cell types - tissues:  U87MG (glial) Cellular systems studied:  cell lines Species studied:  human

S20-p - RRM2 (human) ▲

Modsite: DPQQLQLsPLkGLsL SwissProt Entrez-Gene Orthologous residues RRM2 (human): S20‑p, RRM2 iso2 (human): S80‑p, RRM2 (mouse): S20‑p, RRM2 (rat): S20‑p, RRM2 (cow): S17‑p Characterization Methods used to characterize site in vivo:  mass spectrometry Disease tissue studied:  brain cancer, glioblastoma, glioma Relevant cell lines - cell types - tissues:  U87MG (glial) Cellular systems studied:  cell lines Species studied:  human

S203-p - SCD (human) ▲

Modsite: kGstLDLsDLEAEkL SwissProt Entrez-Gene Orthologous residues SCD (human): S203‑p, SCD (mouse): S199‑p, SCD (rat): S202‑p Characterization Methods used to characterize site in vivo:  mass spectrometry Disease tissue studied:  brain cancer, glioblastoma, glioma Relevant cell lines - cell types - tissues:  U87MG (glial) Cellular systems studied:  cell lines Species studied:  human Upstream Regulation Treatments, proteins and their effect on site modification:  Treatments Referenced Treatments Manipulated Protein Referenced Protein Effect Notes EGFR (human) increase increased in cells expressing high levels of EGFR vs. kinase-dead EGFR

S417-p - SDCCAG1 (human) ▲

Modsite: LRNPyLLsEEEDDDV SwissProt Entrez-Gene Orthologous residues SDCCAG1 (human): S417‑p, SDCCAG1 iso3 (human): S417‑p, SDCCAG1 (mouse): S417‑p, SDCCAG1 (rat): S417‑p Characterization Methods used to characterize site in vivo:  mass spectrometry Disease tissue studied:  brain cancer, glioblastoma, glioma Relevant cell lines - cell types - tissues:  U87MG (glial) Cellular systems studied:  cell lines Species studied:  human

S101-p - SKA2 (human) ▲

Modsite: kQTDLELsPLtkEEK SwissProt Entrez-Gene Orthologous residues SKA2 (human): S101‑p, SKA2 iso2 (human): ‑, SKA2 (mouse): T101‑p, SKA2 (rat): T101‑p Characterization Methods used to characterize site in vivo:  mass spectrometry Disease tissue studied:  brain cancer, glioblastoma, glioma Relevant cell lines - cell types - tissues:  U87MG (glial) Cellular systems studied:  cell lines Species studied:  human Upstream Regulation Treatments, proteins and their effect on site modification:  Treatments Referenced Treatments Manipulated Protein Referenced Protein Effect Notes EGFR (human) increase increased in cells expressing high levels of EGFR vs. kinase-dead EGFR

S315-p - SLAIN2 (human) ▲

Modsite: stRRGtFsDQELDAQ SwissProt Entrez-Gene Orthologous residues SLAIN2 (human): S315‑p, SLAIN2 (mouse): S316‑p, SLAIN2 iso2 (mouse): S316‑p, SLAIN2 (rat): S316‑p Characterization Methods used to characterize site in vivo:  mass spectrometry Disease tissue studied:  brain cancer, glioblastoma, glioma Relevant cell lines - cell types - tissues:  U87MG (glial) Cellular systems studied:  cell lines Species studied:  human

S343-p - SLAIN2 (human) ▲

Modsite: yPAVNRFsPsPRNsP SwissProt Entrez-Gene Orthologous residues SLAIN2 (human): S343‑p, SLAIN2 (mouse): S344‑p, SLAIN2 iso2 (mouse): S344‑p, SLAIN2 (rat): S344‑p Characterization Methods used to characterize site in vivo:  mass spectrometry Disease tissue studied:  brain cancer, glioblastoma, glioma Relevant cell lines - cell types - tissues:  U87MG (glial) Cellular systems studied:  cell lines Species studied:  human

S345-p - SLAIN2 (human) ▲

Modsite: AVNRFsPsPRNsPRP SwissProt Entrez-Gene Orthologous residues SLAIN2 (human): S345‑p, SLAIN2 (mouse): S346‑p, SLAIN2 iso2 (mouse): S346‑p, SLAIN2 (rat): S346‑p Characterization Methods used to characterize site in vivo:  mass spectrometry Disease tissue studied:  brain cancer, glioblastoma, glioma Relevant cell lines - cell types - tissues:  U87MG (glial) Cellular systems studied:  cell lines Species studied:  human

S146-p - SMARCAD1 (human) ▲

Modsite: ARRNDDIsELEDLsE SwissProt Entrez-Gene Orthologous residues SMARCAD1 (human): S146‑p, SMARCAD1 iso2 (human): S146‑p, SMARCAD1 (mouse): S145‑p, SMARCAD1 (rat): S145‑p Characterization Methods used to characterize site in vivo:  mass spectrometry Disease tissue studied:  brain cancer, glioblastoma, glioma Relevant cell lines - cell types - tissues:  U87MG (glial) Cellular systems studied:  cell lines Species studied:  human Upstream Regulation Treatments, proteins and their effect on site modification:  Treatments Referenced Treatments Manipulated Protein Referenced Protein Effect Notes EGFR (human) increase increased in cells expressing high levels of EGFR vs. kinase-dead EGFR

S152-p - SMARCAD1 (human) ▲

Modsite: IsELEDLsELEDLkD SwissProt Entrez-Gene Orthologous residues SMARCAD1 (human): S152‑p, SMARCAD1 iso2 (human): S152‑p, SMARCAD1 (mouse): S151‑p, SMARCAD1 (rat): S151‑p Characterization Methods used to characterize site in vivo:  mass spectrometry Disease tissue studied:  brain cancer, glioblastoma, glioma Relevant cell lines - cell types - tissues:  U87MG (glial) Cellular systems studied:  cell lines Species studied:  human

T708-p - SMPD4 (human) ▲

Modsite: GEDGLILtPLGRYQI SwissProt Entrez-Gene Orthologous residues SMPD4 (human): T708‑p, SMPD4 iso2 (human): T679‑p, SMPD4 iso4 (human): T754‑p, SMPD4 (mouse): T665‑p, SMPD4 iso3 (mouse): T635‑p, SMPD4 (rat): T665‑p Characterization Methods used to characterize site in vivo:  mass spectrometry Disease tissue studied:  brain cancer, glioblastoma, glioma Relevant cell lines - cell types - tissues:  U87MG (glial) Cellular systems studied:  cell lines Species studied:  human

S2011-p - SON (human) ▲

Modsite: VVRRRsFsIsPVRLR SwissProt Entrez-Gene Orthologous residues SON (human): S2011‑p, SON iso3 (human): S2011‑p, SON iso5 (human): S2011‑p, SON iso6 (human): S2011‑p, SON iso9 (human): S2051‑p, SON iso10 (human): S2011‑p, SON (mouse): S2029‑p, SON iso2 (mouse): S2029‑p, SON (rat): S2031‑p, SON iso2 (rat): S2031‑p Characterization Methods used to characterize site in vivo:  mass spectrometry Disease tissue studied:  brain cancer, glioblastoma, glioma Relevant cell lines - cell types - tissues:  U87MG (glial) Cellular systems studied:  cell lines Species studied:  human

S2013-p - SON (human) ▲

Modsite: RRRsFsIsPVRLRRs SwissProt Entrez-Gene Orthologous residues SON (human): S2013‑p, SON iso3 (human): S2013‑p, SON iso5 (human): S2013‑p, SON iso6 (human): S2013‑p, SON iso9 (human): S2053‑p, SON iso10 (human): S2013‑p, SON (mouse): S2031‑p, SON iso2 (mouse): S2031‑p, SON (rat): S2033‑p, SON iso2 (rat): S2033‑p Characterization Methods used to characterize site in vivo:  mass spectrometry Disease tissue studied:  brain cancer, glioblastoma, glioma Relevant cell lines - cell types - tissues:  U87MG (glial) Cellular systems studied:  cell lines Species studied:  human

T269-p - SQSTM1 (human) ▲

Modsite: GGkRsRLtPVsPEss SwissProt Entrez-Gene Orthologous residues SQSTM1 (human): T269‑p, SQSTM1 iso2 (human): T185‑p, SQSTM1 (mouse): T269‑p, SQSTM1 iso2 (mouse): T269‑p, SQSTM1 (rat): T266‑p, SQSTM1 iso2 (rat): T239‑p, SQSTM1 iso3 (rat): ‑ Characterization Methods used to characterize site in vivo:  mass spectrometry Disease tissue studied:  brain cancer, glioblastoma, glioma Relevant cell lines - cell types - tissues:  U87MG (glial) Cellular systems studied:  cell lines Species studied:  human

S272-p - SQSTM1 (human) ▲

Modsite: RsRLtPVsPEssstE SwissProt Entrez-Gene Orthologous residues SQSTM1 (human): S272‑p, SQSTM1 iso2 (human): S188‑p, SQSTM1 (mouse): T272‑p, SQSTM1 iso2 (mouse): T272‑p, SQSTM1 (rat): S269‑p, SQSTM1 iso2 (rat): S242‑p, SQSTM1 iso3 (rat): ‑ Characterization Methods used to characterize site in vivo:  mass spectrometry Disease tissue studied:  brain cancer, glioblastoma, glioma Relevant cell lines - cell types - tissues:  U87MG (glial) Cellular systems studied:  cell lines Species studied:  human

S1124-p - SRm300 (human) ▲

Modsite: DRGEFsAsPMLKsGM SwissProt Entrez-Gene Orthologous residues SRm300 (human): S1124‑p, SRm300 iso2 (human): S1124‑p, SRm300 (mouse): D1089‑p, SRm300 iso2 (mouse): D993‑p, SRm300 iso3 (mouse): D1089‑p, SRm300 (rat): D1091‑p, SRm300 (cow): S1093‑p Characterization Methods used to characterize site in vivo:  mass spectrometry Disease tissue studied:  brain cancer, glioblastoma, glioma Relevant cell lines - cell types - tissues:  U87MG (glial) Cellular systems studied:  cell lines Species studied:  human

S1320-p - SRm300 (human) ▲

Modsite: EHKELsNsPLRENsF SwissProt Entrez-Gene Orthologous residues SRm300 (human): S1320‑p, SRm300 iso2 (human): S1320‑p, SRm300 (mouse): S1278‑p, SRm300 iso2 (mouse): S1182‑p, SRm300 iso3 (mouse): S1278‑p, SRm300 (rat): S1280‑p, SRm300 (cow): S1287‑p Characterization Methods used to characterize site in vivo:  mass spectrometry Disease tissue studied:  brain cancer, glioblastoma, glioma Relevant cell lines - cell types - tissues:  U87MG (glial) Cellular systems studied:  cell lines Species studied:  human

S1329-p - SRm300 (human) ▲

Modsite: LRENsFGsPLEFRNs SwissProt Entrez-Gene Orthologous residues SRm300 (human): S1329‑p, SRm300 iso2 (human): S1329‑p, SRm300 (mouse): S1287‑p, SRm300 iso2 (mouse): S1191‑p, SRm300 iso3 (mouse): S1287‑p, SRm300 (rat): ‑, SRm300 (cow): S1296‑p Characterization Methods used to characterize site in vivo:  mass spectrometry Disease tissue studied:  brain cancer, glioblastoma, glioma Relevant cell lines - cell types - tissues:  U87MG (glial) Cellular systems studied:  cell lines Species studied:  human

S366-p - SSB (human) ▲
Modsite: GkktKFAsDDEHDEH SwissProt Entrez-Gene Orthologous residues SSB (human): S366‑p, SSB (mouse): D381‑p, SSB (rat): D381‑p Characterization Methods used to characterize site in vivo:  mass spectrometry Disease tissue studied:  brain cancer, glioblastoma, glioma Relevant cell lines - cell types - tissues:  U87MG (glial) Cellular systems studied:  cell lines Species studied:  human

T190-p - SURF2 (human) ▲

Modsite: stEDGDGtDDFLtDK SwissProt Entrez-Gene Orthologous residues SURF2 (human): T190‑p, SURF2 (mouse): P191‑p, SURF2 (rat): P190‑p Characterization Methods used to characterize site in vivo:  mass spectrometry Disease tissue studied:  brain cancer, glioblastoma, glioma Relevant cell lines - cell types - tissues:  U87MG (glial) Cellular systems studied:  cell lines Species studied:  human Upstream Regulation Treatments, proteins and their effect on site modification:  Treatments Referenced Treatments Manipulated Protein Referenced Protein Effect Notes EGFR (human) increase increased in cells expressing high levels of EGFR vs. kinase-dead EGFR

T195-p - SURF2 (human) ▲

Modsite: DGtDDFLtDKEDEKA SwissProt Entrez-Gene Orthologous residues SURF2 (human): T195‑p, SURF2 (mouse): T196‑p, SURF2 (rat): T195‑p Characterization Methods used to characterize site in vivo:  mass spectrometry Disease tissue studied:  brain cancer, glioblastoma, glioma Relevant cell lines - cell types - tissues:  U87MG (glial) Cellular systems studied:  cell lines Species studied:  human Upstream Regulation Treatments, proteins and their effect on site modification:  Treatments Referenced Treatments Manipulated Protein Referenced Protein Effect Notes EGFR (human) increase increased in cells expressing high levels of EGFR vs. kinase-dead EGFR

S133-p - TMEM51 (human) ▲
Modsite: ASRyYVPsyEEVMNt SwissProt Entrez-Gene Orthologous residues TMEM51 (human): S133‑p, TMEM51 (mouse): S129‑p, TMEM51 (rat): S129‑p Characterization Methods used to characterize site in vivo:  mass spectrometry Disease tissue studied:  brain cancer, glioblastoma, glioma Relevant cell lines - cell types - tissues:  U87MG (glial) Cellular systems studied:  cell lines Species studied:  human

S1413-p - TOP2B (human) ▲

Modsite: GEDEFVPsDGLDKDE SwissProt Entrez-Gene Orthologous residues TOP2B (human): S1413‑p, TOP2B iso2 (human): S1408‑p, TOP2B (mouse): S1400‑p, TOP2B (rat): S1400‑p Characterization Methods used to characterize site in vivo:  mass spectrometry Disease tissue studied:  brain cancer, glioblastoma, glioma Relevant cell lines - cell types - tissues:  U87MG (glial) Cellular systems studied:  cell lines Species studied:  human

T874-p - Trap150 (human) ▲

Modsite: EEWDPEytPksKkyy SwissProt Entrez-Gene Orthologous residues Trap150 (human): T874‑p, Trap150 (mouse): T870‑p, Trap150 (rat): T870‑p, Trap150 (cow): T877‑p Characterization Methods used to characterize site in vivo:  mass spectrometry Disease tissue studied:  brain cancer, glioblastoma, glioma Relevant cell lines - cell types - tissues:  U87MG (glial) Cellular systems studied:  cell lines Species studied:  human

S352-p - WASHC2A (human) ▲

Modsite: KLtDEDFsPFGsGGG SwissProt Entrez-Gene Orthologous residues WASHC2A (human): S352‑p, WASHC2A iso2 (human): S352‑p, WASHC2A iso3 (human): S352‑p, WASHC2A (mouse): S343‑p, WASHC2A (rat): S342‑p Characterization Methods used to characterize site in vivo:  mass spectrometry Disease tissue studied:  brain cancer, glioblastoma, glioma Relevant cell lines - cell types - tissues:  U87MG (glial) Cellular systems studied:  cell lines Species studied:  human Upstream Regulation Treatments, proteins and their effect on site modification:  Treatments Referenced Treatments Manipulated Protein Referenced Protein Effect Notes EGFR (human) increase increased in cells expressing high levels of EGFR vs. kinase-dead EGFR

S352-p - WASHC2C (human) ▲

Modsite: KLtDEDFsPFGsGGG SwissProt Entrez-Gene Orthologous residues WASHC2C (human): S352‑p, WASHC2C iso2 (human): S344‑p Characterization Methods used to characterize site in vivo:  mass spectrometry Disease tissue studied:  brain cancer, glioblastoma, glioma Relevant cell lines - cell types - tissues:  U87MG (glial) Cellular systems studied:  cell lines Species studied:  human Upstream Regulation Treatments, proteins and their effect on site modification:  Treatments Referenced Treatments Manipulated Protein Referenced Protein Effect Notes EGFR (human) increase increased in cells expressing high levels of EGFR vs. kinase-dead EGFR

S1263-p - YTHDC2 (human) ▲
Modsite: TDSSSYPsPCAsPsP SwissProt Entrez-Gene Orthologous residues YTHDC2 (human): S1263‑p, YTHDC2 (mouse): S1278‑p, YTHDC2 (rat): S1264‑p Characterization Methods used to characterize site in vivo:  mass spectrometry Disease tissue studied:  brain cancer, glioblastoma, glioma Relevant cell lines - cell types - tissues:  U87MG (glial) Cellular systems studied:  cell lines Species studied:  human

S1267-p - YTHDC2 (human) ▲
Modsite: SYPsPCAsPsPPssG SwissProt Entrez-Gene Orthologous residues YTHDC2 (human): S1267‑p, YTHDC2 (mouse): S1282‑p, YTHDC2 (rat): S1268‑p Characterization Methods used to characterize site in vivo:  mass spectrometry Disease tissue studied:  brain cancer, glioblastoma, glioma Relevant cell lines - cell types - tissues:  U87MG (glial) Cellular systems studied:  cell lines Species studied:  human

S993-p - ZC3H13 (human) ▲

Modsite: sEDGQVFsPKKGQKK SwissProt Entrez-Gene Orthologous residues ZC3H13 (human): S993‑p, ZC3H13 iso2 (human): S993‑p, ZC3H13 (mouse): S1069‑p, ZC3H13 iso4 (mouse): S1069‑p, ZC3H13 (rat): S1067‑p, ZC3H13 (cow): S993‑p Characterization Methods used to characterize site in vivo:  mass spectrometry Disease tissue studied:  brain cancer, glioblastoma, glioma Relevant cell lines - cell types - tissues:  U87MG (glial) Cellular systems studied:  cell lines Species studied:  human