Curated Information
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Home > Curated Information Page > PubMed Id: 24396068
Sgarbanti M, et al. (2014) IκB Kinase {varepsilon} Targets Interferon Regulatory Factor 1 in Activated T Lymphocytes. Mol Cell Biol 34, 1054-65 24396068
This page summarizes selected information from the record referenced above and curated into PhosphoSitePlus®, a comprehensive online resource for the study of protein post-translational modifications (NAR, 2015, 43:D512-20). To learn more about the scope of PhosphoSitePlus®, click here.
Information from this record has been curated, but not yet edited in PhosphoSitePlus® and may be incomplete.
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S172-p - IKKE (human)
Modsite: DDDEKFVsVYGTEEy SwissProt Entrez-Gene
Orthologous residues
IKKE (human): S172‑p, IKKE (mouse): S172‑p, IKKE (rat): S172‑p

S215-p - IRF1 (human)
Modsite: DLYNFQVsPMPsTsE SwissProt Entrez-Gene
Orthologous residues
IRF1 (human): S215‑p, IRF1 (mouse): S216‑p, IRF1 (rat): S216‑p
Upstream Regulation
Potential in vivo enzymes for site: 
Type Enzyme Evidence Notes
KINASE IKKE (human)

S219-p - IRF1 (human)
Modsite: FQVsPMPsTsEATTD SwissProt Entrez-Gene
Orthologous residues
IRF1 (human): S219‑p, IRF1 (mouse): S220‑p, IRF1 (rat): S220‑p
Upstream Regulation
Potential in vivo enzymes for site: 
Type Enzyme Evidence Notes
KINASE IKKE (human)

S221-p - IRF1 (human)
Modsite: VsPMPsTsEATTDED SwissProt Entrez-Gene
Orthologous residues
IRF1 (human): S221‑p, IRF1 (mouse): S222‑p, IRF1 (rat): S222‑p
Upstream Regulation
Potential in vivo enzymes for site: 
Type Enzyme Evidence Notes
KINASE IKKE (human)

S396-p - IRF3 (human)
Modsite: NtVDLHIsNsHPLsL SwissProt Entrez-Gene
Orthologous residues
IRF3 (human): S396‑p, IRF3 (mouse): S388‑p, IRF3 (rat): S390‑p

K310-ac - NFkB-p65 (human)
Modsite: KRtyEtFksIMkksP SwissProt Entrez-Gene
Orthologous residues
NFkB‑p65 (human): K310‑ac, NFkB‑p65 (mouse): K310‑ac, NFkB‑p65 (rat): K310‑ac