Curated Information
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Home > Curated Information Page > PubMed Id: 24425877
Calco GN, et al. (2014) CD2-associated protein (CD2AP) enhances casitas B lineage lymphoma-3/c (Cbl-3/c)-mediated Ret isoform-specific ubiquitination and degradation via its amino-terminal Src homology 3 domains. J Biol Chem 289, 7307-19 24425877
This page summarizes selected information from the record referenced above and curated into PhosphoSitePlus®, a comprehensive online resource for the study of protein post-translational modifications (NAR, 2015, 43:D512-20). To learn more about the scope of PhosphoSitePlus®, click here.
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Y341-p - Cbl-c (human)
Modsite: SEEQLQLyWAMDSTF SwissProt Entrez-Gene
Orthologous residues
Cbl‑c (human): Y341‑p, Cbl‑c (mouse): Y340‑p
Upstream Regulation
Potential in vivo enzymes for site: 
Type Enzyme Evidence Notes
KINASE Src (human)

K1060-ub - Ret (human)
Modsite: PSTWIENkLyGMsDP SwissProt Entrez-Gene
Orthologous residues
Ret (human): K1060‑ub, Ret iso2 (human): K1060‑ub, Ret iso3 (human): K584‑ub, Ret (mouse): K1061‑ub, Ret iso2 (mouse): K1061‑ub, Ret iso4 (mouse): , Ret (rat): K1061‑ub
Upstream Regulation
Potential in vivo enzymes for site: 
Type Enzyme Evidence Notes
UBIQUITIN LIGASE Cbl-c (human)

K1107-ub - Ret (human)
Modsite: MLSPSAAkLMDtFDs SwissProt Entrez-Gene
Orthologous residues
Ret (human): K1107‑ub, Ret iso2 (human): , Ret iso3 (human): , Ret (mouse): K1108‑ub, Ret iso2 (mouse): , Ret iso4 (mouse): , Ret (rat): K1108‑ub
Upstream Regulation
Potential in vivo enzymes for site: 
Type Enzyme Evidence Notes
UBIQUITIN LIGASE Cbl-c (human)