Adam-Stitah S, Penna L, Chambon P, Rochette-Egly C (1999) Hyperphosphorylation of the retinoid X receptor alpha by activated c-Jun NH2-terminal kinases. J Biol Chem 274, 18932-41 10383391

This page summarizes selected information from the record referenced above and curated into PhosphoSitePlus®, a comprehensive online resource for the study of protein post-translational modifications (NAR, 2015, 43:D512-20). To learn more about the scope of PhosphoSitePlus®, click here.

Click on the protein name to open the protein page, and on the RSD number to open the site page.

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S22-p - RXRA (mouse) ▲

Modsite: VNSSSLNsPTGRGSM SwissProt Entrez-Gene Orthologous residues RXRA (human): S21‑p, RXRA (mouse): S22‑p, RXRA (rat): S22‑p Characterization Methods used to characterize site in vivo:  [32P] bio-synthetic labeling, electrophoretic mobility shift, mutation of modification site, phosphopeptide mapping Relevant cell lines - cell types - tissues:  COS (fibroblast) Cellular systems studied:  cell lines Species studied:  green monkey

S61-p - RXRA (mouse) ▲

Modsite: SPISTLSsPINGMGP SwissProt Entrez-Gene Orthologous residues RXRA (human): S56‑p, RXRA (mouse): S61‑p, RXRA (rat): S61‑p Characterization Methods used to characterize site in vivo:  [32P] bio-synthetic labeling, electrophoretic mobility shift, mutation of modification site, phosphopeptide mapping Relevant cell lines - cell types - tissues:  COS (fibroblast) Cellular systems studied:  cell lines Species studied:  green monkey Upstream Regulation Potential in vivo enzymes for site:  Type Enzyme Evidence Notes KINASE JNK2 (mouse) transfection of wild-type enzyme KINASE JNK1 (mouse) transfection of wild-type enzyme Treatments, proteins and their effect on site modification:  Treatments Referenced Treatments Manipulated Protein Referenced Protein Effect Notes UV increase

S75-p - RXRA (mouse) ▲

Modsite: PPFSVISsPMGPHSM SwissProt Entrez-Gene Orthologous residues RXRA (human): S70‑p, RXRA (mouse): S75‑p, RXRA (rat): S75‑p Characterization Methods used to characterize site in vivo:  [32P] bio-synthetic labeling, electrophoretic mobility shift, mutation of modification site, phosphopeptide mapping Relevant cell lines - cell types - tissues:  COS (fibroblast) Cellular systems studied:  cell lines Species studied:  green monkey Upstream Regulation Potential in vivo enzymes for site:  Type Enzyme Evidence Notes KINASE JNK2 (mouse) transfection of wild-type enzyme KINASE JNK1 (mouse) transfection of wild-type enzyme Treatments, proteins and their effect on site modification:  Treatments Referenced Treatments Manipulated Protein Referenced Protein Effect Notes UV increase

T87-p - RXRA (mouse) ▲

Modsite: HSMSVPTtPTLGFGT SwissProt Entrez-Gene Orthologous residues RXRA (human): T82‑p, RXRA (mouse): T87‑p, RXRA (rat): T87‑p Characterization Methods used to characterize site in vivo:  [32P] bio-synthetic labeling, electrophoretic mobility shift, mutation of modification site, phosphopeptide mapping Relevant cell lines - cell types - tissues:  COS (fibroblast) Cellular systems studied:  cell lines Species studied:  green monkey Upstream Regulation Potential in vivo enzymes for site:  Type Enzyme Evidence Notes KINASE JNK2 (mouse) transfection of wild-type enzyme KINASE JNK1 (mouse) transfection of wild-type enzyme Treatments, proteins and their effect on site modification:  Treatments Referenced Treatments Manipulated Protein Referenced Protein Effect Notes UV increase

S265-p - RXRA (mouse) ▲

Modsite: NMGLNPSsPNDPVTN SwissProt Entrez-Gene Orthologous residues RXRA (human): S260‑p, RXRA (mouse): S265‑p, RXRA (rat): S265‑p Characterization Methods used to characterize site in vivo:  [32P] bio-synthetic labeling, electrophoretic mobility shift, mutation of modification site, phosphopeptide mapping Relevant cell lines - cell types - tissues:  COS (fibroblast) Cellular systems studied:  cell lines Species studied:  green monkey Upstream Regulation Potential in vivo enzymes for site:  Type Enzyme Evidence Notes KINASE JNK1 (mouse) transfection of wild-type enzyme KINASE JNK2 (mouse) transfection of wild-type enzyme Treatments, proteins and their effect on site modification:  Treatments Referenced Treatments Manipulated Protein Referenced Protein Effect Notes UV increase