Curated Information
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Home > Curated Information Page > PubMed Id: 14736917
Greif DM, Sacks DB, Michel T (2004) Calmodulin phosphorylation and modulation of endothelial nitric oxide synthase catalysis. Proc Natl Acad Sci U S A 101, 1165-70 14736917
This page summarizes selected information from the record referenced above and curated into PhosphoSitePlus®, a comprehensive online resource for the study of protein post-translational modifications (NAR, 2015, 43:D512-20). To learn more about the scope of PhosphoSitePlus®, click here.
Click on the protein name to open the protein page, and on the RSD number to open the site page.

T80-p - Calmodulin (rat)
Modsite: MARKMkDtDsEEEIR SwissProt Entrez-Gene
Orthologous residues
Calmodulin (human): T80‑p, Calmodulin (mouse): T80‑p, Calmodulin (rat): T80‑p, Calmodulin (chicken): T80‑p, Calmodulin (sheep): T80‑p, Calmodulin (cow): T80‑p

S82-p - Calmodulin (rat)
Modsite: RKMkDtDsEEEIREA SwissProt Entrez-Gene
Orthologous residues
Calmodulin (human): S82‑p, Calmodulin (mouse): S82‑p, Calmodulin (rat): S82‑p, Calmodulin (chicken): S82‑p, Calmodulin (sheep): S82‑p, Calmodulin (cow): S82‑p
Methods used to characterize site in vivo [32P] bio-synthetic labeling, mutation of modification site
Relevant cell lines - cell types - tissues:  BAEC (endothelial)
Cellular systems studied:  cell lines
Species studied:  cow
Enzymes shown to modify site in vitro
Type Enzyme
KINASE CK2A1 (rat)
Upstream Regulation
Potential in vivo enzymes for site: 
Type Enzyme Evidence Notes
KINASE CK2A1 (rat) pharmacological inhibitor of upstream enzyme
Treatments, proteins and their effect on site modification: 
Treatments Referenced Treatments Manipulated Protein Referenced Protein Effect Notes
DRB decrease
Downstream Regulation
Effect of modification (function):  phosphorylation

S102-p - Calmodulin (rat)
Modsite: kDGNGyIsAAELRHV SwissProt Entrez-Gene
Orthologous residues
Calmodulin (human): S102‑p, Calmodulin (mouse): S102‑p, Calmodulin (rat): S102‑p, Calmodulin (chicken): S102‑p, Calmodulin (sheep): S102‑p, Calmodulin (cow): S102‑p