Cheung HH, Teves L, Wallace MC, Gurd JW (2003) Inhibition of protein kinase C reduces ischemia-induced tyrosine phosphorylation of the N-methyl-d-aspartate receptor. J Neurochem 86, 1441-9 12950452

This page summarizes selected information from the record referenced above and curated into PhosphoSitePlus®, a comprehensive online resource for the study of protein post-translational modifications (NAR, 2015, 43:D512-20). To learn more about the scope of PhosphoSitePlus®, click here.

Click on the protein name to open the protein page, and on the RSD number to open the site page.

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Y1472-p - NMDAR2B (rat) ▲

Modsite: GSSNGHVyEKLssIE SwissProt Entrez-Gene Orthologous residues NMDAR2B (human): Y1474‑p, NMDAR2B (mouse): Y1472‑p, NMDAR2B (rat): Y1472‑p Characterization Methods used to characterize site in vivo:  phospho-antibody, western blotting Cellular systems studied:  tissue Species studied:  rat Upstream Regulation Treatments, proteins and their effect on site modification:  Treatments Referenced Treatments Manipulated Protein Referenced Protein Effect Notes ischemia/reperfusion increase GF109203X ischemia/reperfusion inhibit treatment-induced increase PP2 ischemia/reperfusion inhibit treatment-induced increase calphostin_C ischemia/reperfusion inhibit treatment-induced increase

Y402-p - Pyk2 (rat) ▲

Modsite: CSIESDIyAEIPDET SwissProt Entrez-Gene Orthologous residues Pyk2 (human): Y402‑p, Pyk2 iso2 (human): Y402‑p, Pyk2 (mouse): Y402‑p, Pyk2 (rat): Y402‑p Characterization Methods used to characterize site in vivo:  phospho-antibody, western blotting Cellular systems studied:  tissue Species studied:  rat Upstream Regulation Treatments, proteins and their effect on site modification:  Treatments Referenced Treatments Manipulated Protein Referenced Protein Effect Notes ischemia increase GF109203X ischemia inhibit treatment-induced increase

Y419-p - Src (rat) ▲

Modsite: RLIEDNEyTARQGAk SwissProt Entrez-Gene Orthologous residues Src (human): Y419‑p, Src iso2 (human): Y425‑p, Src (mouse): Y418‑p, Src iso1 (mouse): Y424‑p, Src (rat): Y419‑p, Src (chicken): Y416‑p Characterization Methods used to characterize site in vivo:  phospho-antibody, western blotting Cellular systems studied:  tissue Species studied:  rat Upstream Regulation Treatments, proteins and their effect on site modification:  Treatments Referenced Treatments Manipulated Protein Referenced Protein Effect Notes ischemia increase GF109203X ischemia inhibit treatment-induced increase