Omata W, Ackerman WE, Vandre DD, Robinson JM (2013) Trophoblast cell fusion and differentiation are mediated by both the protein kinase C and a pathways. PLoS One 8, e81003 24236208

This page summarizes selected information from the record referenced above and curated into PhosphoSitePlus®, a comprehensive online resource for the study of protein post-translational modifications (NAR, 2015, 43:D512-20). To learn more about the scope of PhosphoSitePlus®, click here.

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S660-p - PKCB iso2 (human) ▲

Modsite: QsEFEGFsFVNsEFL SwissProt Entrez-Gene Orthologous residues PKCB (human): ‑, PKCB iso2 (human): S660‑p, PKCB (mouse): ‑, PKCB iso2 (mouse): S660‑p, PKCB (rat): ‑, PKCB iso2 (rat): S660‑p, PKCB (cow): S660‑p Characterization Methods used to characterize site in vivo:  electrophoretic mobility shift, phospho-antibody, western blotting Disease tissue studied:  urethral cancer Relevant cell lines - cell types - tissues:  BeWo Cellular systems studied:  cell lines Species studied:  human Upstream Regulation Treatments, proteins and their effect on site modification:  Treatments Referenced Treatments Manipulated Protein Referenced Protein Effect Notes phorbol_ester increase 4alphaPMA no change compared to control Downstream Regulation Effect of modification (function):  enzymatic activity, induced, intracellular localization

S645-p - PKCD (human) ▲

Modsite: LNEkARLsysDKNLI SwissProt Entrez-Gene Orthologous residues PKCD (human): S645‑p, PKCD iso2 (human): S676‑p, PKCD (mouse): S643‑p, PKCD iso2 (mouse): S669‑p, PKCD (rat): S643‑p Characterization Methods used to characterize site in vivo:  electrophoretic mobility shift, phospho-antibody, western blotting Disease tissue studied:  urethral cancer Relevant cell lines - cell types - tissues:  BeWo Cellular systems studied:  cell lines Species studied:  human Upstream Regulation Treatments, proteins and their effect on site modification:  Treatments Referenced Treatments Manipulated Protein Referenced Protein Effect Notes phorbol_ester increase 4alphaPMA no change compared to control