Curated Information
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Home > Curated Information Page > PubMed Id: 24236208
Omata W, Ackerman WE, Vandre DD, Robinson JM (2013) Trophoblast cell fusion and differentiation are mediated by both the protein kinase C and a pathways. PLoS One 8, e81003 24236208
This page summarizes selected information from the record referenced above and curated into PhosphoSitePlus®, a comprehensive online resource for the study of protein post-translational modifications (NAR, 2015, 43:D512-20). To learn more about the scope of PhosphoSitePlus®, click here.
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S660-p - PKCB iso2 (human)
Modsite: QsEFEGFsFVNsEFL SwissProt Entrez-Gene
Orthologous residues
PKCB (human): , PKCB iso2 (human): S660‑p, PKCB (mouse): , PKCB iso2 (mouse): S660‑p, PKCB (rat): , PKCB iso2 (rat): S660‑p, PKCB (cow): S660‑p
Characterization
Methods used to characterize site in vivo electrophoretic mobility shift, phospho-antibody, western blotting
Disease tissue studied:  urethral cancer
Relevant cell lines - cell types - tissues:  BeWo
Cellular systems studied:  cell lines
Species studied:  human
Upstream Regulation
Treatments, proteins and their effect on site modification: 
Treatments Referenced Treatments Manipulated Protein Referenced Protein Effect Notes
phorbol_ester increase
4alphaPMA no change compared to control
Downstream Regulation
Effect of modification (function):  enzymatic activity, induced, intracellular localization

S645-p - PKCD (human)
Modsite: LNEkARLsysDKNLI SwissProt Entrez-Gene
Orthologous residues
PKCD (human): S645‑p, PKCD iso2 (human): S676‑p, PKCD (mouse): S643‑p, PKCD iso2 (mouse): S669‑p, PKCD (rat): S643‑p
Characterization
Methods used to characterize site in vivo electrophoretic mobility shift, phospho-antibody, western blotting
Disease tissue studied:  urethral cancer
Relevant cell lines - cell types - tissues:  BeWo
Cellular systems studied:  cell lines
Species studied:  human
Upstream Regulation
Treatments, proteins and their effect on site modification: 
Treatments Referenced Treatments Manipulated Protein Referenced Protein Effect Notes
phorbol_ester increase
4alphaPMA no change compared to control