Curated Information
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Home > Curated Information Page > PubMed Id: 14680817
Ding J, Soule G, Overmeyer JH, Maltese WA (2003) Tyrosine phosphorylation of the Rab24 GTPase in cultured mammalian cells. Biochem Biophys Res Commun 312, 670-5 14680817
This page summarizes selected information from the record referenced above and curated into PhosphoSitePlus®, a comprehensive online resource for the study of protein post-translational modifications (NAR, 2015, 43:D512-20). To learn more about the scope of PhosphoSitePlus®, click here.
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Y17-p - RAB24 (mouse)
Modsite: VVMLGKEyVGKTSLV SwissProt Entrez-Gene
Orthologous residues
RAB24 (human): Y17‑p, RAB24 (mouse): Y17‑p, RAB24 (rat): Y17‑p
Characterization
Methods used to characterize site in vivo mutation of modification site, phospho-antibody, western blotting
Disease tissue studied:  oropharyngeal cancer, squamous cell carcinoma of the oropharynx
Relevant cell lines - cell types - tissues:  293 (epithelial), HEp-2 (squamous)
Cellular systems studied:  cell lines
Species studied:  human
Upstream Regulation
Treatments, proteins and their effect on site modification: 
Treatments Referenced Treatments Manipulated Protein Referenced Protein Effect Notes
genistein decrease
PP2 decrease
tyrphostin_25A no change compared to control

Y172-p - RAB24 (mouse)
Modsite: FQKVAEDyVSVAAFQ SwissProt Entrez-Gene
Orthologous residues
RAB24 (human): Y172‑p, RAB24 (mouse): Y172‑p, RAB24 (rat): Y172‑p
Characterization
Methods used to characterize site in vivo mutation of modification site, phospho-antibody, western blotting
Disease tissue studied:  oropharyngeal cancer, squamous cell carcinoma of the oropharynx
Relevant cell lines - cell types - tissues:  293 (epithelial), HEp-2 (squamous)
Cellular systems studied:  cell lines
Species studied:  human
Upstream Regulation
Treatments, proteins and their effect on site modification: 
Treatments Referenced Treatments Manipulated Protein Referenced Protein Effect Notes
genistein decrease
PP2 decrease
tyrphostin_25A no change compared to control