Curated Information
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Home > Curated Information Page > PubMed Id: 18498750
Gorski SA, et al. (2008) Modulation of RNA polymerase assembly dynamics in transcriptional regulation. Mol Cell 30, 486-97 18498750
This page summarizes selected information from the record referenced above and curated into PhosphoSitePlus®, a comprehensive online resource for the study of protein post-translational modifications (NAR, 2015, 43:D512-20). To learn more about the scope of PhosphoSitePlus®, click here.
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S649-p - TIF1A (human)
Modsite: PVLYMQPsPL_____ SwissProt Entrez-Gene
Orthologous residues
TIF1A (human): S649‑p, TIF1A (mouse): S648‑p
Characterization
Methods used to characterize site in vivo immunoprecipitation, mutation of modification site
Relevant cell lines - cell types - tissues:  HeLa (cervical), Tr9-7 (fibroblast)
Cellular systems studied:  cell lines
Species studied:  human
Downstream Regulation
Effect of modification (function):  molecular association, regulation
Effect of modification (process):  cell cycle regulation, transcription, induced
Modification regulates interactions with: 
Interacting molecule Interacting domains Effect Consequences (function) Consequences (process) Detection assays
POLR2F (human) Induces co-immunoprecipitation, microscopy-colocalization