Curated Information
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Home > Curated Information Page > PubMed Id: 23882217
Jeyaraman MM, Fandrich RR, Kardami E (2013) Together and apart: inhibition of DNA synthesis by connexin-43 and its relationship to transforming growth factor β. Front Pharmacol 4, 90 23882217
This page summarizes selected information from the record referenced above and curated into PhosphoSitePlus®, a comprehensive online resource for the study of protein post-translational modifications (NAR, 2015, 43:D512-20). To learn more about the scope of PhosphoSitePlus®, click here.
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S262-p - GJA1 (rat)
Modsite: sPskDCGsPkyAyFN SwissProt Entrez-Gene
Orthologous residues
GJA1 (human): S262‑p, GJA1 (mouse): S262‑p, GJA1 (rat): S262‑p, GJA1 (rabbit): S262‑p, GJA1 (pig): S262‑p, GJA1 (hamster): S262‑p, GJA1 (cow): S263‑p
Characterization
Methods used to characterize site in vivo mutation of modification site, phospho-antibody, western blotting
Relevant cell lines - cell types - tissues:  myocyte-heart
Cellular systems studied:  primary cultured cells
Species studied:  rat
Upstream Regulation
Treatments, proteins and their effect on site modification: 
Treatments Referenced Treatments Manipulated Protein Referenced Protein Effect Notes
FGF2 increase
TGF-beta FGF2 inhibit treatment-induced increase
SB431542 increase
TGFBR2 (rat) decrease
Downstream Regulation
Effect of modification (process):  cell cycle regulation, cell growth, induced, signaling pathway regulation