Curated Information
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Home > Curated Information Page > PubMed Id: 28958480
Han KH, et al. (2017) Protein profiling and angiogenic effect of hypoxia-cultured human umbilical cord blood-derived mesenchymal stem cells in hindlimb ischemia. Tissue Cell 49, 680-690 28958480
This page summarizes selected information from the record referenced above and curated into PhosphoSitePlus®, a comprehensive online resource for the study of protein post-translational modifications (NAR, 2015, 43:D512-20). To learn more about the scope of PhosphoSitePlus®, click here.
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S65-p - 4E-BP1 (human)
Modsite: FLMECrNsPVtktPP SwissProt Entrez-Gene
Orthologous residues
4E‑BP1 (human): S65‑p, 4E‑BP1 (mouse): S64‑p, 4E‑BP1 (rat): S64‑p, 4E‑BP1 (fruit fly): S65‑p, 4E‑BP1 (cow): S65‑p
Characterization
Methods used to characterize site in vivo phospho-antibody
Relevant cell lines - cell types - tissues:  hUCB-MSCs
Cellular systems studied:  primary cultured cells
Species studied:  human
Upstream Regulation
Treatments, proteins and their effect on site modification: 
Treatments Referenced Treatments Manipulated Protein Referenced Protein Effect Notes
hypoxia increase

Y185-p - Abl (human)
Modsite: TAsDGKLyVsSESRF SwissProt Entrez-Gene
Orthologous residues
Abl (human): Y185‑p, Abl iso2 (human): Y204‑p, Abl (mouse): Y185‑p, Abl iso4 (mouse): Y204‑p, Abl (rat): Y185‑p, Abl iso2 (rat): Y204‑p
Characterization
Methods used to characterize site in vivo phospho-antibody
Relevant cell lines - cell types - tissues:  hUCB-MSCs
Cellular systems studied:  primary cultured cells
Species studied:  human
Upstream Regulation
Treatments, proteins and their effect on site modification: 
Treatments Referenced Treatments Manipulated Protein Referenced Protein Effect Notes
hypoxia increase

T47-p - Bcl-xL (human)
Modsite: GTESEMEtPsAINGN SwissProt Entrez-Gene
Orthologous residues
Bcl‑xL (human): T47‑p, Bcl‑xL (mouse): T47‑p, Bcl‑xL (rat): T47‑p
Characterization
Methods used to characterize site in vivo phospho-antibody
Relevant cell lines - cell types - tissues:  hUCB-MSCs
Cellular systems studied:  primary cultured cells
Species studied:  human

T2647-p - DNAPK (human)
Modsite: QQHDFtLtQTADGRs SwissProt Entrez-Gene
Orthologous residues
DNAPK (human): T2647‑p, DNAPK iso2 (human): T2647‑p, DNAPK (mouse): T2643‑p, DNAPK (rat): T2641‑p
Characterization
Methods used to characterize site in vivo phospho-antibody
Relevant cell lines - cell types - tissues:  hUCB-MSCs
Cellular systems studied:  primary cultured cells
Species studied:  human
Upstream Regulation
Treatments, proteins and their effect on site modification: 
Treatments Referenced Treatments Manipulated Protein Referenced Protein Effect Notes
hypoxia decrease

Y40-p - Etk (human)
Modsite: LTKTNLSyYEYDKMK SwissProt Entrez-Gene
Orthologous residues
Etk (human): Y40‑p, Etk (mouse): Y40‑p
Characterization
Methods used to characterize site in vivo phospho-antibody
Relevant cell lines - cell types - tissues:  hUCB-MSCs
Cellular systems studied:  primary cultured cells
Species studied:  human

Y508-p - LYN (human)
Modsite: ytAtEGQyQQQP___ SwissProt Entrez-Gene
Orthologous residues
LYN (human): Y508‑p, LYN iso2 (human): Y487‑p, LYN (mouse): Y508‑p, LYN iso2 (mouse): Y487‑p, LYN (rat): Y508‑p
Characterization
Methods used to characterize site in vivo phospho-antibody
Relevant cell lines - cell types - tissues:  hUCB-MSCs
Cellular systems studied:  primary cultured cells
Species studied:  human
Upstream Regulation
Treatments, proteins and their effect on site modification: 
Treatments Referenced Treatments Manipulated Protein Referenced Protein Effect Notes
hypoxia decrease

T538-p - PKCT (human)
Modsite: LGDAktNtFCGtPDy SwissProt Entrez-Gene
Orthologous residues
PKCT (human): T538‑p, PKCT (mouse): T538‑p, PKCT (rat): T538‑p
Characterization
Methods used to characterize site in vivo phospho-antibody
Relevant cell lines - cell types - tissues:  hUCB-MSCs
Cellular systems studied:  primary cultured cells
Species studied:  human
Upstream Regulation
Treatments, proteins and their effect on site modification: 
Treatments Referenced Treatments Manipulated Protein Referenced Protein Effect Notes
hypoxia decrease

S62-p - SYN1 (human)
Modsite: SGVAPAAsPAAPsPG SwissProt Entrez-Gene
Orthologous residues
SYN1 (human): S62‑p, SYN1 iso2 (human): S62‑p, SYN1 (mouse): S62‑p, SYN1 iso1 (mouse): S62‑p, SYN1 iso3 (mouse): S62‑p, SYN1 (rat): S62‑p, SYN1 (cow): S62‑p
Characterization
Methods used to characterize site in vivo phospho-antibody
Relevant cell lines - cell types - tissues:  hUCB-MSCs
Cellular systems studied:  primary cultured cells
Species studied:  human
Upstream Regulation
Treatments, proteins and their effect on site modification: 
Treatments Referenced Treatments Manipulated Protein Referenced Protein Effect Notes
hypoxia increase

Y951-p - VEGFR2 (human)
Modsite: RFRQGKDyVGAIPVD SwissProt Entrez-Gene
Orthologous residues
VEGFR2 (human): Y951‑p, VEGFR2 (mouse): Y949‑p, VEGFR2 (rat): Y947‑p
Characterization
Methods used to characterize site in vivo phospho-antibody
Relevant cell lines - cell types - tissues:  hUCB-MSCs
Cellular systems studied:  primary cultured cells
Species studied:  human
Upstream Regulation
Treatments, proteins and their effect on site modification: 
Treatments Referenced Treatments Manipulated Protein Referenced Protein Effect Notes
hypoxia increase