Curated Information
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Home > Curated Information Page > PubMed Id: 23292070
Monteserin-Garcia J, et al. (2013) Sirt1 inhibits the transcription factor CREB to regulate pituitary growth hormone synthesis. FASEB J 27, 1561-71 23292070
This page summarizes selected information from the record referenced above and curated into PhosphoSitePlus®, a comprehensive online resource for the study of protein post-translational modifications (NAR, 2015, 43:D512-20). To learn more about the scope of PhosphoSitePlus®, click here.
Information from this record has been curated, but not yet edited in PhosphoSitePlus® and may be incomplete.
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K205-ac - GSK3B (rat)
Modsite: LCDFGSAkQLVRGEP SwissProt Entrez-Gene
Orthologous residues
GSK3B (human): K205‑ac, GSK3B iso2 (human): K205‑ac, GSK3B (mouse): K205‑ac, GSK3B (rat): K205‑ac, GSK3B (rabbit): K205‑ac

S641-p - GYS1 (rat)
Modsite: YRYPRPAsVPPsPSL SwissProt Entrez-Gene
Orthologous residues
GYS1 (human): S641‑p, GYS1 iso2 (human): S577‑p, GYS1 (mouse): S641‑p, GYS1 (rat): S641‑p, GYS1 (rabbit): S641‑p

S2481-p - mTOR (rat)
Modsite: TVPEsIHsFIGDGLV SwissProt Entrez-Gene
Orthologous residues
mTOR (human): S2481‑p, mTOR (mouse): S2481‑p, mTOR (rat): S2481‑p
Upstream Regulation
Treatments, proteins and their effect on site modification: 
Treatments Referenced Treatments Manipulated Protein Referenced Protein Effect Notes
resveratrol decrease

T389-p - p70S6K iso2 (rat)
Modsite: NQVFLGFtYVAPSVL SwissProt Entrez-Gene
Orthologous residues
p70S6K (human): T412‑p, p70S6K iso2 (human): T389‑p, p70S6K (mouse): T412‑p, p70S6K (rat): T412‑p, p70S6K iso2 (rat): T389‑p, p70S6K (fruit fly): T398‑p

T73-p - PPP1R2 (rat)
Modsite: MKIDEPDtPYHNMIG SwissProt Entrez-Gene
Orthologous residues
PPP1R2 (human): T73‑p, PPP1R2 (mouse): T74‑p, PPP1R2 (rat): T73‑p, PPP1R2 (rabbit): T73‑p