Curated Information
Javascript is not enabled on this browser. This site will not work properly without Javascript.
PhosphoSitePlus Homepage PhosphoSitePlus® v6.5.9.2
Powered by Cell Signaling Technology
Home > Curated Information Page > PubMed Id: 17218276
Geng Y, et al. (2007) Kinase-independent function of cyclin E. Mol Cell 25, 127-39 17218276
This page summarizes selected information from the record referenced above and curated into PhosphoSitePlus®, a comprehensive online resource for the study of protein post-translational modifications (NAR, 2015, 43:D512-20). To learn more about the scope of PhosphoSitePlus®, click here.
Click on the protein name to open the protein page, and on the RSD number to open the site page.
Download

S90-p - CCNE1 (human)
Modsite: DDRVYPNsTCKPRII SwissProt Entrez-Gene
Orthologous residues
CCNE1 (human): S90‑p, CCNE1 (mouse): T88‑p, CCNE1 (rat): T91‑p
Characterization
Methods used to characterize site in vivo mutation of modification site
Relevant cell lines - cell types - tissues:  MEF (fibroblast), MEF (fibroblast) [CCNE1 (human)]
Cellular systems studied:  cell lines
Species studied:  mouse

S399-p - CCNE1 (human)
Modsite: GLLtPPQsGKKQSSG SwissProt Entrez-Gene
Orthologous residues
CCNE1 (human): S399‑p, CCNE1 (mouse): S397‑p, CCNE1 (rat): S400‑p
Characterization
Methods used to characterize site in vivo phospho-antibody, western blotting
Relevant cell lines - cell types - tissues:  293 (epithelial)
Cellular systems studied:  cell lines
Upstream Regulation
Potential in vivo enzymes for site: 
Type Enzyme Evidence Notes
KINASE CDK2 (human) transfection of wild-type enzyme, phospho-antibody, transfection of dominant-negative enzyme

S54-p - CDC6 (human)
Modsite: RVkALPLsPRKRLGD SwissProt Entrez-Gene
Orthologous residues
CDC6 (human): S54‑p, CDC6 (mouse): S55‑p, CDC6 (hamster): S55‑p