Curated Information
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Home > Curated Information Page > PubMed Id: 22504297
Choi Y, Kang D, Han IO, Oh ES (2012) Hierarchy between the transmembrane and cytoplasmic domains in the regulation of syndecan-4 functions. Cell Signal 24, 1522-30 22504297
This page summarizes selected information from the record referenced above and curated into PhosphoSitePlus®, a comprehensive online resource for the study of protein post-translational modifications (NAR, 2015, 43:D512-20). To learn more about the scope of PhosphoSitePlus®, click here.
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S183-p - syndecan-4 (rat)
Modsite: MKKKDEGsYDLGKKP SwissProt Entrez-Gene
Orthologous residues
syndecan‑4 (human): S179‑p, syndecan‑4 (mouse): S179‑p, syndecan‑4 (rat): S183‑p
Characterization
Methods used to characterize site in vivo mutation of modification site, western blotting
Relevant cell lines - cell types - tissues:  REF (fibroblast)
Cellular systems studied:  cell lines
Species studied:  rat
Downstream Regulation
Effect of modification (function):  protein conformation
Effect of modification (process):  cell adhesion, induced, cell motility, inhibited
Comments:  decreased Rho A activation