Curated Information
Javascript is not enabled on this browser. This site will not work properly without Javascript.
PhosphoSitePlus Homepage PhosphoSitePlus® v6.5.9.3
Powered by Cell Signaling Technology
Home > Curated Information Page > PubMed Id: 22846565
Hossain Khan MZ, et al. (2012) Phosphorylation of Na-Cl cotransporter by OSR1 and SPAK kinases regulates its ubiquitination. Biochem Biophys Res Commun 425, 456-61 22846565
This page summarizes selected information from the record referenced above and curated into PhosphoSitePlus®, a comprehensive online resource for the study of protein post-translational modifications (NAR, 2015, 43:D512-20). To learn more about the scope of PhosphoSitePlus®, click here.
Information from this record has been curated, but not yet edited in PhosphoSitePlus® and may be incomplete.
Click on the protein name to open the protein page, and on the RSD number to open the site page.
Download

T53-p - NCCT (mouse)
Modsite: GstLyMRtFGYNtID SwissProt Entrez-Gene
Orthologous residues
NCCT (human): T55‑p, NCCT iso2 (human): T55‑p, NCCT iso3 (human): T55‑p, NCCT (mouse): T53‑p, NCCT (rat): T53‑p
Characterization
Methods used to characterize site in vivo mutation of modification site
Relevant cell lines - cell types - tissues:  COS7 (fibroblast)
Cellular systems studied:  cell lines
Species studied:  green monkey
Downstream Regulation
Effect of modification (function):  ubiquitination
Comments:  ubiquitination decreased

T58-p - NCCT (mouse)
Modsite: MRtFGYNtIDVVPAY SwissProt Entrez-Gene
Orthologous residues
NCCT (human): T60‑p, NCCT iso2 (human): T60‑p, NCCT iso3 (human): T60‑p, NCCT (mouse): T58‑p, NCCT (rat): T58‑p
Characterization
Methods used to characterize site in vivo mutation of modification site
Relevant cell lines - cell types - tissues:  COS7 (fibroblast)
Cellular systems studied:  cell lines
Species studied:  green monkey
Downstream Regulation
Effect of modification (function):  ubiquitination
Comments:  ubiquitination decreased

S71-p - NCCT (mouse)
Modsite: AYEHYANsALPGEPR SwissProt Entrez-Gene
Orthologous residues
NCCT (human): S73‑p, NCCT iso2 (human): S73‑p, NCCT iso3 (human): S73‑p, NCCT (mouse): S71‑p, NCCT (rat): S71‑p
Characterization
Methods used to characterize site in vivo mutation of modification site
Relevant cell lines - cell types - tissues:  COS7 (fibroblast)
Cellular systems studied:  cell lines
Species studied:  green monkey
Downstream Regulation
Effect of modification (function):  ubiquitination
Comments:  ubiquitination decreased