Curated Information
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Home > Curated Information Page > PubMed Id: 22729691
Dyce PW, Norris RP, Lampe PD, Kidder GM (2012) Phosphorylation of Serine Residues in the C-terminal Cytoplasmic Tail of Connexin43 Regulates Proliferation of Ovarian Granulosa Cells. J Membr Biol 245, 291-301 22729691
This page summarizes selected information from the record referenced above and curated into PhosphoSitePlus®, a comprehensive online resource for the study of protein post-translational modifications (NAR, 2015, 43:D512-20). To learn more about the scope of PhosphoSitePlus®, click here.
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S255-p - GJA1 (mouse)
Modsite: HAtTGPLsPskDCGs SwissProt Entrez-Gene
Orthologous residues
GJA1 (human): S255‑p, GJA1 (mouse): S255‑p, GJA1 (rat): S255‑p, GJA1 (rabbit): S255‑p, GJA1 (pig): S255‑p, GJA1 (hamster): N255‑p, GJA1 (cow): S256‑p
Characterization
Methods used to characterize site in vivo mutation of modification site
Relevant cell lines - cell types - tissues:  oocyte, ovary
Cellular systems studied:  primary cultured cells
Species studied:  mouse

S262-p - GJA1 (mouse)
Modsite: sPskDCGsPkyAyFN SwissProt Entrez-Gene
Orthologous residues
GJA1 (human): S262‑p, GJA1 (mouse): S262‑p, GJA1 (rat): S262‑p, GJA1 (rabbit): S262‑p, GJA1 (pig): S262‑p, GJA1 (hamster): S262‑p, GJA1 (cow): S263‑p
Characterization
Methods used to characterize site in vivo mutation of modification site
Relevant cell lines - cell types - tissues:  oocyte, ovary
Cellular systems studied:  primary cultured cells
Species studied:  mouse

S279-p - GJA1 (mouse)
Modsite: SsPtAPLsPMsPPGy SwissProt Entrez-Gene
Orthologous residues
GJA1 (human): S279‑p, GJA1 (mouse): S279‑p, GJA1 (rat): S279‑p, GJA1 (rabbit): S279‑p, GJA1 (pig): S279‑p, GJA1 (hamster): S279‑p, GJA1 (cow): S280‑p
Characterization
Methods used to characterize site in vivo immunoassay, mutation of modification site
Relevant cell lines - cell types - tissues:  oocyte, ovary
Cellular systems studied:  primary cultured cells
Species studied:  mouse
Downstream Regulation
Effect of modification (function):  intracellular localization
Effect of modification (process):  cell growth, induced

S282-p - GJA1 (mouse)
Modsite: tAPLsPMsPPGykLV SwissProt Entrez-Gene
Orthologous residues
GJA1 (human): S282‑p, GJA1 (mouse): S282‑p, GJA1 (rat): S282‑p, GJA1 (rabbit): S282‑p, GJA1 (pig): S282‑p, GJA1 (hamster): S282‑p, GJA1 (cow): S283‑p
Characterization
Methods used to characterize site in vivo immunoassay, mutation of modification site
Relevant cell lines - cell types - tissues:  oocyte, ovary
Cellular systems studied:  primary cultured cells
Species studied:  mouse
Downstream Regulation
Effect of modification (function):  intracellular localization
Effect of modification (process):  cell growth, induced