Curated Information
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Home > Curated Information Page > PubMed Id: 22726831
Sandoz G, Levitz J, Kramer RH, Isacoff EY (2012) Optical Control of Endogenous Proteins with a Photoswitchable Conditional Subunit Reveals a Role for TREK1 in GABA(B) Signaling. Neuron 74, 1005-14 22726831
This page summarizes selected information from the record referenced above and curated into PhosphoSitePlus®, a comprehensive online resource for the study of protein post-translational modifications (NAR, 2015, 43:D512-20). To learn more about the scope of PhosphoSitePlus®, click here.
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S348-p - TREK-1 (human)
Modsite: KETRRRLsVEIYDKF SwissProt Entrez-Gene
Orthologous residues
TREK‑1 (human): S348‑p, TREK‑1 iso2 (human): S333‑p, TREK‑1 iso3 (human): S344‑p, TREK‑1 (mouse): S348‑p
Methods used to characterize site in vivo mutation of modification site
Relevant cell lines - cell types - tissues:  293 (epithelial)
Cellular systems studied:  cell lines
Species studied:  human
Downstream Regulation
Effect of modification (function):  activity, inhibited
Comments:  current reduced by phosphorylation