Cooper CD, Lampe PD (2002) Casein kinase 1 regulates connexin-43 gap junction assembly. J Biol Chem 277, 44962-8 12270943

This page summarizes selected information from the record referenced above and curated into PhosphoSitePlus®, a comprehensive online resource for the study of protein post-translational modifications (NAR, 2015, 43:D512-20). To learn more about the scope of PhosphoSitePlus®, click here.

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S325-p - GJA1 (rat) ▲

Modsite: NRMGQAGstIsNsHA SwissProt Entrez-Gene Orthologous residues GJA1 (human): S325‑p, GJA1 (mouse): S325‑p, GJA1 (rat): S325‑p, GJA1 (rabbit): S325‑p, GJA1 (pig): S325‑p, GJA1 (hamster): S325‑p, GJA1 (cow): S326‑p Characterization Methods used to characterize site in vivo:  [32P] bio-synthetic labeling, mass spectrometry Relevant cell lines - cell types - tissues:  NRK (fibroblast) Cellular systems studied:  cell lines Species studied:  rat Enzymes shown to modify site in vitro:  Type Enzyme KINASE CK1A (human) Upstream Regulation Potential in vivo enzymes for site:  Type Enzyme Evidence Notes KINASE CK1A (human) pharmacological inhibitor of upstream enzyme, co-immunoprecipitation Downstream Regulation Effect of modification (function):  intracellular localization Effect of modification (process):  cell adhesion, altered

S328-p - GJA1 (rat) ▲

Modsite: GQAGstIsNsHAQPF SwissProt Entrez-Gene Orthologous residues GJA1 (human): S328‑p, GJA1 (mouse): S328‑p, GJA1 (rat): S328‑p, GJA1 (rabbit): S328‑p, GJA1 (pig): S328‑p, GJA1 (hamster): S328‑p, GJA1 (cow): S329‑p Characterization Methods used to characterize site in vivo:  [32P] bio-synthetic labeling, mass spectrometry Relevant cell lines - cell types - tissues:  NRK (fibroblast) Cellular systems studied:  cell lines Species studied:  rat Enzymes shown to modify site in vitro:  Type Enzyme KINASE CK1A (human) Upstream Regulation Potential in vivo enzymes for site:  Type Enzyme Evidence Notes KINASE CK1A (human) pharmacological inhibitor of upstream enzyme, co-immunoprecipitation Downstream Regulation Effect of modification (function):  intracellular localization Effect of modification (process):  cell adhesion, altered

S330-p - GJA1 (rat) ▲

Modsite: AGstIsNsHAQPFDF SwissProt Entrez-Gene Orthologous residues GJA1 (human): S330‑p, GJA1 (mouse): S330‑p, GJA1 (rat): S330‑p, GJA1 (rabbit): S330‑p, GJA1 (pig): S330‑p, GJA1 (hamster): S330‑p, GJA1 (cow): S331‑p Characterization Methods used to characterize site in vivo:  [32P] bio-synthetic labeling, mass spectrometry Relevant cell lines - cell types - tissues:  NRK (fibroblast) Cellular systems studied:  cell lines Species studied:  rat Enzymes shown to modify site in vitro:  Type Enzyme KINASE CK1A (human) Upstream Regulation Potential in vivo enzymes for site:  Type Enzyme Evidence Notes KINASE CK1A (human) pharmacological inhibitor of upstream enzyme, co-immunoprecipitation Downstream Regulation Effect of modification (function):  intracellular localization Effect of modification (process):  cell adhesion, altered