Helling S, et al. (2012) Multiple phosphorylations of cytochrome c oxidase and their functions. Proteomics 12, 950-9 22522801

This page summarizes selected information from the record referenced above and curated into PhosphoSitePlus®, a comprehensive online resource for the study of protein post-translational modifications (NAR, 2015, 43:D512-20). To learn more about the scope of PhosphoSitePlus®, click here.

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S126-p - COX2 (cow) ▲
Modsite: DSYMIPTsELKPGEL SwissProt Entrez-Gene Orthologous residues COX2 (human): L126‑p, COX2 (mouse): N126‑p, COX2 (rat): N126‑p, COX2 (cow): S126‑p Characterization Methods used to characterize site in vivo:  mass spectrometry Relevant cell lines - cell types - tissues:  heart Cellular systems studied:  tissue Species studied:  cow

Y218-p - COX2 (cow) ▲
Modsite: LELVPLKyFEKWSAS SwissProt Entrez-Gene Orthologous residues COX2 (human): I218‑p, COX2 (mouse): Y218‑p, COX2 (rat): Y218‑p, COX2 (cow): Y218‑p Characterization Methods used to characterize site in vivo:  mass spectrometry Relevant cell lines - cell types - tissues:  heart Cellular systems studied:  tissue Species studied:  cow

S44-p - COX5A (cow) ▲
Modsite: VQSLRCYsHGsHETD SwissProt Orthologous residues COX5A (human): S42‑p, COX5A (mouse): S38‑p, COX5A (rat): S38‑p, COX5A (cow): S44‑p Characterization Methods used to characterize site in vivo:  mass spectrometry Relevant cell lines - cell types - tissues:  heart Cellular systems studied:  tissue Species studied:  cow

S47-p - COX5A (cow) ▲
Modsite: LRCYsHGsHETDEEF SwissProt Orthologous residues COX5A (human): S45‑p, COX5A (mouse): S41‑p, COX5A (rat): S41‑p, COX5A (cow): S47‑p Characterization Methods used to characterize site in vivo:  mass spectrometry Relevant cell lines - cell types - tissues:  heart Cellular systems studied:  tissue Species studied:  cow

S33-p - COX5B (cow) ▲

Modsite: SVVRSMAsGGGVPTD SwissProt Orthologous residues COX5B (human): S33‑p, COX5B (mouse): S32‑p, COX5B (rat): S33‑p, COX5B (rabbit): S33‑p, COX5B (pig): S33‑p, COX5B (cow): S33‑p Characterization Methods used to characterize site in vivo:  mass spectrometry Relevant cell lines - cell types - tissues:  heart Cellular systems studied:  tissue Species studied:  cow Downstream Regulation Effect of modification (function):  enzymatic activity, inhibited

S17-p - COX7C (cow) ▲
Modsite: TTSVVRRsHYEEGPG SwissProt Entrez-Gene Orthologous residues COX7C (human): S17‑p, COX7C (mouse): S17‑p, COX7C (rat): S17‑p, COX7C (cow): S17‑p Characterization Methods used to characterize site in vivo:  mass spectrometry Relevant cell lines - cell types - tissues:  heart Cellular systems studied:  tissue Species studied:  cow