Sordella R, et al. (2003) Modulation of Rho GTPase signaling regulates a switch between adipogenesis and myogenesis. Cell 113, 147-58 12705864

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Y306-p - ARHGAP5 (human) ▲

Modsite: NHPDYEEyINLEGTR SwissProt Entrez-Gene Orthologous residues ARHGAP5 (human): Y306‑p, ARHGAP5 iso2 (human): Y306‑p, ARHGAP5 (mouse): Y306‑p, ARHGAP5 iso3 (mouse): Y306‑p, ARHGAP5 (rat): Y305‑p Characterization Methods used to characterize site in vivo:  mutation of modification site, phospho-antibody, western blotting Relevant cell lines - cell types - tissues:  3T3-L1 (fibroblast), C2C12 (myoblast), MEF (fibroblast) Cellular systems studied:  cell lines Species studied:  mouse Enzymes shown to modify site in vitro:  Type Enzyme KINASE INSR (human) Upstream Regulation Treatments, proteins and their effect on site modification:  Treatments Referenced Treatments Manipulated Protein Referenced Protein Effect Notes IGF-1 increase Downstream Regulation Effect of modification (function):  intracellular localization Effect of modification (process):  cell differentiation, altered