Nathanson NM (2012) Regulation of neurokine receptor signaling and trafficking. Neurochem Int 61, 874-8 22306348

This page summarizes selected information from the record referenced above and curated into PhosphoSitePlus®, a comprehensive online resource for the study of protein post-translational modifications (NAR, 2015, 43:D512-20). To learn more about the scope of PhosphoSitePlus®, click here.

Click on the protein name to open the protein page, and on the RSD number to open the site page.

Download

S782-p - gp130 (human) ▲

Modsite: QVFSRsEsTQPLLDS SwissProt Entrez-Gene Orthologous residues gp130 (human): S782‑p, gp130 iso2 (human): ‑, gp130 iso3 (human): S721‑p, gp130 (mouse): S780‑p, gp130 (rat): S781‑p Characterization Methods used to characterize site in vivo:  mass spectrometry Relevant cell lines - cell types - tissues:  3T3-L1 (fibroblast) Cellular systems studied:  cell lines Species studied:  mouse Enzymes shown to modify site in vitro:  Type Enzyme KINASE CAMK2A (human) Upstream Regulation Treatments, proteins and their effect on site modification:  Treatments Referenced Treatments Manipulated Protein Referenced Protein Effect Notes CAMK2A (human) increase CAMK4 (human) increase Downstream Regulation Effect of modification (function):  receptor internalization, induced Effect of modification (process):  signaling pathway regulation, transcription, inhibited

S1044-p - LIFR (human) ▲

Modsite: WNLVsPDsPRsIDSN SwissProt Entrez-Gene Orthologous residues LIFR (human): S1044‑p, LIFR (mouse): S1039‑p, LIFR (rat): S1040‑p Characterization Methods used to characterize site in vivo:  mutation of modification site Disease tissue studied:  neuroblastoma Relevant cell lines - cell types - tissues:  NBFL Cellular systems studied:  cell lines Species studied:  human Upstream Regulation Treatments, proteins and their effect on site modification:  Treatments Referenced Treatments Manipulated Protein Referenced Protein Effect Notes ERK1 (human) increase ERK2 (human) increase Downstream Regulation Effect of modification (process):  transcription, inhibited