Curated Information
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Home > Curated Information Page > PubMed Id: 10572014
Kalo MS, Pasquale EB (1999) Multiple in vivo tyrosine phosphorylation sites in EphB receptors. Biochemistry 38, 14396-408 10572014
This page summarizes selected information from the record referenced above and curated into PhosphoSitePlus®, a comprehensive online resource for the study of protein post-translational modifications (NAR, 2015, 43:D512-20). To learn more about the scope of PhosphoSitePlus®, click here.
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Y579-p - EphB2 (chicken)
Modsite: FERADSEyTDKLQHy SwissProt Entrez-Gene
Orthologous residues
EphB2 (human): Y577‑p, EphB2 iso2 (human): Y577‑p, EphB2 iso3 (human): Y578‑p, EphB2 (mouse): Y577‑p, EphB2 iso4 (mouse): Y578‑p, EphB2 (rat): Y690‑p, EphB2 (chicken): Y579‑p
Characterization
Methods used to characterize site in vivo 2D analysis, mass spectrometry, phospho-antibody, phosphopeptide mapping
Relevant cell lines - cell types - tissues:  HEK293T (epithelial)
Cellular systems studied:  cell lines
Species studied:  human

Y586-p - EphB2 (chicken)
Modsite: yTDKLQHyTSGHSTY SwissProt Entrez-Gene
Orthologous residues
EphB2 (human): Y584‑p, EphB2 iso2 (human): Y584‑p, EphB2 iso3 (human): Y585‑p, EphB2 (mouse): Y584‑p, EphB2 iso4 (mouse): Y585‑p, EphB2 (rat): Y697‑p, EphB2 (chicken): Y586‑p
Characterization
Methods used to characterize site in vivo 2D analysis, mass spectrometry, phospho-antibody, phosphopeptide mapping
Relevant cell lines - cell types - tissues:  HEK293T (epithelial)
Cellular systems studied:  cell lines
Species studied:  human

Y614-p - EphB2 (chicken)
Modsite: MTPGMKIyIDPFTyE SwissProt Entrez-Gene
Orthologous residues
EphB2 (human): Y596‑p, EphB2 iso2 (human): Y596‑p, EphB2 iso3 (human): Y597‑p, EphB2 (mouse): Y596‑p, EphB2 iso4 (mouse): Y597‑p, EphB2 (rat): Y709‑p, EphB2 (chicken): Y614‑p
Characterization
Methods used to characterize site in vivo 2D analysis, mass spectrometry, phospho-antibody, phosphopeptide mapping
Relevant cell lines - cell types - tissues:  HEK293T (epithelial)
Cellular systems studied:  cell lines
Species studied:  human

Y620-p - EphB2 (chicken)
Modsite: IyIDPFTyEDPNEAV SwissProt Entrez-Gene
Orthologous residues
EphB2 (human): Y602‑p, EphB2 iso2 (human): Y602‑p, EphB2 iso3 (human): Y603‑p, EphB2 (mouse): Y602‑p, EphB2 iso4 (mouse): Y603‑p, EphB2 (rat): Y715‑p, EphB2 (chicken): Y620‑p
Characterization
Methods used to characterize site in vivo 2D analysis, mass spectrometry, phospho-antibody, phosphopeptide mapping
Relevant cell lines - cell types - tissues:  HEK293T (epithelial)
Cellular systems studied:  cell lines
Species studied:  human

Y677-p - EphB2 (chicken)
Modsite: IKTLKSGyTEKQRRD SwissProt Entrez-Gene
Orthologous residues
EphB2 (human): Y659‑p, EphB2 iso2 (human): Y659‑p, EphB2 iso3 (human): Y660‑p, EphB2 (mouse): Y659‑p, EphB2 iso4 (mouse): Y660‑p, EphB2 (rat): Y772‑p, EphB2 (chicken): Y677‑p
Characterization
Methods used to characterize site in vivo 2D analysis, mass spectrometry, phospho-antibody, phosphopeptide mapping
Relevant cell lines - cell types - tissues:  HEK293T (epithelial)
Cellular systems studied:  cell lines
Species studied:  human

Y754-p - EphB2 (chicken)
Modsite: GIAAGMKyLADMNyV SwissProt Entrez-Gene
Orthologous residues
EphB2 (human): Y736‑p, EphB2 iso2 (human): Y736‑p, EphB2 iso3 (human): Y737‑p, EphB2 (mouse): Y736‑p, EphB2 iso4 (mouse): Y737‑p, EphB2 (rat): Y849‑p, EphB2 (chicken): Y754‑p
Characterization
Methods used to characterize site in vivo 2D analysis, mass spectrometry, phospho-antibody, phosphopeptide mapping
Relevant cell lines - cell types - tissues:  HEK293T (epithelial)
Cellular systems studied:  cell lines
Species studied:  human

Y760-p - EphB2 (chicken)
Modsite: KyLADMNyVHRDLAA SwissProt Entrez-Gene
Orthologous residues
EphB2 (human): Y742‑p, EphB2 iso2 (human): Y742‑p, EphB2 iso3 (human): Y743‑p, EphB2 (mouse): Y742‑p, EphB2 iso4 (mouse): Y743‑p, EphB2 (rat): Y855‑p, EphB2 (chicken): Y760‑p
Characterization
Methods used to characterize site in vivo 2D analysis, mass spectrometry, phospho-antibody, phosphopeptide mapping
Relevant cell lines - cell types - tissues:  HEK293T (epithelial)
Cellular systems studied:  cell lines
Species studied:  human

Y798-p - EphB2 (chicken)
Modsite: DDTSDPTyTSALGGK SwissProt Entrez-Gene
Orthologous residues
EphB2 (human): Y780‑p, EphB2 iso2 (human): Y780‑p, EphB2 iso3 (human): Y781‑p, EphB2 (mouse): Y780‑p, EphB2 iso4 (mouse): Y781‑p, EphB2 (rat): Y893‑p, EphB2 (chicken): Y798‑p
Characterization
Methods used to characterize site in vivo 2D analysis, mass spectrometry, phospho-antibody, phosphopeptide mapping
Relevant cell lines - cell types - tissues:  HEK293T (epithelial)
Cellular systems studied:  cell lines
Species studied:  human

Y818-p - EphB2 (chicken)
Modsite: TAPEAIQyRKFTSAS SwissProt Entrez-Gene
Orthologous residues
EphB2 (human): Y800‑p, EphB2 iso2 (human): Y800‑p, EphB2 iso3 (human): Y801‑p, EphB2 (mouse): Y800‑p, EphB2 iso4 (mouse): Y801‑p, EphB2 (rat): Y913‑p, EphB2 (chicken): Y818‑p
Characterization
Methods used to characterize site in vivo 2D analysis, mass spectrometry, phospho-antibody, phosphopeptide mapping
Relevant cell lines - cell types - tissues:  HEK293T (epithelial)
Cellular systems studied:  cell lines
Species studied:  human

Y830-p - EphB2 (chicken)
Modsite: SASDVWSyGIVMWEV SwissProt Entrez-Gene
Orthologous residues
EphB2 (human): Y812‑p, EphB2 iso2 (human): Y812‑p, EphB2 iso3 (human): Y813‑p, EphB2 (mouse): Y812‑p, EphB2 iso4 (mouse): Y813‑p, EphB2 (rat): Y925‑p, EphB2 (chicken): Y830‑p
Characterization
Methods used to characterize site in vivo 2D analysis, mass spectrometry, phospho-antibody, phosphopeptide mapping
Relevant cell lines - cell types - tissues:  HEK293T (epithelial)
Cellular systems studied:  cell lines
Species studied:  human

Y948-p - EphB2 (chicken)
Modsite: DAIKMSQyKESFASA SwissProt Entrez-Gene
Orthologous residues
EphB2 (human): Y930‑p, EphB2 iso2 (human): Y930‑p, EphB2 iso3 (human): Y931‑p, EphB2 (mouse): Y930‑p, EphB2 iso4 (mouse): Y931‑p, EphB2 (rat): Y1043‑p, EphB2 (chicken): Y948‑p
Characterization
Methods used to characterize site in vivo 2D analysis, mass spectrometry, phospho-antibody, phosphopeptide mapping
Relevant cell lines - cell types - tissues:  HEK293T (epithelial)
Cellular systems studied:  cell lines
Species studied:  human

Y594-p - EphB6 (chicken)
Modsite: SKRRETPyTDRLQQy SwissProt Entrez-Gene
Orthologous residues
EphB6 (human): Y628‑p, EphB6 (mouse): Y621‑p, EphB6 (rat): Y620‑p, EphB6 (chicken): Y594‑p
Characterization
Methods used to characterize site in vivo 2D analysis, mass spectrometry, phospho-antibody, phosphopeptide mapping
Relevant cell lines - cell types - tissues:  HEK293T (epithelial)
Cellular systems studied:  cell lines
Species studied:  human
Enzymes shown to modify site in vitro
Type Enzyme
KINASE EphB6 (chicken)

Y601-p - EphB6 (chicken)
Modsite: yTDRLQQyISTRGLG SwissProt Entrez-Gene
Orthologous residues
EphB6 (human): Y635‑p, EphB6 (mouse): Y628‑p, EphB6 (rat): Y627‑p, EphB6 (chicken): Y601‑p
Characterization
Methods used to characterize site in vivo 2D analysis, mass spectrometry, phospho-antibody, phosphopeptide mapping
Relevant cell lines - cell types - tissues:  HEK293T (epithelial)
Cellular systems studied:  cell lines
Species studied:  human
Enzymes shown to modify site in vitro
Type Enzyme
KINASE EphB6 (chicken)

Y611-p - EphB6 (chicken)
Modsite: TRGLGVKyyIDPSTy SwissProt Entrez-Gene
Orthologous residues
EphB6 (human): Y644‑p, EphB6 (mouse): Y637‑p, EphB6 (rat): Y636‑p, EphB6 (chicken): Y611‑p
Characterization
Methods used to characterize site in vivo 2D analysis, mass spectrometry, phospho-antibody, phosphopeptide mapping
Relevant cell lines - cell types - tissues:  HEK293T (epithelial)
Cellular systems studied:  cell lines
Species studied:  human
Enzymes shown to modify site in vitro
Type Enzyme
KINASE EphB6 (chicken)

Y612-p - EphB6 (chicken)
Modsite: RGLGVKyyIDPSTyE SwissProt Entrez-Gene
Orthologous residues
EphB6 (human): Y645‑p, EphB6 (mouse): Y638‑p, EphB6 (rat): Y637‑p, EphB6 (chicken): Y612‑p
Characterization
Methods used to characterize site in vivo 2D analysis, mass spectrometry, phospho-antibody, phosphopeptide mapping
Relevant cell lines - cell types - tissues:  HEK293T (epithelial)
Cellular systems studied:  cell lines
Species studied:  human
Enzymes shown to modify site in vitro
Type Enzyme
KINASE EphB6 (chicken)

Y618-p - EphB6 (chicken)
Modsite: yyIDPSTyEDPNEAI SwissProt Entrez-Gene
Orthologous residues
EphB6 (human): Y651‑p, EphB6 (mouse): Y644‑p, EphB6 (rat): Y643‑p, EphB6 (chicken): Y618‑p
Characterization
Methods used to characterize site in vivo 2D analysis, mass spectrometry, phospho-antibody, phosphopeptide mapping
Relevant cell lines - cell types - tissues:  HEK293T (epithelial)
Cellular systems studied:  cell lines
Species studied:  human
Enzymes shown to modify site in vitro
Type Enzyme
KINASE EphB6 (chicken)

Y664-p - EphB6 (chicken)
Modsite: KHPGKREyTVAIKTL SwissProt Entrez-Gene
Orthologous residues
EphB6 (human): Q697‑p, EphB6 (mouse): Q690‑p, EphB6 (rat): Q689‑p, EphB6 (chicken): Y664‑p
Characterization
Methods used to characterize site in vivo 2D analysis, mass spectrometry, phospho-antibody, phosphopeptide mapping
Relevant cell lines - cell types - tissues:  HEK293T (epithelial)
Cellular systems studied:  cell lines
Species studied:  human

Y675-p - EphB6 (chicken)
Modsite: IKTLKSGyTDEQRRE SwissProt Entrez-Gene
Orthologous residues
EphB6 (human): G708‑p, EphB6 (mouse): G701‑p, EphB6 (rat): G700‑p, EphB6 (chicken): Y675‑p
Characterization
Methods used to characterize site in vivo 2D analysis, mass spectrometry, phospho-antibody, phosphopeptide mapping
Relevant cell lines - cell types - tissues:  HEK293T (epithelial)
Cellular systems studied:  cell lines
Species studied:  human

Y752-p - EphB6 (chicken)
Modsite: GIAAGMRyLSDMNyV SwissProt Entrez-Gene
Orthologous residues
EphB6 (human): Y785‑p, EphB6 (mouse): Y778‑p, EphB6 (rat): Y777‑p, EphB6 (chicken): Y752‑p
Characterization
Methods used to characterize site in vivo 2D analysis, mass spectrometry, phospho-antibody, phosphopeptide mapping
Relevant cell lines - cell types - tissues:  HEK293T (epithelial)
Cellular systems studied:  cell lines
Species studied:  human

Y758-p - EphB6 (chicken)
Modsite: RyLSDMNyVHRDLAA SwissProt Entrez-Gene
Orthologous residues
EphB6 (human): F791‑p, EphB6 (mouse): F784‑p, EphB6 (rat): F783‑p, EphB6 (chicken): Y758‑p
Characterization
Methods used to characterize site in vivo 2D analysis, mass spectrometry, phospho-antibody, phosphopeptide mapping
Relevant cell lines - cell types - tissues:  HEK293T (epithelial)
Cellular systems studied:  cell lines
Species studied:  human

Y796-p - EphB6 (chicken)
Modsite: DDASNPTyTGALGCK SwissProt Entrez-Gene
Orthologous residues
EphB6 (human): G820‑p, EphB6 (mouse): G813‑p, EphB6 (rat): G812‑p, EphB6 (chicken): Y796‑p
Characterization
Methods used to characterize site in vivo 2D analysis, mass spectrometry, phospho-antibody, phosphopeptide mapping
Relevant cell lines - cell types - tissues:  HEK293T (epithelial)
Cellular systems studied:  cell lines
Species studied:  human
Enzymes shown to modify site in vitro
Type Enzyme
KINASE EphB6 (chicken)

Y816-p - EphB6 (chicken)
Modsite: TAPEAVQyRKFTSSS SwissProt Entrez-Gene
Orthologous residues
EphB6 (human): H835‑p, EphB6 (mouse): H828‑p, EphB6 (rat): H827‑p, EphB6 (chicken): Y816‑p
Characterization
Methods used to characterize site in vivo 2D analysis, mass spectrometry, phospho-antibody, phosphopeptide mapping
Relevant cell lines - cell types - tissues:  HEK293T (epithelial)
Cellular systems studied:  cell lines
Species studied:  human

Y946-p - EphB6 (chicken)
Modsite: DAIKMGRyKENFDQA SwissProt Entrez-Gene
Orthologous residues
EphB6 (human): Y965‑p, EphB6 (mouse): Y958‑p, EphB6 (rat): Y957‑p, EphB6 (chicken): Y946‑p
Characterization
Methods used to characterize site in vivo 2D analysis, mass spectrometry, phospho-antibody, phosphopeptide mapping
Relevant cell lines - cell types - tissues:  HEK293T (epithelial)
Cellular systems studied:  cell lines
Species studied:  human