Forcales SV, et al. (2012) Signal-dependent incorporation of MyoD-BAF60c into Brg1-based SWI/SNF chromatin-remodelling complex. EMBO J 31, 301-16 22068056

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T229-p - SMARCD3 (mouse) ▲

Modsite: HLVEWHRtPTTQETD SwissProt Entrez-Gene Orthologous residues SMARCD3 (human): T229‑p, SMARCD3 (mouse): T229‑p, SMARCD3 (rat): T216‑p Characterization Methods used to characterize site in vivo:  [32P] ATP in vitro, immunoassay, immunoprecipitation, mutation of modification site, phospho-antibody, western blotting Relevant cell lines - cell types - tissues:  C2C12 (myoblast) Cellular systems studied:  cell lines Species studied:  mouse Enzymes shown to modify site in vitro:  Type Enzyme KINASE P38A (mouse) KINASE P38B (mouse) Upstream Regulation Potential in vivo enzymes for site:  Type Enzyme Evidence Notes KINASE P38B (human) activation of upstream enzyme, pharmacological inhibitor of upstream enzyme, modification site within consensus motif KINASE P38A (human) activation of upstream enzyme, pharmacological inhibitor of upstream enzyme, modification site within consensus motif Treatments, proteins and their effect on site modification:  Treatments Referenced Treatments Manipulated Protein Referenced Protein Effect Notes SB203580 decrease MKK6 (mouse) increase Downstream Regulation Effect of modification (function):  molecular association, regulation Effect of modification (process):  cell differentiation, induced, chromatin organization, altered, transcription, induced Modification regulates interactions with:  Interacting molecule Interacting domains Effect Consequences (function) Consequences (process) Detection assays SMARCA4 (mouse) Induces pull-down assay, co-immunoprecipitation