Curated Information
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Home > Curated Information Page > Cst Curation Set #6046
Tucker M (2009) CST Curation Set: 6046; Year: 2009; Biosample/Treatment: tissue, skin/untreated; Disease: melanoma skin cancer; SILAC: -; Specificities of Antibodies Used to Purify Peptides prior to LCMS: RXXp[ST] Antibodies Used to Purify Peptides prior to LCMS: Phospho-Akt Substrate (RXRXXS*/T*) (23C8D2) Rabbit mAb Cat#: 10001, PTMScan(R) Phospho-Akt Substrate Motif (RXRXXS*/T*) Immunoaffinity Beads Cat#: 1979
This page summarizes selected information from the record referenced above and curated into PhosphoSitePlus®, a comprehensive online resource for the study of protein post-translational modifications (NAR, 2015, 43:D512-20). To learn more about the scope of PhosphoSitePlus®, click here.
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S5642-p - AHNAK2 (human)
Modsite: DKPESKKsGLLWFWL SwissProt Entrez-Gene
Orthologous residues
AHNAK2 (human): S5642‑p, AHNAK2 iso2 (human): S640‑p, AHNAK2 iso3 (human): S5542‑p, AHNAK2 (mouse): , AHNAK2 iso2 (mouse): A623‑p, AHNAK2 (rat): S6885‑p
Characterization
Methods used to characterize site in vivo mass spectrometry
Disease tissue studied:  melanoma skin cancer
Relevant cell lines - cell types - tissues:  skin
Cellular systems studied:  tissue
Species studied:  human

S272-p - amphiphysin (human)
Modsite: EEPsPLPsPTAsPNH SwissProt Entrez-Gene
Orthologous residues
amphiphysin (human): S272‑p, amphiphysin (mouse): S272‑p, amphiphysin (rat): S272‑p
Characterization
Methods used to characterize site in vivo mass spectrometry
Disease tissue studied:  melanoma skin cancer
Relevant cell lines - cell types - tissues:  skin
Cellular systems studied:  tissue
Species studied:  human

S293-p - amphiphysin (human)
Modsite: PAPARPRsPsQTRKG SwissProt Entrez-Gene
Orthologous residues
amphiphysin (human): S293‑p, amphiphysin (mouse): S293‑p, amphiphysin (rat): S293‑p
Characterization
Methods used to characterize site in vivo mass spectrometry
Disease tissue studied:  melanoma skin cancer
Relevant cell lines - cell types - tissues:  skin
Cellular systems studied:  tissue
Species studied:  human

Y15-p - CDK1 (human)
Modsite: EkIGEGtyGVVykGR SwissProt Entrez-Gene
Orthologous residues
CDK1 (human): Y15‑p, CDK1 iso2 (human): Y15‑p, CDK1 (mouse): Y15‑p, CDK1 (rat): Y15‑p, CDK1 (chicken): Y15‑p, CDK1 (fruit fly): Y15‑p
Characterization
Methods used to characterize site in vivo mass spectrometry
Disease tissue studied:  melanoma skin cancer
Relevant cell lines - cell types - tissues:  skin
Cellular systems studied:  tissue
Species studied:  human

Y15-p - CDK2 (human)
Modsite: EkIGEGtyGVVykAR SwissProt Entrez-Gene
Orthologous residues
CDK2 (human): Y15‑p, CDK2 iso2 (human): Y15‑p, CDK2 (mouse): Y15‑p, CDK2 (rat): Y15‑p
Characterization
Methods used to characterize site in vivo mass spectrometry
Disease tissue studied:  melanoma skin cancer
Relevant cell lines - cell types - tissues:  skin
Cellular systems studied:  tissue
Species studied:  human

Y15-p - CDK3 (human)
Modsite: EkIGEGtyGVVyKAK SwissProt Entrez-Gene
Orthologous residues
CDK3 (human): Y15‑p, CDK3 (mouse): Y15‑p, CDK3 (cow): Y15‑p
Characterization
Methods used to characterize site in vivo mass spectrometry
Disease tissue studied:  melanoma skin cancer
Relevant cell lines - cell types - tissues:  skin
Cellular systems studied:  tissue
Species studied:  human

Y279-p - GSK3A (human)
Modsite: RGEPNVsyICsRyyR SwissProt Entrez-Gene
Orthologous residues
GSK3A (human): Y279‑p, GSK3A (mouse): Y279‑p, GSK3A (rat): Y279‑p, GSK3A (cow): Y279‑p
Characterization
Methods used to characterize site in vivo mass spectrometry
Disease tissue studied:  melanoma skin cancer
Relevant cell lines - cell types - tissues:  skin
Cellular systems studied:  tissue
Species studied:  human

Y216-p - GSK3B (human)
Modsite: RGEPNVsyICsRyyR SwissProt Entrez-Gene
Orthologous residues
GSK3B (human): Y216‑p, GSK3B iso2 (human): Y216‑p, GSK3B (mouse): Y216‑p, GSK3B (rat): Y216‑p, GSK3B (rabbit): Y216‑p
Characterization
Methods used to characterize site in vivo mass spectrometry
Disease tissue studied:  melanoma skin cancer
Relevant cell lines - cell types - tissues:  skin
Cellular systems studied:  tissue
Species studied:  human

T257-p - LARP7 (human)
Modsite: KMKRsRPtsEGsDIE SwissProt Entrez-Gene
Orthologous residues
LARP7 (human): T257‑p, LARP7 iso2 (human): , LARP7 iso3 (human): T264‑p, LARP7 (mouse): A252‑p, LARP7 (rat): A253‑p
Characterization
Methods used to characterize site in vivo mass spectrometry
Disease tissue studied:  melanoma skin cancer
Relevant cell lines - cell types - tissues:  skin
Cellular systems studied:  tissue
Species studied:  human

S258-p - LARP7 (human)
Modsite: MKRsRPtsEGsDIEs SwissProt Entrez-Gene
Orthologous residues
LARP7 (human): S258‑p, LARP7 iso2 (human): , LARP7 iso3 (human): S265‑p, LARP7 (mouse): S253‑p, LARP7 (rat): S254‑p
Characterization
Methods used to characterize site in vivo mass spectrometry
Disease tissue studied:  melanoma skin cancer
Relevant cell lines - cell types - tissues:  skin
Cellular systems studied:  tissue
Species studied:  human

S261-p - LARP7 (human)
Modsite: sRPtsEGsDIEstEP SwissProt Entrez-Gene
Orthologous residues
LARP7 (human): S261‑p, LARP7 iso2 (human): , LARP7 iso3 (human): S268‑p, LARP7 (mouse): S256‑p, LARP7 (rat): S257‑p
Characterization
Methods used to characterize site in vivo mass spectrometry
Disease tissue studied:  melanoma skin cancer
Relevant cell lines - cell types - tissues:  skin
Cellular systems studied:  tissue
Species studied:  human

S802-p - MYPT1 (human)
Modsite: sQLNRPNsLVGITSA SwissProt Entrez-Gene
Orthologous residues
MYPT1 (human): S802‑p, MYPT1 iso2 (human): S802‑p, MYPT1 iso3 (human): S746‑p, MYPT1 iso4 (human): S743‑p, MYPT1 (mouse): S801‑p, MYPT1 (rat): S804‑p, MYPT1 (pig): S802‑p, MYPT1 (chicken): S800‑p, MYPT1 (cow): S800‑p
Characterization
Methods used to characterize site in vivo mass spectrometry
Disease tissue studied:  melanoma skin cancer
Relevant cell lines - cell types - tissues:  skin
Cellular systems studied:  tissue
Species studied:  human

S271-p - NEURL1B (human)
Modsite: RERPRPAssPALLEA SwissProt Entrez-Gene
Orthologous residues
NEURL1B (human): S271‑p, NEURL1B iso2 (human): S89‑p, NEURL1B iso3 (human): , NEURL1B (mouse): S262‑p
Characterization
Methods used to characterize site in vivo mass spectrometry
Disease tissue studied:  melanoma skin cancer
Relevant cell lines - cell types - tissues:  skin
Cellular systems studied:  tissue
Species studied:  human

Y182-p - P38A (human)
Modsite: tDDEMtGyVAtRWYR SwissProt Entrez-Gene
Orthologous residues
P38A (human): Y182‑p, P38A iso2 (human): Y182‑p, P38A (mouse): Y182‑p, P38A iso3 (mouse): Y182‑p, P38A (rat): Y182‑p, P38A (salmonid): Y183‑p
Characterization
Methods used to characterize site in vivo mass spectrometry
Disease tissue studied:  melanoma skin cancer
Relevant cell lines - cell types - tissues:  skin
Cellular systems studied:  tissue
Species studied:  human

Y849-p - PRP4 (human)
Modsite: ADNDItPyLVsRFyR SwissProt Entrez-Gene
Orthologous residues
PRP4 (human): Y849‑p, PRP4 (mouse): Y849‑p, PRP4 (rat): Y849‑p
Characterization
Methods used to characterize site in vivo mass spectrometry
Disease tissue studied:  melanoma skin cancer
Relevant cell lines - cell types - tissues:  skin
Cellular systems studied:  tissue
Species studied:  human

T112-p - Pumilio-1 (human)
Modsite: NskHRWPtGDNIHAE SwissProt Entrez-Gene
Orthologous residues
Pumilio‑1 (human): T112‑p, Pumilio‑1 iso2 (human): T112‑p, Pumilio‑1 iso3 (human): T112‑p, Pumilio‑1 iso4 (human): T148‑p, Pumilio‑1 (mouse): T112‑p, Pumilio‑1 (rat): T112‑p
Characterization
Methods used to characterize site in vivo mass spectrometry
Disease tissue studied:  melanoma skin cancer
Relevant cell lines - cell types - tissues:  skin
Cellular systems studied:  tissue
Species studied:  human

S754-p - SCYL1 (human)
Modsite: sTQPRPDsWGEDNWE SwissProt Entrez-Gene
Orthologous residues
SCYL1 (human): S754‑p, SCYL1 iso2 (human): S737‑p, SCYL1 (mouse): S752‑p, SCYL1 (rat): S753‑p
Characterization
Methods used to characterize site in vivo mass spectrometry
Disease tissue studied:  melanoma skin cancer
Relevant cell lines - cell types - tissues:  skin
Cellular systems studied:  tissue
Species studied:  human

S297-p - SPRED2 (human)
Modsite: TQPSRGKsRRRKEDG SwissProt Entrez-Gene
Orthologous residues
SPRED2 (human): S297‑p, SPRED2 iso2 (human): S294‑p, SPRED2 (mouse): S289‑p, SPRED2 (rat): S289‑p
Characterization
Methods used to characterize site in vivo mass spectrometry
Disease tissue studied:  melanoma skin cancer
Relevant cell lines - cell types - tissues:  skin
Cellular systems studied:  tissue
Species studied:  human

S297-p - SRm300 (human)
Modsite: ALAGRsPsPAsGRRG SwissProt Entrez-Gene
Orthologous residues
SRm300 (human): S297‑p, SRm300 iso2 (human): S297‑p, SRm300 (mouse): P297‑p, SRm300 iso2 (mouse): P201‑p, SRm300 iso3 (mouse): P297‑p, SRm300 (rat): P297‑p, SRm300 (cow): S297‑p
Characterization
Methods used to characterize site in vivo mass spectrometry
Disease tissue studied:  melanoma skin cancer
Relevant cell lines - cell types - tissues:  skin
Cellular systems studied:  tissue
Species studied:  human

T1080-p - VIRMA (human)
Modsite: QGVNEKLtISEETLA SwissProt Entrez-Gene
Orthologous residues
VIRMA (human): T1080‑p, VIRMA (mouse): T1079‑p, VIRMA (rat): T1130‑p
Characterization
Methods used to characterize site in vivo mass spectrometry
Disease tissue studied:  melanoma skin cancer
Relevant cell lines - cell types - tissues:  skin
Cellular systems studied:  tissue
Species studied:  human