Curated Information
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Home > Curated Information Page > Cst Curation Set #5530
Rikova K (2008) CST Curation Set: 5530; Year: 2008; Biosample/Treatment: tissue, lung/untreated; Disease: non-small cell lung cancer; SILAC: -; Specificities of Antibodies Used to Purify Peptides prior to LCMS: pY Antibodies Used to Purify Peptides prior to LCMS: Phospho-Tyrosine Mouse mAb (P-Tyr-100) Cat#: 9411, PTMScan(R) Phospho-Tyr Motif (Y*) Immunoaffinity Beads Cat#: 1991
This page summarizes selected information from the record referenced above and curated into PhosphoSitePlus®, a comprehensive online resource for the study of protein post-translational modifications (NAR, 2015, 43:D512-20). To learn more about the scope of PhosphoSitePlus®, click here.
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Y24-p - ANXA2 (human)
Modsite: HstPPsAyGsVkAyt SwissProt Entrez-Gene
Orthologous residues
ANXA2 (human): Y24‑p, ANXA2 iso2 (human): Y42‑p, ANXA2 (mouse): Y24‑p, ANXA2 (rat): Y24‑p, ANXA2 (dog): Y24‑p, ANXA2 (cow): Y24‑p
Characterization
Methods used to characterize site in vivo mass spectrometry
Disease tissue studied:  lung cancer, non-small cell lung cancer
Relevant cell lines - cell types - tissues:  lung
Cellular systems studied:  tissue
Species studied:  human

Y85-p - CARKD (human)
Modsite: VVGGCQEytGAPYFA SwissProt Entrez-Gene
Orthologous residues
CARKD (human): Y85‑p, CARKD iso2 (human): Y85‑p, CARKD (mouse): Y81‑p, CARKD (rat): Y65‑p
Characterization
Methods used to characterize site in vivo mass spectrometry
Disease tissue studied:  lung cancer, non-small cell lung cancer
Relevant cell lines - cell types - tissues:  lung
Cellular systems studied:  tissue
Species studied:  human

S173-p - CCDC132 (human)
Modsite: LLIGLLKsLRTIkTL SwissProt Entrez-Gene
Orthologous residues
CCDC132 (human): S173‑p, CCDC132 iso3 (human): S143‑p, CCDC132 (mouse): S173‑p, CCDC132 (rat):
Characterization
Methods used to characterize site in vivo mass spectrometry
Disease tissue studied:  lung cancer, non-small cell lung cancer
Relevant cell lines - cell types - tissues:  lung
Cellular systems studied:  tissue
Species studied:  human

Y221-p - CRK (human)
Modsite: GGPEPGPyAQPsVNt SwissProt Entrez-Gene
Orthologous residues
CRK (human): Y221‑p, CRK iso2 (human): , CRK (mouse): Y221‑p, CRK iso3 (mouse): , CRK (rat): Y221‑p, CRK (chicken): Y222‑p
Characterization
Methods used to characterize site in vivo mass spectrometry
Disease tissue studied:  lung cancer, non-small cell lung cancer
Relevant cell lines - cell types - tissues:  lung
Cellular systems studied:  tissue
Species studied:  human

Y207-p - CRKL (human)
Modsite: IPEPAHAyAQPQttt SwissProt Entrez-Gene
Orthologous residues
CRKL (human): Y207‑p, CRKL (mouse): Y207‑p, CRKL (rat): Y207‑p
Characterization
Methods used to characterize site in vivo mass spectrometry
Disease tissue studied:  lung cancer, non-small cell lung cancer
Relevant cell lines - cell types - tissues:  lung
Cellular systems studied:  tissue
Species studied:  human

S1122-p - DNAJC13 (human)
Modsite: QLPRLYLsGVFFFIM SwissProt Entrez-Gene
Orthologous residues
DNAJC13 (human): S1122‑p, DNAJC13 (mouse): S1122‑p
Characterization
Methods used to characterize site in vivo mass spectrometry
Disease tissue studied:  lung cancer, non-small cell lung cancer
Relevant cell lines - cell types - tissues:  lung
Cellular systems studied:  tissue
Species studied:  human

Y321-p - DYRK1A (human)
Modsite: LGQRIyQyIQsRFYR SwissProt Entrez-Gene
Orthologous residues
DYRK1A (human): Y321‑p, DYRK1A iso2 (human): Y312‑p, DYRK1A iso4 (human): Y321‑p, DYRK1A (mouse): Y321‑p, DYRK1A (rat): Y321‑p, DYRK1A (rabbit):
Characterization
Methods used to characterize site in vivo mass spectrometry
Disease tissue studied:  lung cancer, non-small cell lung cancer
Relevant cell lines - cell types - tissues:  lung
Cellular systems studied:  tissue
Species studied:  human

Y273-p - DYRK1B (human)
Modsite: LGQRIyQyIQsRFYR SwissProt Entrez-Gene
Orthologous residues
DYRK1B (human): Y273‑p, DYRK1B iso2 (human): Y273‑p, DYRK1B (mouse): Y273‑p, DYRK1B (rat): Y273‑p
Characterization
Methods used to characterize site in vivo mass spectrometry
Disease tissue studied:  lung cancer, non-small cell lung cancer
Relevant cell lines - cell types - tissues:  lung
Cellular systems studied:  tissue
Species studied:  human

T202-p - ERK1 (human)
Modsite: HDHtGFLtEyVAtRW SwissProt Entrez-Gene
Orthologous residues
ERK1 (human): T202‑p, ERK1 iso2 (human): T202‑p, ERK1 iso3 (human): T202‑p, ERK1 (mouse): T203‑p, ERK1 (rat): T203‑p, ERK1 (hamster): T192‑p
Characterization
Methods used to characterize site in vivo mass spectrometry
Disease tissue studied:  lung cancer, non-small cell lung cancer
Relevant cell lines - cell types - tissues:  lung
Cellular systems studied:  tissue
Species studied:  human

Y204-p - ERK1 (human)
Modsite: HtGFLtEyVAtRWyr SwissProt Entrez-Gene
Orthologous residues
ERK1 (human): Y204‑p, ERK1 iso2 (human): Y204‑p, ERK1 iso3 (human): Y204‑p, ERK1 (mouse): Y205‑p, ERK1 (rat): Y205‑p, ERK1 (hamster): Y194‑p
Characterization
Methods used to characterize site in vivo mass spectrometry
Disease tissue studied:  lung cancer, non-small cell lung cancer
Relevant cell lines - cell types - tissues:  lung
Cellular systems studied:  tissue
Species studied:  human

T185-p - ERK2 (human)
Modsite: HDHtGFLtEyVAtRW SwissProt Entrez-Gene
Orthologous residues
ERK2 (human): T185‑p, ERK2 (mouse): T183‑p, ERK2 (rat): T183‑p, ERK2 (chicken): T193‑p, ERK2 (cow): T185‑p
Characterization
Methods used to characterize site in vivo mass spectrometry
Disease tissue studied:  lung cancer, non-small cell lung cancer
Relevant cell lines - cell types - tissues:  lung
Cellular systems studied:  tissue
Species studied:  human

Y187-p - ERK2 (human)
Modsite: HtGFLtEyVAtRWyr SwissProt Entrez-Gene
Orthologous residues
ERK2 (human): Y187‑p, ERK2 (mouse): Y185‑p, ERK2 (rat): Y185‑p, ERK2 (chicken): Y195‑p, ERK2 (cow): Y187‑p
Characterization
Methods used to characterize site in vivo mass spectrometry
Disease tissue studied:  lung cancer, non-small cell lung cancer
Relevant cell lines - cell types - tissues:  lung
Cellular systems studied:  tissue
Species studied:  human

Y576-p - FAK (human)
Modsite: RyMEDstyyKAsKGK SwissProt Entrez-Gene
Orthologous residues
FAK (human): Y576‑p, FAK iso2 (human): Y424‑p, FAK iso5 (human): Y576‑p, FAK (mouse): Y576‑p, FAK iso2 (mouse): Y607‑p, FAK iso4 (mouse): Y576‑p, FAK iso9 (mouse): , FAK (rat): Y576‑p, FAK (chicken): Y576‑p, FAK iso5 (chicken):
Characterization
Methods used to characterize site in vivo mass spectrometry
Disease tissue studied:  lung cancer, non-small cell lung cancer
Relevant cell lines - cell types - tissues:  lung
Cellular systems studied:  tissue
Species studied:  human

Y213-p - Fyn (human)
Modsite: RKLDNGGyyITtRAQ SwissProt Entrez-Gene
Orthologous residues
Fyn (human): Y213‑p, Fyn iso2 (human): Y213‑p, Fyn iso3 (human): Y213‑p, Fyn (mouse): Y213‑p, Fyn (rat): Y213‑p
Characterization
Methods used to characterize site in vivo mass spectrometry
Disease tissue studied:  lung cancer, non-small cell lung cancer
Relevant cell lines - cell types - tissues:  lung
Cellular systems studied:  tissue
Species studied:  human

Y1105-p - GRF-1 (human)
Modsite: RNEEENIysVPHDst SwissProt Entrez-Gene
Orthologous residues
GRF‑1 (human): Y1105‑p, GRF‑1 (mouse): Y1105‑p, GRF‑1 (rat): Y1105‑p
Characterization
Methods used to characterize site in vivo mass spectrometry
Disease tissue studied:  lung cancer, non-small cell lung cancer
Relevant cell lines - cell types - tissues:  lung
Cellular systems studied:  tissue
Species studied:  human

S762-p - GRIP1 (human)
Modsite: TDAQSASsPKKFPIS SwissProt Entrez-Gene
Orthologous residues
GRIP1 (human): S762‑p, GRIP1 iso2 (human): S762‑p, GRIP1 (mouse): S761‑p, GRIP1 iso2 (mouse): S683‑p, GRIP1 iso3 (mouse): S682‑p, GRIP1 (rat): S761‑p
Characterization
Methods used to characterize site in vivo mass spectrometry
Disease tissue studied:  lung cancer, non-small cell lung cancer
Relevant cell lines - cell types - tissues:  lung
Cellular systems studied:  tissue
Species studied:  human

S278-p - GSK3A (human)
Modsite: VRGEPNVsyICsRyy SwissProt Entrez-Gene
Orthologous residues
GSK3A (human): S278‑p, GSK3A (mouse): S278‑p, GSK3A (rat): S278‑p, GSK3A (cow): S278‑p
Characterization
Methods used to characterize site in vivo mass spectrometry
Disease tissue studied:  lung cancer, non-small cell lung cancer
Relevant cell lines - cell types - tissues:  lung
Cellular systems studied:  tissue
Species studied:  human

Y279-p - GSK3A (human)
Modsite: RGEPNVsyICsRyyR SwissProt Entrez-Gene
Orthologous residues
GSK3A (human): Y279‑p, GSK3A (mouse): Y279‑p, GSK3A (rat): Y279‑p, GSK3A (cow): Y279‑p
Characterization
Methods used to characterize site in vivo mass spectrometry
Disease tissue studied:  lung cancer, non-small cell lung cancer
Relevant cell lines - cell types - tissues:  lung
Cellular systems studied:  tissue
Species studied:  human

S215-p - GSK3B (human)
Modsite: VRGEPNVsyICsRyy SwissProt Entrez-Gene
Orthologous residues
GSK3B (human): S215‑p, GSK3B iso2 (human): S215‑p, GSK3B (mouse): S215‑p, GSK3B (rat): S215‑p, GSK3B (rabbit): S215‑p
Characterization
Methods used to characterize site in vivo mass spectrometry
Disease tissue studied:  lung cancer, non-small cell lung cancer
Relevant cell lines - cell types - tissues:  lung
Cellular systems studied:  tissue
Species studied:  human

Y216-p - GSK3B (human)
Modsite: RGEPNVsyICsRyyR SwissProt Entrez-Gene
Orthologous residues
GSK3B (human): Y216‑p, GSK3B iso2 (human): Y216‑p, GSK3B (mouse): Y216‑p, GSK3B (rat): Y216‑p, GSK3B (rabbit): Y216‑p
Characterization
Methods used to characterize site in vivo mass spectrometry
Disease tissue studied:  lung cancer, non-small cell lung cancer
Relevant cell lines - cell types - tissues:  lung
Cellular systems studied:  tissue
Species studied:  human

Y25-p - HBA1 (human)
Modsite: VGAHAGEyGAEALER SwissProt Entrez-Gene
Orthologous residues
HBA1 (human): Y25‑p, HBA1 (mouse): Y25‑p, HBA1 (rat): Y25‑p
Characterization
Methods used to characterize site in vivo mass spectrometry
Disease tissue studied:  lung cancer, non-small cell lung cancer
Relevant cell lines - cell types - tissues:  lung
Cellular systems studied:  tissue
Species studied:  human

Y352-p - HIPK1 (human)
Modsite: SkAVCstyLQsRYYR SwissProt Entrez-Gene
Orthologous residues
HIPK1 (human): Y352‑p, HIPK1 iso2 (human): Y352‑p, HIPK1 iso4 (human): , HIPK1 (mouse): Y352‑p, HIPK1 (rat): Y352‑p
Characterization
Methods used to characterize site in vivo mass spectrometry
Disease tissue studied:  lung cancer, non-small cell lung cancer
Relevant cell lines - cell types - tissues:  lung
Cellular systems studied:  tissue
Species studied:  human

Y361-p - HIPK2 (human)
Modsite: SkAVCstyLQsRYyR SwissProt Entrez-Gene
Orthologous residues
HIPK2 (human): Y361‑p, HIPK2 (mouse): Y361‑p, HIPK2 (rat): Y361‑p
Characterization
Methods used to characterize site in vivo mass spectrometry
Disease tissue studied:  lung cancer, non-small cell lung cancer
Relevant cell lines - cell types - tissues:  lung
Cellular systems studied:  tissue
Species studied:  human

Y359-p - HIPK3 (human)
Modsite: SkTVCstyLQsRYYR SwissProt Entrez-Gene
Orthologous residues
HIPK3 (human): Y359‑p, HIPK3 iso2 (human): Y359‑p, HIPK3 (mouse): Y359‑p, HIPK3 (rat): Y359‑p
Characterization
Methods used to characterize site in vivo mass spectrometry
Disease tissue studied:  lung cancer, non-small cell lung cancer
Relevant cell lines - cell types - tissues:  lung
Cellular systems studied:  tissue
Species studied:  human

Y185-p - JNK2 (human)
Modsite: tNFMMtPyVVtRYYR SwissProt Entrez-Gene
Orthologous residues
JNK2 (human): Y185‑p, JNK2 iso2 (human): Y185‑p, JNK2 iso3 (human): Y185‑p, JNK2 (mouse): Y185‑p, JNK2 iso4 (mouse): Y185‑p, JNK2 (rat): Y185‑p
Characterization
Methods used to characterize site in vivo mass spectrometry
Disease tissue studied:  lung cancer, non-small cell lung cancer
Relevant cell lines - cell types - tissues:  lung
Cellular systems studied:  tissue
Species studied:  human

Y192-p - Lck (human)
Modsite: NLDNGGFyIsPRItF SwissProt Entrez-Gene
Orthologous residues
Lck (human): Y192‑p, Lck iso3 (human): Y192‑p, Lck (mouse): Y192‑p, Lck (rat): Y192‑p
Characterization
Methods used to characterize site in vivo mass spectrometry
Disease tissue studied:  lung cancer, non-small cell lung cancer
Relevant cell lines - cell types - tissues:  lung
Cellular systems studied:  tissue
Species studied:  human

Y1415-p - MYH10 (human)
Modsite: LEEKALAyDKLEKTK SwissProt Entrez-Gene
Orthologous residues
MYH10 (human): Y1415‑p, MYH10 iso2 (human): Y1431‑p, MYH10 iso4 (human): Y1446‑p, MYH10 iso5 (human): Y1424‑p, MYH10 (mouse): Y1415‑p, MYH10 iso3 (mouse): Y1446‑p, MYH10 (rat): Y1415‑p, MYH10 (cow): Y1415‑p
Characterization
Methods used to characterize site in vivo mass spectrometry
Disease tissue studied:  lung cancer, non-small cell lung cancer
Relevant cell lines - cell types - tissues:  lung
Cellular systems studied:  tissue
Species studied:  human

S1943-p - MYH9 (human)
Modsite: RKGAGDGsDEEVDGK SwissProt Entrez-Gene
Orthologous residues
MYH9 (human): S1943‑p, MYH9 iso2 (human): S1365‑p, MYH9 (mouse): S1943‑p, MYH9 (rat): S1944‑p, MYH9 (cow): S1942‑p
Characterization
Methods used to characterize site in vivo mass spectrometry
Disease tissue studied:  lung cancer, non-small cell lung cancer
Relevant cell lines - cell types - tissues:  lung
Cellular systems studied:  tissue
Species studied:  human

S77-p - NDUFAF5 (human)
Modsite: YLKEEVGsRIADRVY SwissProt Entrez-Gene
Orthologous residues
NDUFAF5 (human): S77‑p, NDUFAF5 (mouse): S77‑p, NDUFAF5 (rat): S77‑p
Characterization
Methods used to characterize site in vivo mass spectrometry
Disease tissue studied:  lung cancer, non-small cell lung cancer
Relevant cell lines - cell types - tissues:  lung
Cellular systems studied:  tissue
Species studied:  human

Y182-p - P38A (human)
Modsite: tDDEMtGyVAtRWYR SwissProt Entrez-Gene
Orthologous residues
P38A (human): Y182‑p, P38A iso2 (human): Y182‑p, P38A (mouse): Y182‑p, P38A iso3 (mouse): Y182‑p, P38A (rat): Y182‑p, P38A (salmonid): Y183‑p
Characterization
Methods used to characterize site in vivo mass spectrometry
Disease tissue studied:  lung cancer, non-small cell lung cancer
Relevant cell lines - cell types - tissues:  lung
Cellular systems studied:  tissue
Species studied:  human

Y194-p - PAQR7 (human)
Modsite: IGSCYNKyIQkPGLL SwissProt Entrez-Gene
Orthologous residues
PAQR7 (human): Y194‑p, PAQR7 (mouse): Y193‑p
Characterization
Methods used to characterize site in vivo mass spectrometry
Disease tissue studied:  lung cancer, non-small cell lung cancer
Relevant cell lines - cell types - tissues:  lung
Cellular systems studied:  tissue
Species studied:  human

Y467-p - PIK3R1 (human)
Modsite: SREyDRLyEEytRTS SwissProt Entrez-Gene
Orthologous residues
PIK3R1 (human): Y467‑p, PIK3R1 iso2 (human): Y197‑p, PIK3R1 iso4 (human): Y467‑p, PIK3R1 (mouse): Y467‑p, PIK3R1 (rat): Y467‑p, PIK3R1 (cow): Y467‑p
Characterization
Methods used to characterize site in vivo mass spectrometry
Disease tissue studied:  lung cancer, non-small cell lung cancer
Relevant cell lines - cell types - tissues:  lung
Cellular systems studied:  tissue
Species studied:  human

Y849-p - PRP4 (human)
Modsite: ADNDItPyLVsRFyR SwissProt Entrez-Gene
Orthologous residues
PRP4 (human): Y849‑p, PRP4 (mouse): Y849‑p, PRP4 (rat): Y849‑p
Characterization
Methods used to characterize site in vivo mass spectrometry
Disease tissue studied:  lung cancer, non-small cell lung cancer
Relevant cell lines - cell types - tissues:  lung
Cellular systems studied:  tissue
Species studied:  human

Y705-p - STAT3 (human)
Modsite: DPGsAAPyLktKFIC SwissProt Entrez-Gene
Orthologous residues
STAT3 (human): Y705‑p, STAT3 iso2 (human): Y704‑p, STAT3 iso3 (human): Y705‑p, STAT3 (mouse): Y705‑p, STAT3 iso2 (mouse): Y705‑p, STAT3 iso3 (mouse): Y704‑p, STAT3 (rat): Y705‑p, STAT3 (cow): Y705‑p
Characterization
Methods used to characterize site in vivo mass spectrometry
Disease tissue studied:  lung cancer, non-small cell lung cancer
Relevant cell lines - cell types - tissues:  lung
Cellular systems studied:  tissue
Species studied:  human

Y704-p - STAT3 iso2 (human)
Modsite: ADPGAAPyLktKFIC SwissProt Entrez-Gene
Orthologous residues
STAT3 (human): Y705‑p, STAT3 iso2 (human): Y704‑p, STAT3 iso3 (human): Y705‑p, STAT3 (mouse): Y705‑p, STAT3 iso2 (mouse): Y705‑p, STAT3 iso3 (mouse): Y704‑p, STAT3 (rat): Y705‑p, STAT3 (cow): Y705‑p
Characterization
Methods used to characterize site in vivo mass spectrometry
Disease tissue studied:  lung cancer, non-small cell lung cancer
Relevant cell lines - cell types - tissues:  lung
Cellular systems studied:  tissue
Species studied:  human

T707-p - STAT3 iso2 (human)
Modsite: GAAPyLktKFICVtP SwissProt Entrez-Gene
Orthologous residues
STAT3 (human): T708‑p, STAT3 iso2 (human): T707‑p, STAT3 iso3 (human): T708‑p, STAT3 (mouse): T708‑p, STAT3 iso2 (mouse): T708‑p, STAT3 iso3 (mouse): T707‑p, STAT3 (rat): T708‑p, STAT3 (cow): T708‑p
Characterization
Methods used to characterize site in vivo mass spectrometry
Disease tissue studied:  lung cancer, non-small cell lung cancer
Relevant cell lines - cell types - tissues:  lung
Cellular systems studied:  tissue
Species studied:  human

Y483-p - tensin 2 (human)
Modsite: GPLDGsPyAQVQRPP SwissProt Entrez-Gene
Orthologous residues
tensin 2 (human): Y483‑p, tensin 2 iso2 (human): Y483‑p, tensin 2 iso4 (human): Y493‑p, tensin 2 (mouse): Y483‑p, tensin 2 (rat): Y483‑p
Characterization
Methods used to characterize site in vivo mass spectrometry
Disease tissue studied:  lung cancer, non-small cell lung cancer
Relevant cell lines - cell types - tissues:  lung
Cellular systems studied:  tissue
Species studied:  human

T108-p - TMEM263 (human)
Modsite: VVNkVPLtGkkKDKS SwissProt Entrez-Gene
Orthologous residues
TMEM263 (human): T108‑p, TMEM263 (mouse): S107‑p
Characterization
Methods used to characterize site in vivo mass spectrometry
Disease tissue studied:  lung cancer, non-small cell lung cancer
Relevant cell lines - cell types - tissues:  lung
Cellular systems studied:  tissue
Species studied:  human

Y222-p - Yes (human)
Modsite: RKLDNGGyyITtRAQ SwissProt Entrez-Gene
Orthologous residues
Yes (human): Y222‑p, Yes (mouse): Y220‑p, Yes (rat): Y220‑p
Characterization
Methods used to characterize site in vivo mass spectrometry
Disease tissue studied:  lung cancer, non-small cell lung cancer
Relevant cell lines - cell types - tissues:  lung
Cellular systems studied:  tissue
Species studied:  human