Curated Information
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Home > Curated Information Page > PubMed Id: 12812918
Lynch CJ, et al. (2003) Potential role of leucine metabolism in the leucine-signaling pathway involving mTOR. Am J Physiol Endocrinol Metab 285, E854-63 12812918
This page summarizes selected information from the record referenced above and curated into PhosphoSitePlus®, a comprehensive online resource for the study of protein post-translational modifications (NAR, 2015, 43:D512-20). To learn more about the scope of PhosphoSitePlus®, click here.
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S337-p - BCKDH E1-alpha (human)
Modsite: TYRIGHHstsDDssA SwissProt Entrez-Gene
Orthologous residues
BCKDH E1‑alpha (human): S337‑p, BCKDH E1‑alpha (mouse): S334‑p, BCKDH E1‑alpha (rat): S333‑p, BCKDH E1‑alpha (pig): S339‑p

S333-p - BCKDH E1-alpha (rat)
Modsite: TYRIGHHstsDDSSA SwissProt Entrez-Gene
Orthologous residues
BCKDH E1‑alpha (human): S337‑p, BCKDH E1‑alpha (mouse): S334‑p, BCKDH E1‑alpha (rat): S333‑p, BCKDH E1‑alpha (pig): S339‑p
Characterization
Methods used to characterize site in vivo phospho-antibody
Relevant cell lines - cell types - tissues:  adipocyte-adipose tissue, hepatocyte-liver, TREMK4
Cellular systems studied:  cell lines, tissue
Species studied:  rat
Upstream Regulation
Potential in vivo enzymes for site: 
Type Enzyme Evidence Notes
KINASE BCKDK (rat) genetic transfer of inducible upstream enzyme
Treatments, proteins and their effect on site modification: 
Treatments Referenced Treatments Manipulated Protein Referenced Protein Effect Notes
food deprivation increase
amino_acid_starvation increase
amino_acids decrease