Curated Information
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Home > Curated Information Page > PubMed Id: 22072751
Nakhaei P, et al. (2012) IκB kinase ε-dependent phosphorylation and degradation of X-linked inhibitor of apoptosis sensitizes cells to virus-induced apoptosis. J Virol 86, 726-37 22072751
This page summarizes selected information from the record referenced above and curated into PhosphoSitePlus®, a comprehensive online resource for the study of protein post-translational modifications (NAR, 2015, 43:D512-20). To learn more about the scope of PhosphoSitePlus®, click here.
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K322-ub - XIAP (human)
Modsite: DPWEQHAkWYPGCkY SwissProt Entrez-Gene
Orthologous residues
XIAP (human): K322‑ub, XIAP (mouse): K321‑ub, XIAP (rat): K321‑ub

K328-ub - XIAP (human)
Modsite: AkWYPGCkYLLEQkG SwissProt Entrez-Gene
Orthologous residues
XIAP (human): K328‑ub, XIAP (mouse): K327‑ub, XIAP (rat): K327‑ub

S430-p - XIAP (human)
Modsite: QDESSQtsLQkEIst SwissProt Entrez-Gene
Orthologous residues
XIAP (human): S430‑p, XIAP (mouse): S429‑p, XIAP (rat): S429‑p
Upstream Regulation
Potential in vivo enzymes for site: 
Type Enzyme Evidence Notes
KINASE IKKE (human)
Downstream Regulation
Effect of modification (function):  protein degradation, ubiquitination