Curated Information
Javascript is not enabled on this browser. This site will not work properly without Javascript.
PhosphoSitePlus Homepage PhosphoSitePlus® v6.7.1.1
Powered by Cell Signaling Technology
Home > Curated Information Page > PubMed Id: 21986494
Wu CS, et al. (2011) Type VI Adenylyl Cyclase Regulates Neurite Extension by Binding to Snapin and Snap25. Mol Cell Biol 31, 4874-86 21986494
This page summarizes selected information from the record referenced above and curated into PhosphoSitePlus®, a comprehensive online resource for the study of protein post-translational modifications (NAR, 2015, 43:D512-20). To learn more about the scope of PhosphoSitePlus®, click here.
Click on the protein name to open the protein page, and on the RSD number to open the site page.
Download

S50-p - SNAPIN (mouse)
Modsite: HVHAVREsQVELREQ SwissProt Entrez-Gene
Orthologous residues
SNAPIN (human): S50‑p, SNAPIN (mouse): S50‑p, SNAPIN (rat): S50‑p
Characterization
Methods used to characterize site in vivo western blotting
Disease tissue studied:  neuroblastoma
Relevant cell lines - cell types - tissues:  'neuron, hippocampal'-brain, Neuro-2a (neuron)
Cellular systems studied:  primary cells
Species studied:  rat
Downstream Regulation
Effect of modification (function):  molecular association, regulation
Effect of modification (process):  cell growth, inhibited
Modification regulates interactions with: 
Interacting molecule Interacting domains Effect Consequences (function) Consequences (process) Detection assays
SNAP-25 (mouse) Induces molecular association, regulation pull-down assay
Comments:  interaction between ADCY6 and Snap25 is mediated by Snapin; modulation of neurite outgrowth