Curated Information
Javascript is not enabled on this browser. This site will not work properly without Javascript.
PhosphoSitePlus Homepage PhosphoSitePlus® v6.5.9.1
Powered by Cell Signaling Technology
Home > Curated Information Page > PubMed Id: 21276607
No JH, et al. (2011) Activation of mTOR signaling pathway associated with adverse prognostic factors of epithelial ovarian cancer. Gynecol Oncol 121, 8-12 21276607
This page summarizes selected information from the record referenced above and curated into PhosphoSitePlus®, a comprehensive online resource for the study of protein post-translational modifications (NAR, 2015, 43:D512-20). To learn more about the scope of PhosphoSitePlus®, click here.
Click on the protein name to open the protein page, and on the RSD number to open the site page.
Download

T37-p - 4E-BP1 (human)
Modsite: PPGDysttPGGtLFs SwissProt Entrez-Gene
Orthologous residues
4E‑BP1 (human): T37‑p, 4E‑BP1 (mouse): T36‑p, 4E‑BP1 (rat): T36‑p, 4E‑BP1 (fruit fly): T37‑p, 4E‑BP1 (cow): T37‑p
Characterization
Methods used to characterize site in vivo phospho-antibody
Disease tissue studied:  ovarian cancer, ovarian epithelial carcinoma
Relevant cell lines - cell types - tissues:  ovary
Cellular systems studied:  tissue
Species studied:  human
Comments:  ovarian epithelial tissue
Associated Diseases
Diseases Alterations Comments
ovarian epithelial carcinoma increased

T46-p - 4E-BP1 (human)
Modsite: GGtLFsttPGGtRII SwissProt Entrez-Gene
Orthologous residues
4E‑BP1 (human): T46‑p, 4E‑BP1 (mouse): T45‑p, 4E‑BP1 (rat): T45‑p, 4E‑BP1 (fruit fly): T46‑p, 4E‑BP1 (cow): T46‑p
Characterization
Methods used to characterize site in vivo phospho-antibody
Disease tissue studied:  ovarian cancer, ovarian epithelial carcinoma
Relevant cell lines - cell types - tissues:  ovary
Cellular systems studied:  tissue
Species studied:  human
Comments:  ovarian epithelial tissue
Associated Diseases
Diseases Alterations Comments
ovarian epithelial carcinoma increased

S2448-p - mTOR (human)
Modsite: RsRtRtDsysAGQsV SwissProt Entrez-Gene
Orthologous residues
mTOR (human): S2448‑p, mTOR (mouse): S2448‑p, mTOR (rat): S2448‑p
Characterization
Methods used to characterize site in vivo phospho-antibody
Disease tissue studied:  ovarian cancer, ovarian epithelial carcinoma
Relevant cell lines - cell types - tissues:  ovary
Cellular systems studied:  tissue
Species studied:  human
Comments:  ovarian epithelial tissue
Associated Diseases
Diseases Alterations Comments
ovarian epithelial carcinoma increased

T412-p - p70S6K (human)
Modsite: NQVFLGFtyVAPsVL SwissProt Entrez-Gene
Orthologous residues
p70S6K (human): T412‑p, p70S6K iso2 (human): T389‑p, p70S6K (mouse): T412‑p, p70S6K (rat): T412‑p, p70S6K iso2 (rat): T389‑p, p70S6K (fruit fly): T398‑p
Characterization
Methods used to characterize site in vivo phospho-antibody
Disease tissue studied:  ovarian cancer, ovarian epithelial carcinoma
Relevant cell lines - cell types - tissues:  ovary
Cellular systems studied:  tissue
Species studied:  human
Comments:  ovarian epithelial tissue
Associated Diseases
Diseases Alterations Comments
ovarian epithelial carcinoma increased