Zhang X, et al. (2011) Two LXXLL motifs in the N terminus of Mps1 are required for Mps1 nuclear import during G(2)/M transition and sustained spindle checkpoint responses. Cell Cycle 10, 2742-50 21778823

This page summarizes selected information from the record referenced above and curated into PhosphoSitePlus®, a comprehensive online resource for the study of protein post-translational modifications (NAR, 2015, 43:D512-20). To learn more about the scope of PhosphoSitePlus®, click here.

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T12-p - TTK (human) ▲

Modsite: DLsGRELtIDsIMNk SwissProt Entrez-Gene Orthologous residues TTK (human): T12‑p, TTK iso2 (human): T12‑p, TTK (mouse): T12‑p, TTK iso2 (mouse): T12‑p, TTK (rat): T12‑p, TTK (frog): K12‑p Characterization Methods used to characterize site in vivo:  immunoassay, mutation of modification site Disease tissue studied:  colorectal cancer, colorectal carcinoma Relevant cell lines - cell types - tissues:  SW480 (intestinal) Cellular systems studied:  cell lines Species studied:  human

S15-p - TTK (human) ▲

Modsite: GRELtIDsIMNkVRD SwissProt Entrez-Gene Orthologous residues TTK (human): S15‑p, TTK iso2 (human): S15‑p, TTK (mouse): S15‑p, TTK iso2 (mouse): S15‑p, TTK (rat): S15‑p, TTK (frog): S15‑p Characterization Methods used to characterize site in vivo:  immunoassay, mutation of modification site Disease tissue studied:  colorectal cancer, colorectal carcinoma Relevant cell lines - cell types - tissues:  SW480 (intestinal) Cellular systems studied:  cell lines Species studied:  human

T33-p - TTK (human) ▲

Modsite: kFkNEDLtDELsLNK SwissProt Entrez-Gene Orthologous residues TTK (human): T33‑p, TTK iso2 (human): T33‑p, TTK (mouse): T32‑p, TTK iso2 (mouse): T32‑p, TTK (rat): T32‑p, TTK (frog): T34‑p Characterization Methods used to characterize site in vivo:  immunoassay, mutation of modification site Disease tissue studied:  colorectal cancer, colorectal carcinoma Relevant cell lines - cell types - tissues:  SW480 (intestinal) Cellular systems studied:  cell lines Species studied:  human

S37-p - TTK (human) ▲

Modsite: EDLtDELsLNKISAD SwissProt Entrez-Gene Orthologous residues TTK (human): S37‑p, TTK iso2 (human): S37‑p, TTK (mouse): S36‑p, TTK iso2 (mouse): S36‑p, TTK (rat): N36‑p, TTK (frog): T38‑p Characterization Methods used to characterize site in vivo:  immunoassay, mutation of modification site Disease tissue studied:  colorectal cancer, colorectal carcinoma Relevant cell lines - cell types - tissues:  SW480 (intestinal) Cellular systems studied:  cell lines Species studied:  human

S80-p - TTK (human) ▲

Modsite: EkNSVPLsDALLNkL SwissProt Entrez-Gene Orthologous residues TTK (human): S80‑p, TTK iso2 (human): S80‑p, TTK (mouse): N76‑p, TTK iso2 (mouse): N76‑p, TTK (rat): N76‑p, TTK (frog): D81‑p Characterization Methods used to characterize site in vivo:  immunoassay, mutation of modification site Disease tissue studied:  colorectal cancer, colorectal carcinoma Relevant cell lines - cell types - tissues:  SW480 (intestinal) Cellular systems studied:  cell lines Species studied:  human Downstream Regulation Effect of modification (function):  intracellular localization