Ren K, et al. (2011) CK2 phosphorylates AP-2α and increases its transcriptional activity. BMB Rep 44, 490-5 21777522

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S429-p - AP-2 alpha (human) ▲

Modsite: TDNNAKssDKEEKHR SwissProt Entrez-Gene Orthologous residues AP‑2 alpha (human): S429‑p, AP‑2 alpha iso2 (human): S423‑p, AP‑2 alpha (mouse): S429‑p, AP‑2 alpha (rat): S429‑p Characterization Methods used to characterize site in vivo:  immunoprecipitation, microscopy-colocalization with upstream kinase Relevant cell lines - cell types - tissues:  293FT Cellular systems studied:  cell lines Species studied:  human Enzymes shown to modify site in vitro:  Type Enzyme KINASE CK2A1 (human) Upstream Regulation Potential in vivo enzymes for site:  Type Enzyme Evidence Notes KINASE CK2A1 (human) co-immunoprecipitation, microscopy-colocalization, pharmacological inhibitor of upstream enzyme Comments:  CK2B participates in complex Downstream Regulation Effect of modification (function):  protein stabilization Effect of modification (process):  transcription, induced Comments:  induces AP-2 alpha transcription