Curated Information
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Home > Curated Information Page > PubMed Id: 21771582
Hüttemann M, et al. (2012) Regulation of mitochondrial respiration and apoptosis through cell signaling: Cytochrome c oxidase and cytochrome c in ischemia/reperfusion injury and inflammation. Biochim Biophys Acta 1817, 598-609 21771582
This page summarizes selected information from the record referenced above and curated into PhosphoSitePlus®, a comprehensive online resource for the study of protein post-translational modifications (NAR, 2015, 43:D512-20). To learn more about the scope of PhosphoSitePlus®, click here.
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Y304-p - COX1 (cow)
Modsite: MDVDTRAyFTSATMI SwissProt
Orthologous residues
COX1 (human): Y304‑p, COX1 (mouse): Y304‑p, COX1 (rat): Y304‑p, COX1 (rabbit): Y304‑p, COX1 (cow): Y304‑p
Characterization
Methods used to characterize site in vivo mass spectrometry, mutation of modification site
Relevant cell lines - cell types - tissues:  liver
Cellular systems studied:  tissue
Species studied:  cow
Upstream Regulation
Treatments, proteins and their effect on site modification: 
Treatments Referenced Treatments Manipulated Protein Referenced Protein Effect Notes
NaF increase
vanadate increase

S126-p - COX2 (cow)
Modsite: DSYMIPTsELKPGEL SwissProt Entrez-Gene
Orthologous residues
COX2 (human): L126‑p, COX2 (mouse): N126‑p, COX2 (rat): N126‑p, COX2 (cow): S126‑p
Characterization
Methods used to characterize site in vivo mass spectrometry
Relevant cell lines - cell types - tissues:  heart
Cellular systems studied:  tissue
Species studied:  cow

Y49-p - CYCS (cow)
Modsite: GQAPGFSyTDANkNk SwissProt Entrez-Gene
Orthologous residues
CYCS (human): Y49‑p, CYCS (mouse): Y49‑p, CYCS (rat): Y49‑p, CYCS (pig): Y49‑p, CYCS (cow): Y49‑p, CYCS (horse): Y49‑p
Characterization
Methods used to characterize site in vivo mass spectrometry, mutation of modification site
Relevant cell lines - cell types - tissues:  liver
Cellular systems studied:  tissue
Species studied:  cow

Y98-p - CYCS (cow)
Modsite: EREDLIAyLkkATNE SwissProt Entrez-Gene
Orthologous residues
CYCS (human): Y98‑p, CYCS (mouse): Y98‑p, CYCS (rat): Y98‑p, CYCS (pig): Y98‑p, CYCS (cow): Y98‑p, CYCS (horse): Y98‑p
Characterization
Methods used to characterize site in vivo mass spectrometry
Relevant cell lines - cell types - tissues:  heart
Cellular systems studied:  tissue
Species studied:  cow