Curated Information
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Home > Curated Information Page > PubMed Id: 21658608
Hubbi ME, Luo W, Baek JH, Semenza GL (2011) MCM proteins are negative regulators of hypoxia-inducible factor 1. Mol Cell 42, 700-12 21658608
This page summarizes selected information from the record referenced above and curated into PhosphoSitePlus®, a comprehensive online resource for the study of protein post-translational modifications (NAR, 2015, 43:D512-20). To learn more about the scope of PhosphoSitePlus®, click here.
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S112-p - MCM3 (human)
Modsite: SFGSKHVsPRTLTSC SwissProt Entrez-Gene
Orthologous residues
MCM3 (human): S112‑p, MCM3 iso2 (human): S157‑p, MCM3 (mouse): S112‑p, MCM3 (rat): S112‑p
Characterization
Methods used to characterize site in vivo mutation of modification site
Relevant cell lines - cell types - tissues:  HEK293T (epithelial)
Cellular systems studied:  cell lines
Species studied:  human
Downstream Regulation
Effect of modification (function):  molecular association, regulation
Modification regulates interactions with: 
Interacting molecule Interacting domains Effect Consequences (function) Consequences (process) Detection assays
MCM7 (human) Induces co-immunoprecipitation