Faus H, Haendler B (2008) Androgen receptor acetylation sites differentially regulate gene control. J Cell Biochem 104, 511-24 18022799

This page summarizes selected information from the record referenced above and curated into PhosphoSitePlus®, a comprehensive online resource for the study of protein post-translational modifications (NAR, 2015, 43:D512-20). To learn more about the scope of PhosphoSitePlus®, click here.

Click on the protein name to open the protein page, and on the RSD number to open the site page.

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K631-ac - AR (human) ▲

Modsite: GMTLGARkLkkLGNL SwissProt Entrez-Gene Orthologous residues AR (human): K631‑ac, AR iso3 (human): ‑, AR (mouse): K610‑ac, AR (rat): K613‑ac Characterization Methods used to characterize site in vivo:  mutation of modification site Disease tissue studied:  prostate cancer Relevant cell lines - cell types - tissues:  CV1 (fibroblast), PC3 (prostate cell) Cellular systems studied:  cell lines Species studied:  green monkey, human Downstream Regulation Effect of modification (process):  transcription, altered Comments:  has differential effect on different promoters

K633-ac - AR (human) ▲

Modsite: TLGARkLkkLGNLKL SwissProt Entrez-Gene Orthologous residues AR (human): K633‑ac, AR iso3 (human): ‑, AR (mouse): K612‑ac, AR (rat): K615‑ac Characterization Methods used to characterize site in vivo:  mutation of modification site Disease tissue studied:  prostate cancer Relevant cell lines - cell types - tissues:  CV1 (fibroblast), PC3 (prostate cell) Cellular systems studied:  cell lines Species studied:  green monkey, human Downstream Regulation Effect of modification (process):  transcription, altered Comments:  has differential effect on different promoters

K634-ac - AR (human) ▲

Modsite: LGARkLkkLGNLKLQ SwissProt Entrez-Gene Orthologous residues AR (human): K634‑ac, AR iso3 (human): ‑, AR (mouse): K613‑ac, AR (rat): K616‑ac Characterization Methods used to characterize site in vivo:  mutation of modification site Disease tissue studied:  prostate cancer Relevant cell lines - cell types - tissues:  CV1 (fibroblast), PC3 (prostate cell) Cellular systems studied:  cell lines Species studied:  green monkey, human Downstream Regulation Effect of modification (process):  transcription, altered Comments:  has differential effect on different promoters