Oh C, et al. (2022) Neutrophil inflammasomes sense the subcellular delivery route of translocated bacterial effectors and toxins. Cell Rep 41, 111688 36417874

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S205-p - pyrin (mouse) ▲

Modsite: AQLRRNVsSAGRLQG SwissProt Entrez-Gene Orthologous residues pyrin (human): S208‑p, pyrin (mouse): S205‑p, pyrin (rat): Q204‑p Characterization Methods used to characterize site in vivo:  phospho-antibody, western blotting Relevant cell lines - cell types - tissues:  macrophage-bone marrow, neutrophil Cellular systems studied:  primary cells, tissue Species studied:  mouse Upstream Regulation Treatments, proteins and their effect on site modification:  Treatments Referenced Treatments Manipulated Protein Referenced Protein Effect Notes bacterial infection decrease Y. pseudotuberculosis Delta yopM infection Clostridium_toxin_B decrease