Curated Information
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Home > Curated Information Page > PubMed Id: 8639568
Joyal JL, Crimmins DL, Thoma RS, Sacks DB (1996) Identification of insulin-stimulated phosphorylation sites on calmodulin. Biochemistry 35, 6267-75 8639568
This page summarizes selected information from the record referenced above and curated into PhosphoSitePlus®, a comprehensive online resource for the study of protein post-translational modifications (NAR, 2015, 43:D512-20). To learn more about the scope of PhosphoSitePlus®, click here.
Click on the protein name to open the protein page, and on the RSD number to open the site page.
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T80-p - Calmodulin (rat)
Modsite: MARKMkDtDsEEEIR SwissProt Entrez-Gene
Orthologous residues
Calmodulin (human): T80‑p, Calmodulin (mouse): T80‑p, Calmodulin (rat): T80‑p, Calmodulin (chicken): T80‑p, Calmodulin (sheep): T80‑p, Calmodulin (cow): T80‑p

S82-p - Calmodulin (rat)
Modsite: RKMkDtDsEEEIREA SwissProt Entrez-Gene
Orthologous residues
Calmodulin (human): S82‑p, Calmodulin (mouse): S82‑p, Calmodulin (rat): S82‑p, Calmodulin (chicken): S82‑p, Calmodulin (sheep): S82‑p, Calmodulin (cow): S82‑p

Y100-p - Calmodulin (rat)
Modsite: FDkDGNGyIsAAELR SwissProt Entrez-Gene
Orthologous residues
Calmodulin (human): Y100‑p, Calmodulin (mouse): Y100‑p, Calmodulin (rat): Y100‑p, Calmodulin (chicken): Y100‑p, Calmodulin (sheep): Y100‑p, Calmodulin (cow): Y100‑p
Characterization
Methods used to characterize site in vivo phosphopeptide mapping
Relevant cell lines - cell types - tissues:  CHO (fibroblast) [EphB1 (human), transfection], CHO (fibroblast) [INSR (human)]
Cellular systems studied:  cell lines
Species studied:  hamster
Enzymes shown to modify site in vitro
Type Enzyme
KINASE INSR (human)
Upstream Regulation
Treatments, proteins and their effect on site modification: 
Treatments Referenced Treatments Manipulated Protein Referenced Protein Effect Notes
insulin increase

S102-p - Calmodulin (rat)
Modsite: kDGNGyIsAAELRHV SwissProt Entrez-Gene
Orthologous residues
Calmodulin (human): S102‑p, Calmodulin (mouse): S102‑p, Calmodulin (rat): S102‑p, Calmodulin (chicken): S102‑p, Calmodulin (sheep): S102‑p, Calmodulin (cow): S102‑p

T118-p - Calmodulin (rat)
Modsite: TNLGEkLtDEEVDEM SwissProt Entrez-Gene
Orthologous residues
Calmodulin (human): T118‑p, Calmodulin (mouse): T118‑p, Calmodulin (rat): T118‑p, Calmodulin (chicken): T118‑p, Calmodulin (sheep): T118‑p, Calmodulin (cow): T118‑p

Y139-p - Calmodulin (rat)
Modsite: DGDGQVNyEEFVQMM SwissProt Entrez-Gene
Orthologous residues
Calmodulin (human): Y139‑p, Calmodulin (mouse): Y139‑p, Calmodulin (rat): Y139‑p, Calmodulin (chicken): Y139‑p, Calmodulin (sheep): Y139‑p, Calmodulin (cow): Y139‑p
Characterization
Methods used to characterize site in vivo phosphopeptide mapping
Relevant cell lines - cell types - tissues:  CHO (fibroblast) [EphB1 (human), transfection]
Cellular systems studied:  cell lines
Species studied:  hamster
Enzymes shown to modify site in vitro
Type Enzyme
KINASE INSR (human)
Upstream Regulation
Treatments, proteins and their effect on site modification: 
Treatments Referenced Treatments Manipulated Protein Referenced Protein Effect Notes
insulin increase