Quadroni M, James P, Carafoli E (1994) Isolation of phosphorylated calmodulin from rat liver and identification of the in vivo phosphorylation sites. J Biol Chem 269, 16116-22 8206911

This page summarizes selected information from the record referenced above and curated into PhosphoSitePlus®, a comprehensive online resource for the study of protein post-translational modifications (NAR, 2015, 43:D512-20). To learn more about the scope of PhosphoSitePlus®, click here.

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T80-p - Calmodulin (rat) ▲

Modsite: MARKMkDtDsEEEIR SwissProt Entrez-Gene Orthologous residues Calmodulin (human): T80‑p, Calmodulin (mouse): T80‑p, Calmodulin (rat): T80‑p, Calmodulin (chicken): T80‑p, Calmodulin (sheep): T80‑p, Calmodulin (cow): T80‑p Characterization Methods used to characterize site in vivo:  mass spectrometry Relevant cell lines - cell types - tissues:  liver Cellular systems studied:  tissue Species studied:  rat Comments:  Approximately 15% of CaM in the cell is phosphorylated. Enzymes shown to modify site in vitro:  Type Enzyme KINASE CK2A1 (rat) Downstream Regulation Effect of modification (function):  activity, inhibited Comments:  Calmodulin phosphorylated by CKII in vitro showed reduced activation of erythrocyte plasma membrane Ca2+ pump.

S82-p - Calmodulin (rat) ▲

Modsite: RKMkDtDsEEEIREA SwissProt Entrez-Gene Orthologous residues Calmodulin (human): S82‑p, Calmodulin (mouse): S82‑p, Calmodulin (rat): S82‑p, Calmodulin (chicken): S82‑p, Calmodulin (sheep): S82‑p, Calmodulin (cow): S82‑p Characterization Methods used to characterize site in vivo:  mass spectrometry Relevant cell lines - cell types - tissues:  liver Cellular systems studied:  tissue Species studied:  rat Comments:  Approximately 15% of CaM in the cell is phosphorylated. Enzymes shown to modify site in vitro:  Type Enzyme KINASE CK2A1 (rat) Downstream Regulation Effect of modification (function):  activity, inhibited Comments:  Calmodulin phosphorylated by CKII in vitro showed reduced activation of erythrocyte plasma membrane Ca2+ pump.

S102-p - Calmodulin (rat) ▲

Modsite: kDGNGyIsAAELRHV SwissProt Entrez-Gene Orthologous residues Calmodulin (human): S102‑p, Calmodulin (mouse): S102‑p, Calmodulin (rat): S102‑p, Calmodulin (chicken): S102‑p, Calmodulin (sheep): S102‑p, Calmodulin (cow): S102‑p Characterization Methods used to characterize site in vivo:  mass spectrometry Relevant cell lines - cell types - tissues:  liver Cellular systems studied:  tissue Species studied:  rat Comments:  Approximately 15% of CaM in the cell is phosphorylated. Enzymes shown to modify site in vitro:  Type Enzyme KINASE CK2A1 (rat) Downstream Regulation Effect of modification (function):  activity, inhibited Comments:  Calmodulin phosphorylated by CKII in vitro showed reduced activation of erythrocyte plasma membrane Ca2+ pump.