Curated Information
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Home > Curated Information Page > PubMed Id: 33212041
Wang Y, et al. (2020) Identification of a novel non-ATP-competitive protein kinase inhibitor of PGK1 from marine nature products. Biochem Pharmacol 183, 114343 33212041
This page summarizes selected information from the record referenced above and curated into PhosphoSitePlus®, a comprehensive online resource for the study of protein post-translational modifications (NAR, 2015, 43:D512-20). To learn more about the scope of PhosphoSitePlus®, click here.
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T338-p - PDHK1 (human)
Modsite: LFNYMyStAPRPRVE SwissProt Entrez-Gene
Orthologous residues
PDHK1 (human): T338‑p, PDHK1 (mouse): T336‑p, PDHK1 (rat): T336‑p
Upstream Regulation
Potential in vivo enzymes for site: 
Type Enzyme Evidence Notes
KINASE PGK1 (human) transfection of wild-type enzyme, activation of upstream enzyme, pharmacological inhibitor of upstream enzyme, siRNA inhibition of enzyme
Treatments, proteins and their effect on site modification: 
Treatments Referenced Treatments Manipulated Protein Referenced Protein Effect Notes
CoCL2 increase
EGF increase
siRNA decrease PGK1 siRNA
GQQ-792 decrease
GQQ-792 CoCL2 inhibit treatment-induced increase
GQQ-792 EGF inhibit treatment-induced increase