Bartelt-Kirbach B, et al. (2020) HspB5/αB-crystallin phosphorylation at S45 and S59 is essential for protection of the dendritic tree of rat hippocampal neurons. J Neurochem 33220080

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S19-p - CRYAB (rat) ▲

Modsite: RPFFPFHsPSRLFDQ SwissProt Entrez-Gene Orthologous residues CRYAB (human): S19‑p, CRYAB (mouse): S19‑p, CRYAB (rat): S19‑p, CRYAB (rabbit): S19‑p, CRYAB (pig): S19‑p, CRYAB (cow): S19‑p Characterization Methods used to characterize site in vivo:  mutation of modification site Relevant cell lines - cell types - tissues:  'neuron, hippocampal, CA1 pyramidal'-brain, neuron-'brain, hippocampus' Cellular systems studied:  primary cultured cells Species studied:  mouse, rat Downstream Regulation Effect of modification (function):  protein degradation

S45-p - CRYAB (rat) ▲

Modsite: FSTATSLsPFYLRPP SwissProt Entrez-Gene Orthologous residues CRYAB (human): S45‑p, CRYAB (mouse): S45‑p, CRYAB (rat): S45‑p, CRYAB (rabbit): S45‑p, CRYAB (pig): S45‑p, CRYAB (cow): S45‑p Characterization Methods used to characterize site in vivo:  mutation of modification site Relevant cell lines - cell types - tissues:  'neuron, hippocampal, CA1 pyramidal'-brain, neuron-'brain, hippocampus' Cellular systems studied:  primary cultured cells Species studied:  mouse, rat Downstream Regulation Effect of modification (function):  protein degradation Effect of modification (process):  cytoskeletal reorganization Comments:  regulates the dentritic functions of HspB5

S59-p - CRYAB (rat) ▲

Modsite: PSFLRAPsWIDTGLS SwissProt Entrez-Gene Orthologous residues CRYAB (human): S59‑p, CRYAB (mouse): S59‑p, CRYAB (rat): S59‑p, CRYAB (rabbit): S59‑p, CRYAB (pig): S59‑p, CRYAB (cow): S59‑p Characterization Methods used to characterize site in vivo:  mutation of modification site Relevant cell lines - cell types - tissues:  'neuron, hippocampal, CA1 pyramidal'-brain, neuron-'brain, hippocampus' Cellular systems studied:  primary cultured cells Species studied:  mouse, rat Downstream Regulation Effect of modification (function):  protein degradation Effect of modification (process):  cytoskeletal reorganization Comments:  regulates the dentritic functions of HspB5