Zárraga-Granados G, et al. (2020) The nuclear receptor NR4A1 is regulated by SUMO modification to induce autophagic cell death. PLoS One 15, e0222072 32210435

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T143-p - Nur77 (human) ▲

Modsite: CSAPsPStPSFQPPQ SwissProt Entrez-Gene Orthologous residues Nur77 (human): T143‑p, Nur77 iso2 (human): T156‑p, Nur77 (mouse): T145‑p, Nur77 (rat): T142‑p Characterization Methods used to characterize site in vivo:  mutation of modification site, phospho-antibody, western blotting Relevant cell lines - cell types - tissues:  293 (epithelial) Cellular systems studied:  cell lines Species studied:  human Upstream Regulation Treatments, proteins and their effect on site modification:  Treatments Referenced Treatments Manipulated Protein Referenced Protein Effect Notes substance_P increase Downstream Regulation Effect of modification (function):  intracellular localization, sumoylation Effect of modification (process):  autophagy, induced