Curated Information
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Home > Curated Information Page > PubMed Id: 21215796
Castillo C, et al. (2011) The N-methyl-D-aspartate-evoked cytoplasmic calcium increase in adult rat dorsal root ganglion neuronal somata was potentiated by substance P pretreatment in a protein kinase C-dependent manner. Neuroscience 177, 308-20 21215796
This page summarizes selected information from the record referenced above and curated into PhosphoSitePlus®, a comprehensive online resource for the study of protein post-translational modifications (NAR, 2015, 43:D512-20). To learn more about the scope of PhosphoSitePlus®, click here.
Click on the protein name to open the protein page, and on the RSD number to open the site page.
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S1303-p - NMDAR2B (rat)
Modsite: NKLRRQHsyDtFVDL SwissProt Entrez-Gene
Orthologous residues
NMDAR2B (human): S1303‑p, NMDAR2B (mouse): S1303‑p, NMDAR2B (rat): S1303‑p
Characterization
Methods used to characterize site in vivo phospho-antibody, western blotting
Relevant cell lines - cell types - tissues:  brain
Cellular systems studied:  tissue
Species studied:  rat

Y1472-p - NMDAR2B (rat)
Modsite: GSSNGHVyEKLssIE SwissProt Entrez-Gene
Orthologous residues
NMDAR2B (human): Y1474‑p, NMDAR2B (mouse): Y1472‑p, NMDAR2B (rat): Y1472‑p
Characterization
Methods used to characterize site in vivo phospho-antibody, western blotting
Relevant cell lines - cell types - tissues:  brain
Cellular systems studied:  tissue
Species studied:  rat
Upstream Regulation
Treatments, proteins and their effect on site modification: 
Treatments Referenced Treatments Manipulated Protein Referenced Protein Effect Notes
NMDA increase
substance_P increase
substance_P NMDA increase
bisindolylmaleimide NMDA, substance_P inhibit treatment-induced increase