Curated Information
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Home > Curated Information Page > PubMed Id: 20977274
Yoder AR, Stone MD, Griffin TJ, Potter LR (2010) Mass spectrometric identification of phosphorylation sites in guanylyl cyclase A and B. Biochemistry 49, 10137-45 20977274
This page summarizes selected information from the record referenced above and curated into PhosphoSitePlus®, a comprehensive online resource for the study of protein post-translational modifications (NAR, 2015, 43:D512-20). To learn more about the scope of PhosphoSitePlus®, click here.
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S519-p - ANPA (human)
Modsite: WEDVEPSsLERHLRS SwissProt Entrez-Gene
Orthologous residues
ANPA (human): S519‑p, ANPA (mouse): S515‑p, ANPA (rat): S515‑p
Characterization
Methods used to characterize site in vivo mass spectrometry
Relevant cell lines - cell types - tissues:  293 (epithelial)
Cellular systems studied:  cell lines
Species studied:  human

S529-p - ANPA (human)
Modsite: RHLRSAGsRLtLsGR SwissProt Entrez-Gene
Orthologous residues
ANPA (human): S529‑p, ANPA (mouse): S525‑p, ANPA (rat): S525‑p
Characterization
Methods used to characterize site in vivo mass spectrometry
Relevant cell lines - cell types - tissues:  293 (epithelial)
Cellular systems studied:  cell lines
Species studied:  human

T532-p - ANPA (human)
Modsite: RSAGsRLtLsGRGsN SwissProt Entrez-Gene
Orthologous residues
ANPA (human): T532‑p, ANPA (mouse): T528‑p, ANPA (rat): T528‑p
Characterization
Methods used to characterize site in vivo mass spectrometry
Relevant cell lines - cell types - tissues:  293 (epithelial)
Cellular systems studied:  cell lines
Species studied:  human

S534-p - ANPA (human)
Modsite: AGsRLtLsGRGsNYG SwissProt Entrez-Gene
Orthologous residues
ANPA (human): S534‑p, ANPA (mouse): S530‑p, ANPA (rat): S530‑p
Characterization
Methods used to characterize site in vivo mass spectrometry
Relevant cell lines - cell types - tissues:  293 (epithelial)
Cellular systems studied:  cell lines
Species studied:  human

S538-p - ANPA (human)
Modsite: LtLsGRGsNYGsLLt SwissProt Entrez-Gene
Orthologous residues
ANPA (human): S538‑p, ANPA (mouse): S534‑p, ANPA (rat): S534‑p
Characterization
Methods used to characterize site in vivo mass spectrometry
Relevant cell lines - cell types - tissues:  293 (epithelial)
Cellular systems studied:  cell lines
Species studied:  human

S513-p - ANPB (human)
Modsite: RYHKGAGsRLtLsLR SwissProt Entrez-Gene
Orthologous residues
ANPB (human): S513‑p, ANPB iso2 (human): S513‑p, ANPB (mouse): S513‑p, ANPB (rat): S513‑p
Characterization
Methods used to characterize site in vivo mass spectrometry
Relevant cell lines - cell types - tissues:  293 (epithelial)
Cellular systems studied:  cell lines
Species studied:  human

T516-p - ANPB (human)
Modsite: KGAGsRLtLsLRGSs SwissProt Entrez-Gene
Orthologous residues
ANPB (human): T516‑p, ANPB iso2 (human): T516‑p, ANPB (mouse): T516‑p, ANPB (rat): T516‑p
Characterization
Methods used to characterize site in vivo mass spectrometry
Relevant cell lines - cell types - tissues:  293 (epithelial)
Cellular systems studied:  cell lines
Species studied:  human

S518-p - ANPB (human)
Modsite: AGsRLtLsLRGSsYG SwissProt Entrez-Gene
Orthologous residues
ANPB (human): S518‑p, ANPB iso2 (human): S518‑p, ANPB (mouse): S518‑p, ANPB (rat): S518‑p
Characterization
Methods used to characterize site in vivo mass spectrometry
Relevant cell lines - cell types - tissues:  293 (epithelial)
Cellular systems studied:  cell lines
Species studied:  human

S523-p - ANPB (human)
Modsite: tLsLRGSsYGsLMtA SwissProt Entrez-Gene
Orthologous residues
ANPB (human): S523‑p, ANPB iso2 (human): S523‑p, ANPB (mouse): S523‑p, ANPB (rat): S523‑p
Characterization
Methods used to characterize site in vivo mass spectrometry
Relevant cell lines - cell types - tissues:  293 (epithelial)
Cellular systems studied:  cell lines
Species studied:  human

S526-p - ANPB (human)
Modsite: LRGSsYGsLMtAHGK SwissProt Entrez-Gene
Orthologous residues
ANPB (human): S526‑p, ANPB iso2 (human): S526‑p, ANPB (mouse): S526‑p, ANPB (rat): S526‑p
Characterization
Methods used to characterize site in vivo mass spectrometry
Relevant cell lines - cell types - tissues:  293 (epithelial)
Cellular systems studied:  cell lines
Species studied:  human

T529-p - ANPB (human)
Modsite: SsYGsLMtAHGKYQI SwissProt Entrez-Gene
Orthologous residues
ANPB (human): T529‑p, ANPB iso2 (human): T529‑p, ANPB (mouse): T529‑p, ANPB (rat): T529‑p
Characterization
Methods used to characterize site in vivo mass spectrometry
Relevant cell lines - cell types - tissues:  293 (epithelial)
Cellular systems studied:  cell lines
Species studied:  human

S515-p - ANPA (rat)
Modsite: WEDLQPSsLERHLRS SwissProt Entrez-Gene
Orthologous residues
ANPA (human): S519‑p, ANPA (mouse): S515‑p, ANPA (rat): S515‑p
Characterization
Methods used to characterize site in vivo mass spectrometry
Relevant cell lines - cell types - tissues:  293 (epithelial)
Cellular systems studied:  cell lines
Species studied:  human
Downstream Regulation
Effect of modification (function):  enzymatic activity, inhibited

S525-p - ANPA (rat)
Modsite: RHLRSAGsRLtLsGR SwissProt Entrez-Gene
Orthologous residues
ANPA (human): S529‑p, ANPA (mouse): S525‑p, ANPA (rat): S525‑p
Characterization
Methods used to characterize site in vivo mass spectrometry
Relevant cell lines - cell types - tissues:  293 (epithelial)
Cellular systems studied:  cell lines
Species studied:  human

T528-p - ANPA (rat)
Modsite: RSAGsRLtLsGRGsN SwissProt Entrez-Gene
Orthologous residues
ANPA (human): T532‑p, ANPA (mouse): T528‑p, ANPA (rat): T528‑p
Characterization
Methods used to characterize site in vivo mass spectrometry
Relevant cell lines - cell types - tissues:  293 (epithelial)
Cellular systems studied:  cell lines
Species studied:  human

S530-p - ANPA (rat)
Modsite: AGsRLtLsGRGsNYG SwissProt Entrez-Gene
Orthologous residues
ANPA (human): S534‑p, ANPA (mouse): S530‑p, ANPA (rat): S530‑p
Characterization
Methods used to characterize site in vivo mass spectrometry
Relevant cell lines - cell types - tissues:  293 (epithelial)
Cellular systems studied:  cell lines
Species studied:  human

S534-p - ANPA (rat)
Modsite: LtLsGRGsNYGsLLt SwissProt Entrez-Gene
Orthologous residues
ANPA (human): S538‑p, ANPA (mouse): S534‑p, ANPA (rat): S534‑p
Characterization
Methods used to characterize site in vivo mass spectrometry
Relevant cell lines - cell types - tissues:  293 (epithelial)
Cellular systems studied:  cell lines
Species studied:  human

S538-p - ANPA (rat)
Modsite: GRGsNYGsLLtTEGQ SwissProt Entrez-Gene
Orthologous residues
ANPA (human): S542‑p, ANPA (mouse): S538‑p, ANPA (rat): S538‑p
Characterization
Methods used to characterize site in vivo mass spectrometry
Relevant cell lines - cell types - tissues:  293 (epithelial)
Cellular systems studied:  cell lines
Species studied:  human

T541-p - ANPA (rat)
Modsite: sNYGsLLtTEGQFQV SwissProt Entrez-Gene
Orthologous residues
ANPA (human): T545‑p, ANPA (mouse): T541‑p, ANPA (rat): T541‑p
Characterization
Methods used to characterize site in vivo mass spectrometry
Relevant cell lines - cell types - tissues:  293 (epithelial)
Cellular systems studied:  cell lines
Species studied:  human

S513-p - ANPB (rat)
Modsite: RYHKGAGsRLtLsLR SwissProt Entrez-Gene
Orthologous residues
ANPB (human): S513‑p, ANPB iso2 (human): S513‑p, ANPB (mouse): S513‑p, ANPB (rat): S513‑p
Characterization
Methods used to characterize site in vivo mass spectrometry, mutation of modification site
Relevant cell lines - cell types - tissues:  293 (epithelial)
Cellular systems studied:  cell lines
Species studied:  human

T516-p - ANPB (rat)
Modsite: KGAGsRLtLsLRGSs SwissProt Entrez-Gene
Orthologous residues
ANPB (human): T516‑p, ANPB iso2 (human): T516‑p, ANPB (mouse): T516‑p, ANPB (rat): T516‑p
Characterization
Methods used to characterize site in vivo mass spectrometry, mutation of modification site
Relevant cell lines - cell types - tissues:  293 (epithelial)
Cellular systems studied:  cell lines
Species studied:  human

S518-p - ANPB (rat)
Modsite: AGsRLtLsLRGSsYG SwissProt Entrez-Gene
Orthologous residues
ANPB (human): S518‑p, ANPB iso2 (human): S518‑p, ANPB (mouse): S518‑p, ANPB (rat): S518‑p
Characterization
Methods used to characterize site in vivo mass spectrometry, mutation of modification site
Relevant cell lines - cell types - tissues:  293 (epithelial)
Cellular systems studied:  cell lines
Species studied:  human

S523-p - ANPB (rat)
Modsite: tLsLRGSsYGsLMtA SwissProt Entrez-Gene
Orthologous residues
ANPB (human): S523‑p, ANPB iso2 (human): S523‑p, ANPB (mouse): S523‑p, ANPB (rat): S523‑p
Characterization
Methods used to characterize site in vivo mass spectrometry, mutation of modification site
Relevant cell lines - cell types - tissues:  293 (epithelial)
Cellular systems studied:  cell lines
Species studied:  human

S526-p - ANPB (rat)
Modsite: LRGSsYGsLMtAHGK SwissProt Entrez-Gene
Orthologous residues
ANPB (human): S526‑p, ANPB iso2 (human): S526‑p, ANPB (mouse): S526‑p, ANPB (rat): S526‑p
Characterization
Methods used to characterize site in vivo mass spectrometry, mutation of modification site
Relevant cell lines - cell types - tissues:  293 (epithelial)
Cellular systems studied:  cell lines
Species studied:  human

T529-p - ANPB (rat)
Modsite: SsYGsLMtAHGKYQI SwissProt Entrez-Gene
Orthologous residues
ANPB (human): T529‑p, ANPB iso2 (human): T529‑p, ANPB (mouse): T529‑p, ANPB (rat): T529‑p
Characterization
Methods used to characterize site in vivo mass spectrometry, mutation of modification site
Relevant cell lines - cell types - tissues:  293 (epithelial)
Cellular systems studied:  cell lines
Species studied:  human
Downstream Regulation
Effect of modification (function):  enzymatic activity, induced