Curated Information
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Home > Curated Information Page > PubMed Id: 11060299
Celver JP, et al. (2001) Threonine 180 is required for G-protein-coupled receptor kinase 3- and beta-arrestin 2-mediated desensitization of the mu-opioid receptor in Xenopus oocytes. J Biol Chem 276, 4894-900 11060299
This page summarizes selected information from the record referenced above and curated into PhosphoSitePlus®, a comprehensive online resource for the study of protein post-translational modifications (NAR, 2015, 43:D512-20). To learn more about the scope of PhosphoSitePlus®, click here.
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T97-p - MOR-1 (rat)
Modsite: MYVIVRYtKMKtAtN SwissProt Entrez-Gene
Orthologous residues
MOR‑1 (human): T99‑p, MOR‑1 iso5 (human): T99‑p, MOR‑1 (mouse): T97‑p, MOR‑1 (rat): T97‑p
Characterization
Methods used to characterize site in vivo mutation of modification site
Relevant cell lines - cell types - tissues:  oocyte
Cellular systems studied:  primary cells
Species studied:  frog

T101-p - MOR-1 (rat)
Modsite: VRYtKMKtAtNIyIF SwissProt Entrez-Gene
Orthologous residues
MOR‑1 (human): T103‑p, MOR‑1 iso5 (human): T103‑p, MOR‑1 (mouse): T101‑p, MOR‑1 (rat): T101‑p
Characterization
Methods used to characterize site in vivo mutation of modification site
Relevant cell lines - cell types - tissues:  oocyte
Cellular systems studied:  primary cells
Species studied:  frog

T103-p - MOR-1 (rat)
Modsite: YtKMKtAtNIyIFNL SwissProt Entrez-Gene
Orthologous residues
MOR‑1 (human): T105‑p, MOR‑1 iso5 (human): T105‑p, MOR‑1 (mouse): T103‑p, MOR‑1 (rat): T103‑p
Characterization
Methods used to characterize site in vivo mutation of modification site
Relevant cell lines - cell types - tissues:  oocyte
Cellular systems studied:  primary cells
Species studied:  frog

Y106-p - MOR-1 (rat)
Modsite: MKtAtNIyIFNLALA SwissProt Entrez-Gene
Orthologous residues
MOR‑1 (human): Y108‑p, MOR‑1 iso5 (human): Y108‑p, MOR‑1 (mouse): Y106‑p, MOR‑1 (rat): Y106‑p
Characterization
Methods used to characterize site in vivo mutation of modification site
Relevant cell lines - cell types - tissues:  oocyte
Cellular systems studied:  primary cells
Species studied:  frog

T180-p - MOR-1 (rat)
Modsite: VKALDFRtPRNAKIV SwissProt Entrez-Gene
Orthologous residues
MOR‑1 (human): T182‑p, MOR‑1 iso5 (human): T182‑p, MOR‑1 (mouse): T180‑p, MOR‑1 (rat): T180‑p
Characterization
Methods used to characterize site in vivo mutation of modification site
Relevant cell lines - cell types - tissues:  oocyte
Cellular systems studied:  primary cells
Species studied:  frog
Downstream Regulation
Effect of modification (function):  receptor desensitization, altered