Ito H, et al. (1997) Phosphorylation of alphaB-crystallin in response to various types of stress. J Biol Chem 272, 29934-41 9368070

This page summarizes selected information from the record referenced above and curated into PhosphoSitePlus®, a comprehensive online resource for the study of protein post-translational modifications (NAR, 2015, 43:D512-20). To learn more about the scope of PhosphoSitePlus®, click here.

Click on the protein name to open the protein page, and on the RSD number to open the site page.

Download

S19-p - CRYAB (human) ▲

Modsite: RPFFPFHsPsrLFDQ SwissProt Entrez-Gene Orthologous residues CRYAB (human): S19‑p, CRYAB (mouse): S19‑p, CRYAB (rat): S19‑p, CRYAB (rabbit): S19‑p, CRYAB (pig): S19‑p, CRYAB (cow): S19‑p Characterization Methods used to characterize site in vivo:  [32P] bio-synthetic labeling, mass spectrometry, phospho-antibody Disease tissue studied:  brain cancer, astrocytoma Relevant cell lines - cell types - tissues:  U373 MG (glial) Cellular systems studied:  cell lines Species studied:  human

S45-p - CRYAB (human) ▲

Modsite: FPTSTsLsPFYLrPP SwissProt Entrez-Gene Orthologous residues CRYAB (human): S45‑p, CRYAB (mouse): S45‑p, CRYAB (rat): S45‑p, CRYAB (rabbit): S45‑p, CRYAB (pig): S45‑p, CRYAB (cow): S45‑p Characterization Methods used to characterize site in vivo:  [32P] bio-synthetic labeling, mass spectrometry, phospho-antibody Disease tissue studied:  brain cancer, astrocytoma Relevant cell lines - cell types - tissues:  U373 MG (glial) Cellular systems studied:  cell lines Species studied:  human Upstream Regulation Treatments, proteins and their effect on site modification:  Treatments Referenced Treatments Manipulated Protein Referenced Protein Effect Notes arsenite increase phorbol_ester increase S45 remains heavily phosphorylated after 90 min of PMA treatment, but modestly phosphorylated after arsenite treatment. H2O2 increase anisomycin increase heat_shock increase

S59-p - CRYAB (human) ▲

Modsite: PsFLRAPsWFDTGLS SwissProt Entrez-Gene Orthologous residues CRYAB (human): S59‑p, CRYAB (mouse): S59‑p, CRYAB (rat): S59‑p, CRYAB (rabbit): S59‑p, CRYAB (pig): S59‑p, CRYAB (cow): S59‑p Characterization Methods used to characterize site in vivo:  [32P] bio-synthetic labeling, mass spectrometry, phospho-antibody Disease tissue studied:  brain cancer, astrocytoma Relevant cell lines - cell types - tissues:  U373 MG (glial) Cellular systems studied:  cell lines Species studied:  human Upstream Regulation Treatments, proteins and their effect on site modification:  Treatments Referenced Treatments Manipulated Protein Referenced Protein Effect Notes arsenite increase H2O2 increase anisomycin increase heat_shock increase