Huber AH, Weis WI (2001) The structure of the beta-catenin/E-cadherin complex and the molecular basis of diverse ligand recognition by beta-catenin. Cell 105, 391-402 11348595

This page summarizes selected information from the record referenced above and curated into PhosphoSitePlus®, a comprehensive online resource for the study of protein post-translational modifications (NAR, 2015, 43:D512-20). To learn more about the scope of PhosphoSitePlus®, click here.

Click on the protein name to open the protein page, and on the RSD number to open the site page.

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S840-p - CDH1 (mouse) ▲

Modsite: LVFDYEGsGsEAAsL SwissProt Entrez-Gene Orthologous residues CDH1 (human): S838‑p, CDH1 (mouse): S840‑p, CDH1 (rat): S842‑p Characterization Methods used to characterize site in vivo:  mass spectrometry (in vitro) Enzymes shown to modify site in vitro:  Type Enzyme KINASE CK2A1 (human) Comments:  S842 and S848 may also be phosphorylated by GSK3B in vitro. Downstream Regulation Effect of modification (function):  molecular association, regulation Modification regulates interactions with:  Interacting molecule Interacting domains Effect Consequences (function) Consequences (process) Detection assays CTNNB1 (mouse) Induces affinity chromatography

S842-p - CDH1 (mouse) ▲

Modsite: FDYEGsGsEAAsLss SwissProt Entrez-Gene Orthologous residues CDH1 (human): S840‑p, CDH1 (mouse): S842‑p, CDH1 (rat): S844‑p Characterization Methods used to characterize site in vivo:  mass spectrometry (in vitro) Enzymes shown to modify site in vitro:  Type Enzyme KINASE CK2A1 (human) Comments:  S842 and S848 may also be phosphorylated by GSK3B in vitro. Downstream Regulation Effect of modification (function):  molecular association, regulation Modification regulates interactions with:  Interacting molecule Interacting domains Effect Consequences (function) Consequences (process) Detection assays CTNNB1 (mouse) Induces affinity chromatography

S848-p - CDH1 (mouse) ▲

Modsite: GsEAAsLssLNSsEs SwissProt Entrez-Gene Orthologous residues CDH1 (human): S846‑p, CDH1 (mouse): S848‑p, CDH1 (rat): S850‑p Characterization Methods used to characterize site in vivo:  mass spectrometry (in vitro) Enzymes shown to modify site in vitro:  Type Enzyme KINASE CK2A1 (human) Comments:  S842 and S848 may also be phosphorylated by GSK3B in vitro. Downstream Regulation Effect of modification (function):  molecular association, regulation Modification regulates interactions with:  Interacting molecule Interacting domains Effect Consequences (function) Consequences (process) Detection assays CTNNB1 (mouse) Induces affinity chromatography