Franckhauser C, et al. (2010) Distinct pools of cdc25C are phosphorylated on specific TP sites and differentially localized in human mitotic cells. PLoS One 5, e11798 20668692

This page summarizes selected information from the record referenced above and curated into PhosphoSitePlus®, a comprehensive online resource for the study of protein post-translational modifications (NAR, 2015, 43:D512-20). To learn more about the scope of PhosphoSitePlus®, click here.

Click on the protein name to open the protein page, and on the RSD number to open the site page.

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T48-p - CDC25C (human) ▲
Modsite: VCPDVPRtPVGkFLG SwissProt Entrez-Gene Orthologous residues CDC25C (human): T48‑p, CDC25C iso3 (human): T48‑p, CDC25C (mouse): S48‑p, CDC25C (frog): T48‑p Characterization Methods used to characterize site in vivo:  phospho-antibody, western blotting Relevant cell lines - cell types - tissues:  HeLa (cervical) Cellular systems studied:  cell lines Species studied:  human

T67-p - CDC25C (human) ▲

Modsite: LsILsGGtPkRCLDL SwissProt Entrez-Gene Orthologous residues CDC25C (human): T67‑p, CDC25C iso3 (human): ‑, CDC25C (mouse): T66‑p, CDC25C (frog): T67‑p Characterization Methods used to characterize site in vivo:  mutation of modification site, phospho-antibody, western blotting Disease tissue studied:  bone cancer Relevant cell lines - cell types - tissues:  fibroblast, HeLa (cervical), U2OS (bone cell) Cellular systems studied:  cell lines Species studied:  human

T130-p - CDC25C (human) ▲

Modsite: PAQLLCStPNGLDRG SwissProt Entrez-Gene Orthologous residues CDC25C (human): T130‑p, CDC25C iso3 (human): T87‑p, CDC25C (mouse): T129‑p, CDC25C (frog): T138‑p Characterization Methods used to characterize site in vivo:  mutation of modification site, phospho-antibody, western blotting Disease tissue studied:  bone cancer Relevant cell lines - cell types - tissues:  fibroblast, HeLa (cervical), U2OS (bone cell) Cellular systems studied:  cell lines Species studied:  human