Curated Information
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Home > Curated Information Page > PubMed Id: 20668692
Franckhauser C, et al. (2010) Distinct pools of cdc25C are phosphorylated on specific TP sites and differentially localized in human mitotic cells. PLoS One 5, e11798 20668692
This page summarizes selected information from the record referenced above and curated into PhosphoSitePlus®, a comprehensive online resource for the study of protein post-translational modifications (NAR, 2015, 43:D512-20). To learn more about the scope of PhosphoSitePlus®, click here.
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T48-p - CDC25C (human)
Modsite: VCPDVPRtPVGkFLG SwissProt Entrez-Gene
Orthologous residues
CDC25C (human): T48‑p, CDC25C iso3 (human): T48‑p, CDC25C (mouse): S48‑p, CDC25C (frog): T48‑p
Characterization
Methods used to characterize site in vivo phospho-antibody, western blotting
Relevant cell lines - cell types - tissues:  HeLa (cervical)
Cellular systems studied:  cell lines
Species studied:  human

T67-p - CDC25C (human)
Modsite: LsILsGGtPkRCLDL SwissProt Entrez-Gene
Orthologous residues
CDC25C (human): T67‑p, CDC25C iso3 (human): , CDC25C (mouse): T66‑p, CDC25C (frog): T67‑p
Characterization
Methods used to characterize site in vivo mutation of modification site, phospho-antibody, western blotting
Disease tissue studied:  bone cancer
Relevant cell lines - cell types - tissues:  fibroblast, HeLa (cervical), U2OS (bone cell)
Cellular systems studied:  cell lines
Species studied:  human

T130-p - CDC25C (human)
Modsite: PAQLLCStPNGLDRG SwissProt Entrez-Gene
Orthologous residues
CDC25C (human): T130‑p, CDC25C iso3 (human): T87‑p, CDC25C (mouse): T129‑p, CDC25C (frog): T138‑p
Characterization
Methods used to characterize site in vivo mutation of modification site, phospho-antibody, western blotting
Disease tissue studied:  bone cancer
Relevant cell lines - cell types - tissues:  fibroblast, HeLa (cervical), U2OS (bone cell)
Cellular systems studied:  cell lines
Species studied:  human